Abstract
One of the exciting aspects of the twenty year “interferon era” is that research in this field has been characterized by international collaboration and information exchange. A 1957 report in the Proceedings of the Royal Society by Isaacs, of England, and Lindenmann, a fellow in his laboratory from Switzerland, ushered in the interferon era (1). In retrospect, Ørskov and Andersen in 1938 probably also observed interferon production after vaccinia infection of rabbit skin (2). It is evident from a review published in 1963 that by then workers from all over the world understood the potential of interferon and were characterizing the parameters of this drug(3).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Isaacs, A., J. Lindenmann. 1957. Proc. Roy. Soc. Series B 147: 258–267.
Ørskov, V. J., E. K. Andersen. 1938. Weitere Untersuchungen über die Bildungsstätten der virusneutralisierenden Stoffe bei Vaccineinfektion von Kaninchen. Acta Pathol. Microbiol. Scand. Suppl. 37: 621–631.
Isaacs, A. 1963. Interferon. Pgs. 1–38 in K. M. Smith, M. A. Lauffer, eds. Advances in virus research volume 10. New York and London, Academic Press.
Tyrrell, D. A. J. 1959. Interferon produced by cultures of calf kidney cells. Nature 184: 452–453.
Burke, D. C. 1961. The purification of interferon. Biochem. J. 78: 553–556.
Lampson, G. P., A. A. Tytell and M. M. Nemes, etal. 1963. Purification and characterization of chick embryo interferon. Proc. Soc. Expt. Biol. Med. 112: 468–478.
Field, A. K., A. A. Tytell and G. P. Lampson, etal. 1967. Inducers of interferon and host resistance. Multistranded synthetic polynucleotide complexes. Proc. Natl. Acad. Sci. 58: 1004–1010.
Levy, H. B, G. Baer, and S. Baron, etal. 1975. A modified polyriboinosinic-polyribocytidylic acid complex that induces interferon in primates. J. Infect Dis. 132: 434–439.
Borecky, L., J. Doskocil and V. Lackovic, etal. 1975. Double-stranded RNA of Czechoslovak production in the therapy of viral skin and eye diseases. Proc. Symposium on Clinical Use of Interferon. 149–158.
Jordan, G.W., R.P. Fried and T.C. Merigan. 1974. Administration of human leucocyte interferon in herpes zoster. J. Infect Dis. 130: 56–62
Sundmachen, R., D. Neumann-Haefelin and K. Cantell. 1976. Successful treatment of dendritic keratitis with human leukocyte interferon. Albrecht v. Graefes Arch Klin Exp. Ophthal. 201: 39–45.
Jones, B. R., D. J. Coster and M. G. Falcon, etal. 1976. Topical therapy of ulcerative herpetic keratitis with human interferon. Lancet 2: 128.
Arvin, A. M. A. S. Yeager and T. C. Merigan. 1976. Effect of leukocyte interferon on urinary excretion of cytomegalovirus by infants. J. Infect Dis. 133 (Suppl.): A205–210.
Emodi, G. and M. Just. 1974. Impaired interferon responses of children with congenital CMV disease. Acta. Pediatric Scand. 63: 183–187.
Emodi, G., R. O’Reilly and A. Muller, etal. 1976. Effect of human exogenous leukocyte interferon in cytomegalovirus infections. J. Infect Dis. 133 (Suppl): A199–204.
O’Reilly, R. J. L. K. Everson and G. Emodi, etal. 1976. Effects of exogenous interferon in cytomegalovirus infections complicating bone marrow transplantation. Clin Imm. Immunopathol. 6: 51–61.
Solov’ev, V. D. 1969. The results of controlled observations on the prophylaxis of influenza with interferon. Bull Wld. Hlth. Org. 41: 683–688.
Merigan, T. C. S. E. Reed and T. S. Hall, etal. 1973. Inhibition of respiratory virus infection by locally applied interferon. Lancet 1: 563–567.
Larsson, A. M. Forsgren and S. Hard, etal. 1976. Administration of interferon to an infant with congenital rubella syndrome involving persistent viremia and cutaneous vasculitis. Acta Paediatr Scand 65: 105–110.
Greenberg, H. B., R. B. Pollard and L.I. Lutwick, etal. 1976. Effect of human leucocyte interferon on hepatitis B virus infection in patients with chronic active hepatitis. N. Engl. J. Med. 295: 517–522.
Desmyter, J. M. B. Ray and A. F. DeGroote, etal. 1976. Administration of human fibroblast interferon in chronic hepatitis B infections. Lancet 2: 645–647.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1978 Plenum Press, New York
About this chapter
Cite this chapter
Dunnick, J.K., Galasso, G.J. (1978). The Future of Interferon as an Antiviral Drug. In: Stinebring, W.R., Chapple, P.J. (eds) Human Interferon. Advances in Experimental Medicine and Biology, vol 110. Springer, New York, NY. https://doi.org/10.1007/978-1-4615-9080-4_16
Download citation
DOI: https://doi.org/10.1007/978-1-4615-9080-4_16
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4615-9082-8
Online ISBN: 978-1-4615-9080-4
eBook Packages: Springer Book Archive