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Aspartame and Headache

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Dietary Phenylalanine and Brain Function

Abstract

There is evidence that aspartame consumption can provoke adverse neurological reactions, most notably headache, in a susceptible subset of the population. The available experimental and clinical data on human aspartame consumption and adverse reactions, the concept of chemical headache and its relevance to aspartame-provoked headache, the methodological issues in the assessment of adverse reactions, and the studies of aspartame-provoked neurological symptoms currently in progress are reviewed. Some future implications for the study of aspartame-provoked headache are formulated.

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Author notes

  1. Donald R. Johns

    Present address: Department of Neurology, Johns Hopkins University, Baltimore, MD, 21205, USA

Authors and Affiliations

  1. Department of Neurology, Massachusetts General Hospital, Boston, MA, 02114, USA

    Donald R. Johns

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  1. Donald R. Johns
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Editors and Affiliations

  1. Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA

    Richard J. Wurtman M.D.  & Eva Ritter-Walker  & 

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© 1988 Birkhäuser Boston

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Johns, D.R. (1988). Aspartame and Headache. In: Wurtman, R.J., Ritter-Walker, E. (eds) Dietary Phenylalanine and Brain Function. Birkhäuser Boston. https://doi.org/10.1007/978-1-4615-9821-3_37

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  • DOI: https://doi.org/10.1007/978-1-4615-9821-3_37

  • Publisher Name: Birkhäuser Boston

  • Print ISBN: 978-1-4615-9823-7

  • Online ISBN: 978-1-4615-9821-3

  • eBook Packages: Springer Book Archive

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