Abstract
We have considered the nature of the bulk of the eukaryotic genome. It consists of DNA complexed with histones in nucleosomal configuration. This bulk is not transcribed into RNA. What is the nature and structure of that portion of the genome which is transcribed? Several methods for separation of transcribed from non-transcribed portions of the genome have been described. Some of these are commented upon below.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Chalkley, R., Jensen, R. (1969) Biochemistry 1: 4380–4833.
Savage, M. ,Bonner, J. (1978) In: “Methods in Cell Biology”, G. Stein and J. Stein (Eds.) Academic Press, New York, in press.
Marushige, K., Bonner, J. (1971) Proc. Nat. Acad. Sci. 68: 2941–2944.
Billing, R., Bonner, J. (1972) Biochim. Biophys. Acta 281: 453–462.
Gottesfeld, J., Garrard, W., Bagi, G., Wilson, R., Bonner, J. (1974) Proc. Nat. Acad. Sci. 71: 2193–2197.
Gottesfeld, J., Bagi, G., Berg, B., Bonner, J. (1976) Biochemistry 15: 2742–2482.
Garel, A., Axel, R. (1976) Proc. Nat. Acad. Sci. 73: 3966–3970.
Weintraub, H., Groudine, H. (1976) Science 193: 848–856.
Gottesfeld, J., Bonner, J., Radda, G., Walker, I. 0. (1974) Biochemistry 13: 2937–2945.
Hamkalo, B., Miller, O. & Bakken, A. (1973) Cold Spring Harbor Symp. on Quant. Biol. 38: 915–919.
Allfrey, V., Faulkner, R. & Mirsky, A. E. (1964) Proc. Nat. Acad. Sci. 73: 3937–3941.
Marushige, K. (1976) Proc. Nat. Acad. Sci. 73: 3937–3941.
Wallace, R. B., Sargent, T., Murphy, R., Bonner, J. (1977) Proc. Nat. Acad. Sci. 74: 3244–3248.
Bekhor, I., Kung, G.,Bonner, J. (1969) J. Mol. Biol. 32: 351–364.
Huang, R. C. C., Huang, P. C. (1969) J. Mol. Biol. 39: 365–378.
Stein, G., Maus, R., Gabby, E., Stein, J., Davis, J.,Adamadkan, P. (1975) Biochemistry 14: 1859–1866.
Paul, J., Gilmour, R., Affara, N., Birnie, G., Harrison, P., Hell, A., Humphries, S., Windass, J., Young, B. (1973) Cold Spring Harbor Symp. Quant. Biol. 38: 885–890.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1979 Springer Science+Business Media New York
About this chapter
Cite this chapter
Bonner, J. (1979). Expressed and Nonexpressed Portions of the Genome: Their Separation and their Characterization. In: Nicolini, C.A. (eds) Chromatin Structure and Function. NATO Advanced Study Institutes Series, vol 21a. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-0973-4_2
Download citation
DOI: https://doi.org/10.1007/978-1-4684-0973-4_2
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-0975-8
Online ISBN: 978-1-4684-0973-4
eBook Packages: Springer Book Archive