Abstract
Schwarz and Foltz (1957) discovered that trace amounts of selenium in the diet could protect vitamin E-deficient rats against liver necrosis. This fundamental discovery led to the recognition of “selenium-responsive” deficiency diseases in several different animal species (Nesheim and Scott, 1961; Schubert et al., 1961). The status of selenium as an essential nutrient in its own right was assured when beneficial effects due to the element were observed even in animals fed sufficient vitamin E (McCoy and Weswig, 1969; Thompson and Scott, 1969).
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References
Bunyan, J., Green, J., Edwin, E.E. and Diplock, A.T. (1961). Some antioxidant properties of L-thyroxine in biological systems. Biochim. Biophys. Acta 47:401–403.
Cash, W.D. and Gardy, M. (1965). Role of metal contaminants in the mitochondrial swelling activities of reduced and oxidized glutathione preparations. J. Biol. Chem. 240:PC3450–PC3452.
Chernick, S.S., Moe, J.G., Rodnan, G.P. and Schwarz, K. (1955). A metabolic lesion in dietary necrotic liver degeneration. J. Biol. Chem. 217:829–843.
Corwin, L.M. and Schwarz, K. (1959). An effect of vitamin E on the regulation of succinate oxidation in rat liver mitochondria. J. Biol. Chem. 234:191–197.
Diplock. A.T., Baum, H. and Lucy, J.A. (1971). The effect of vitamin E on the oxidation state of selenium in rat liver. Biochem. J. 123:721–729.
Flohe, L., Gunzler, W.A. and Schock, H.H. (1973). Glutathione peroxidase: a selenoenzyme. FEBS Lett. 32:132–134.
Froede, H.C. and Hunter, F.E., Jr. (1970). Catalytic effect of GSSG on reduction of cytochrome c by GSH—Possible model for facilitation of electron transfer and energy conservation by sulfonium ion formation. Biochem. Biophys. Res. Commun. 38: 954–961.
Green, J. (1970). Vitamin E and the biological antioxidant theory. In: The fat-soluble vitamins, eds. H.F. DeLuca and J.W. Suttie, University of Wisc. Press, Madison, Wisc, pp. 293–305.
Hurt, H.D., Cary, E.E., Allaway, W.H. and Visek, W.J. (1971). Effect of dietary selenium on the survival of rats exposed to chronic whole body irradiation. J. Nutr. 101:363–366.
Levander, O.A., Morris, V.C. and Higgs, D.J. (1973a). Acceleration of thiol-induced swelling of rat liver mitochondria by selenium. Biochemistry, in press.
Levander, O.A., Morris, V.C. and Higgs, D.J. (1973b). Selenium as a catalyst for the reduction of cytochrome c by glutathione. Biochemistry, in press.
Levander, O.A., Morris, V.C. and Varma, R.N. (1972). Effects of dietary selenium or vitamin E on the swelling of rat liver mitochondria induced by glutathione. Fed. Proc. 31:691 (Abstract).
Massey, V., Williams, C.H., Jr. and Palmer, G. (1971). The presence of S°-containing impurities in commercial samples of oxidized glutathione and their catalytic effect on the reduction of cytochrome c. Biochem. Biophys. Res. Commun. 42:730–738.
McCoy, K.E.M. and Weswig, P.H. (1969). Some selenium responses in the rat not related to vitamin E. J. Nutr. 98:383–389.
Nason, A. and Lehman, I.R. (1955). Tocopherol as an activator of cytochrome c reductase. Science 122:19–22.
Nesheim, M.C. and Scott, M.L. (1961). Nutritional effects of selenium compounds in chicks and turkeys. Fed. Proc. 20:674–678.
Neubert, D., Wojtczak, A.B. and Lehninger, A.L. (1962). Purification and enzymatic identity of mitochondrial contraction factors I and II. Proc. Nat. Acad. Sci. 48:1651–1658.
Pollard, C.J. and Bieri, J.G. (1959). Studies on the biological function of vitamin E. I. Tocopherol and reduced diphospho-pyridine nucleotide-cytochrome c reductase. Biochim. Biophys. Acta 34:420–430.
Rotruck, J.T., Pope, A.L., Ganther, H.E., Swanson, A.B., Hafeman, D.G. and Hoekstra, W.G. (1973). Selenium: biochemical role as a component of glutathione peroxidase. Science 179:588–590.
Schubert, J.R., Muth, O.H., Oldfield, J.E. and Remmert, L.F. (1961). Experimental results with selenium in white muscle disease of lambs and calves. Fed. Proc. 20:689–694.
Schwarz, K. and Foltz, C.M. (1957). Selenium as an integral part of Factor 3 against dietary necrotic liver degeneration. J. Am. Chem. Soc. 79:3292–3293.
Sprinker, L.H., Harr, J.R., Newberne, P.M., Whanger, P.D. and Weswig, P.H. (1971). Selenium deficiency lesions in rats fed vitamin E supplemented rations. Nutr. Repts. Int. 4:335–340.
Tappel, A.L. and Caldwell, K.A. (1967). Redox properties of selenium compounds related to biochemical function. In: Selenium in Biomedicine, ed. O.H. Muth. AVI Publ. Co., Westport, Conn., pp. 345–361.
Thompson, J.N. and Scott, M.L. (1969). Role of selenium in the nutrition of the chick. J. Nutr. 97:335–342.
Tsen, C.C. and Tappel, A.L. (1958). Catalytic oxidation of glutathione and other sulfhydryl compounds by selenite. J. Biol. Chem. 233:1230–1232.
Turner, D.C. and Stadtman, T.C. (1973). Purification of protein components of the clostridial glycine reductase system and characterization of protein A as a selenoprotein. Arch. Biochem. Biophys. 154:366–381.
Whanger, P.D., Pedersen, N.D. and Weswig, P.H. (1973). Selenium proteins in ovine tissues. II. Spectral properties of a 10,000 molecular weight selenium protein. Biochem. Biophys. Res. Commun. 53:1031–1035.
Wilson, D.F. and Merz, R.D. (1967). Inhibition of mitochondrial respiration by uncouplers of oxidative phosphorylation. Arch. Biochem. Biophys. 119:470–476.
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© 1974 Plenum Press, New York
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Levander, O.A., Morris, V.C., Higgs, D.J. (1974). Selenium Catalysis of Swelling of Rat Liver Mitochondria and Reduction of Cytochrome c by Sulfur Compounds. In: Friedman, M. (eds) Protein-Metal Interactions. Advances in Experimental Medicine and Biology, vol 48. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-0943-7_19
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DOI: https://doi.org/10.1007/978-1-4684-0943-7_19
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