Skip to main content

Part of the book series: Progress in Inorganic Biochemistry and Biophysics ((PIBB,volume 2))

Abstract

Magnetic resonance took on an entirely new character with the realization that it could be used for medical imaging (1) in a similar way to X-ray tomography. It was not long before it became apparent that NMR methods can have an even more fundamental impact on medicine through the observation of high resolution spectra in vivo. Often these are phosphorus-31 spectra of molecules involved in metabolism, because of the inherent simplicity of such spectra, but proton and carbon-13 high resolution spectroscopy is also feasible, and the latter offers the promise of work with isotopically enriched drugs. Medicine will never be quite the same; nor will NMR spectroscopy, for it is just now experiencing a wide publicity never dreamed of in the early days.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. P.C. Lauterbur, Nature (London), 242, 190 (1973).

    Article  Google Scholar 

  2. D.I. Hoult, J.Magn.Reson. 33, 183 (1979);

    Google Scholar 

  3. ibid. 35, 69 (1979);

    Google Scholar 

  4. ibid. 38, 369 (1980).

    Google Scholar 

  5. M.R. Bendall and R.E. Gordon, J.Magn.Reson. 53, 365 (1983).

    Google Scholar 

  6. M.R. Bendall, Chem.Phys.Letters 99, 310 (1983).

    Article  Google Scholar 

  7. R. Tycko and A. Pines, J.Magn.Reson. 60, 156 (1984).

    Google Scholar 

  8. R. Tycko and A. Pines, Chem.Phys.Letters 111, 462 (1984).

    Article  Google Scholar 

  9. W.P. Aue, S. Muller, T.A. Cross and J. Seelig, J.Magn.Reson. 56, 350 (1984).

    Google Scholar 

  10. T.A. Cross, S. Muller and W.P. Aue, J.Magn.Reson. 62, 87 (1985).

    Google Scholar 

  11. M.H. Levitt and R. Freeman, J.Magn.Reson. 33, 473 (1979).

    Google Scholar 

  12. M.H. Levitt and R.R. Ernst, J.Magn.Reson. 55, 247 (1983).

    Google Scholar 

  13. A.J. Shaka and R. Freeman, J.Magn.Reson. 55, 487 (1983).

    Google Scholar 

  14. G. Bodenhausen, R. Freeman and D.L. Turner, J.Magn.Reson. 27, 511 (1977).

    Google Scholar 

  15. A.J. Shaka and R. Freeman, J.Magn.Reson. 59, 169 (1984).

    Google Scholar 

  16. A.J. Shaka, J. Keeler, M.B. Smith and R. Freeman, J.Magn.Reson. 61, 175 (1985).

    Google Scholar 

  17. A.J. Shaka, J. Keeler, T. Frenkiel and R. Freeman, J.Magn.Reson. 52, 335 (1983).

    Google Scholar 

  18. A.J. Shaka, J. Keeler and R. Freeman, J.Magn.Reson. 53, 313 (1983).

    Google Scholar 

  19. A.J. Shaka and R. Freeman, J.Magn.Reson. (in press).

    Google Scholar 

  20. A.J. Shaka and R. Freeman, J.Magn.Reson. 62, 326 (1985).

    Google Scholar 

  21. G. Bodenhausen, R. Freeman and G.A. Morris, J.Magn.Reson. 23, 171 (1976).

    Google Scholar 

  22. G.A. Morris and R. Freeman, J.Magn.Reson. 29, 433 (1978).

    Google Scholar 

  23. A.J. Shaka and R. Freeman, J.Magn.Reson. (in press).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1986 Birkhäuser Boston, Inc.

About this chapter

Cite this chapter

Shaka, A.J., Freeman, R. (1986). Spatial Localization in NMR. In: Niccolai, N., Valensin, G. (eds) Advanced Magnetic Resonance Techniques in Systems of High Molecular Complexity. Progress in Inorganic Biochemistry and Biophysics, vol 2. Birkhäuser Boston. https://doi.org/10.1007/978-1-4615-8521-3_1

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-8521-3_1

  • Publisher Name: Birkhäuser Boston

  • Print ISBN: 978-1-4615-8523-7

  • Online ISBN: 978-1-4615-8521-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics