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The Cl Area of Rostral Ventrolateral Medulla: Role in Tonic and Reflex Regulation of Arterial Pressure

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Central and Peripheral Mechanisms of Cardiovascular Regulation

Part of the book series: NATO ASI Series ((NSSA,volume 109))

Abstract

Although it has been known from the middle of the last century that the medulla oblongata is required for maintaining normal levels of arterial pressure (AP) (see Alexander, 1946), the identification of the specific neuronal groups within that structure which serve as sympathetic promoter neurons was not established for almost a century. Indeed, the failure of investigators to reproduce the effects of spinal cord transection on AP by local lesions within the medulla, led to the concept that the “tonic vasomotor centers” represented the action of neurons distributed along a large extent of the neuraxis rather than the activity of a collection of nerve cells within a restricted zone (Hilton, 1975).

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Authors and Affiliations

  1. Laboratory of Neurobiology, Department of Neurology, Cornell University Medical College, New York, New York, 10021, USA

    Donald J. Reis

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  1. Donald J. Reis
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Editors and Affiliations

  1. Wadsworth Center for Laboratories and Research, Albany, New York, USA

    A. Magro

  2. University of Porto, Porto, Portugal

    W. Osswald

  3. Cornell University Medical College, New York, New York, USA

    D. Reis

  4. Mayo Clinic and Mayo Foundation, Rochester, Minnesota, USA

    P. Vanhoutte

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© 1986 Plenum Press, New York

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Reis, D.J. (1986). The Cl Area of Rostral Ventrolateral Medulla: Role in Tonic and Reflex Regulation of Arterial Pressure. In: Magro, A., Osswald, W., Reis, D., Vanhoutte, P. (eds) Central and Peripheral Mechanisms of Cardiovascular Regulation. NATO ASI Series, vol 109. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9471-0_16

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  • DOI: https://doi.org/10.1007/978-1-4615-9471-0_16

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-9473-4

  • Online ISBN: 978-1-4615-9471-0

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