Abstract
Intraperitoneal application of antineoplastic drugs is neither a standard nor a widely used procedure in oncological therapy. However, some trials of this arrangement have been undertaken in clinical practice.(1–3) These drugs can induce damage to peritoneum causing a change in the diffusibility of this membrane. In order to check this side effect of cytostatics, series of experiments on isolated rabbit parietal peritoneum were performed, in which the influence of methotrexate (MTX) on the permeability of the membrane in vitro was measured.
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© 1990 Plenum Publishing Corporation
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Czyżewska, K., Ramlau, C., Knapowski, J. (1990). Methotrexate Influences Peritoneal Permeability. In: Avram, M.M., et al. Ambulatory Peritoneal Dialysis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9555-7_23
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DOI: https://doi.org/10.1007/978-1-4615-9555-7_23
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4615-9557-1
Online ISBN: 978-1-4615-9555-7
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