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Mammalian Low Density Lipoproteins

  • Chapter
Low Density Lipoproteins

Abstract

During the past few years considerable advances have been made in the study of mammalian plasma low density lipoproteins. Although human LDL is of prime interest, mainly because of its association with atherosclerosis, many studies can most satisfactorily be carried out on animals, including work on the mechanisms of LDL production and metabolism, the effects of dietary changes, and LDL involvement in atherogenesis. If knowledge were more complete it might be logical to discuss animal LDL under such functional headings, but as the emerging picture is still fragmentary it is simpler to discuss each animal separately before making some general comments on mammalian LDL.

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References

  1. L. A. Lewis, A. A. Green, and I. H. Page. 1952. Ultracentrifuge lipoprotein pattern of serum of normal, hypertensive and hypothyroid animals. Am.J. Physiol. 171:391–400.

    PubMed  CAS  Google Scholar 

  2. R. J. Havel, H. A. Eder, and J. H. Bragdon. 1955. The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J. Clin. Invest. 34:1345–1353.

    Article  PubMed  CAS  Google Scholar 

  3. L. A. Hillyard, C. Entenman, H. Feinberg, and I. L. Chaikoff. 1955. Lipid and protein composition of four fractions accounting for total serum lipoproteins. J. Biol. Chem. 214:79–90.

    PubMed  CAS  Google Scholar 

  4. M. Fried, H. G. Wilcox, G. R. Faloona, S. P. Eoff, M. S. Hoffman, and D. Zimmerman. 1968. The biosynthesis of plasma lipoproteins in higher animals. Comp. Biochem. Physiol. 25:651–661.

    Article  PubMed  CAS  Google Scholar 

  5. G. L. Mills and C. E. Taylaur. 1971. The distribution and composition of serum lipoproteins in eighteen animals. Comp. Biochem. Physiol. 40B:489–501.

    Google Scholar 

  6. K. Kirkeby. 1966. Total lipids and lipoproteins in animal species. Scand.J. Clin. Lab. Invest. 18:437–442.

    Article  PubMed  CAS  Google Scholar 

  7. C. Alexander and C. E. Day. 1973. Distribution of serum lipoproteins of selected vertebrates. Comp. Biochem. Physiol. 46B:295–312.

    Google Scholar 

  8. C. E. Day and C. Alexander. 1974. Comparative electrophoretic profiles of serum lipoproteins. In: Atherosclerosis III. Ed. by G. Schettler and A. Weizel. Springer-Verlag, New York, pp. 672–675.

    Chapter  Google Scholar 

  9. R. Delcourt. 1969. Serum lipoproteins of vertebrates. Electrophoretic and immunologic study. Acta Zool. Pathol Antverp. 48:197–220.

    PubMed  CAS  Google Scholar 

  10. H. G. Wilcox and M. Heimberg. 1970. Isolation of plasma lipoproteins by zonal ultracentrifugation in the B14 and B15 titanium rotors. J. Lipid Res. 11:7–22.

    PubMed  CAS  Google Scholar 

  11. G. Camejo. 1967. Structural studies of rat plasma lipoproteins. Biochemistry 6:3228–3241.

    Article  PubMed  CAS  Google Scholar 

  12. S. Koga, D. L. Horowitz, and A. M. Scanu. 1969. Isolation and properties of lipoproteins from normal rat serum. J. Lipid Res. 10:577–588.

    PubMed  CAS  Google Scholar 

  13. T. P. Bersot, W. V. Brown, R. I. Levy, H. G. Windmueller, D. S. Fredrickson, and V. S. LeQuire. 1970. Further characterization of the apolipoproteins of rat plasma lipoproteins. Biochemistry 9:3427–3433.

    Article  PubMed  CAS  Google Scholar 

  14. G. G. De Pury and F. D. Collins. 1972. Composition and concentration of lipoproteins in the serum of normal rats and rats deficient in essential fatty acids. Lipids 7:225–228.

    Article  PubMed  Google Scholar 

  15. N. L. Lasser, P. S. Roheim, D. Edelstein, and H. A. Eder. 1973. Serum lipoproteins of normal and cholesterol-fed rats. J. Lipid Res. 14:1–8.

    PubMed  CAS  Google Scholar 

  16. H. G. Windmueller and R. I. Levy. 1967. Total inhibition of hepatic lipoprotein production in the rat by orotic acid. J. Biol. Chem. 242:2246–2254.

    PubMed  CAS  Google Scholar 

  17. H. G. Windmueller, P. N. Herbert, and R. I. Levy. 1973. Biosynthesis of lymph and plasma lipoprotein apoproteins by isolated perfused rat liver and intestine. J. Lipid Res. 14:215–223.

    PubMed  CAS  Google Scholar 

  18. G. Schonfeld, C. Felski, and M. A. Howald. 1974. Characterization of the plasma lipoproteins of the genetically obese hyperlipoproteinemic Zucker fatty rat. J. Lipid Res. 15:457–464.

    PubMed  CAS  Google Scholar 

  19. S. Koga, L. Bolis, and A. M. Scanu. 1971. Isolation and characterization of subunit polypeptides from apoproteins of rat serum lipoprotein. Biochim. Biophys. Acta 236:416–430.

    PubMed  CAS  Google Scholar 

  20. P. Hill and D. Dvornik. 1969. Agents affecting lipid metabolism. XXXVII. Separation of rat serum lipoproteins with dextran sulfate. Can. J. Biochem. 47:1043–1047.

    Article  PubMed  CAS  Google Scholar 

  21. A. I. Kook, A. S. Eckhaus, and D. Rubinstein. 1970. The dissociation in vitro of the α-and β-lipoprotein components of human and rat low density lipoproteins. Can. J. Biochem. 48:712–724.

    Article  PubMed  CAS  Google Scholar 

  22. N. H. Fidge and I. C. Calder. 1972. Nuclear magnetic resonance studies of rat serum lipoproteins. Chem. Phys. Lipids 9:255–265.

    Article  PubMed  CAS  Google Scholar 

  23. J. A. Bowden and M. Fried. 1970. Separation and characterization of rat plasma lipoproteins by molecular sieve chromatography. Comp. Biochem. Physiol. 32:391–400.

    Article  PubMed  CAS  Google Scholar 

  24. A. J. Sinclair and F. D. Collins. 1968. Fatty livers in rats deficient in essential fatty acids. Biochim. Biophys. Acta 152:498–510.

    PubMed  CAS  Google Scholar 

  25. D. Sgoutas, R. Jones, and P. Befanis. 1973. Elaidic acid and serum lipoproteins in starved and fed rats. Nutr. Metab. 15:281–289.

    Article  PubMed  CAS  Google Scholar 

  26. J. B. Marsh. 1974. Lipoproteins in a nonrecirculating perfusate of rat liver. J. Lipid Res. 15:544–550.

    PubMed  CAS  Google Scholar 

  27. S. Eisenberg and D. Rachmilewitz. 1973. Metabolism of rat plasma very low density lipoprotein. I. Fate in circulation of the whole lipoprotein. Biochim. Biophys. Acta 326:378–390.

    PubMed  CAS  Google Scholar 

  28. S. Eisenberg and D. Rachmilewitz. 1973. Metabolism of rat plasma very low density lipoprotein. II. Fate in circulation of apoprotein subunits. Biochim. Biophys. Acta 326:391–405.

    PubMed  CAS  Google Scholar 

  29. N. H. Fidge and C. J. Foxman. 1971. In vivo transformation of rat plasma very low density lipoprotein into higher density lipoproteins. Aust. J. Exp. Biol. Med. Sci. 49:581–593.

    Article  PubMed  CAS  Google Scholar 

  30. S. Eisenberg, H. G. Windmueller, and R. I. Levy. 1973. Metabolic fate of rat and human lipoprotein apoproteins in the rat. J. Lipid Res. 14:446–458.

    PubMed  CAS  Google Scholar 

  31. C. L. Gulbrandsen, R. B. Wilson, and R. S. Lees. 1971. Conversion of human plasma very low density to low density lipoproteins in the squirrel monkey. Circulation 44 (Suppl. 2):10.

    Google Scholar 

  32. A. M. Scanu and W. L. Hughes. 1962. Further characterization of the human serum D1.063–1.21, α1 lipoprotein. J. Clin. Invest. 41:1681–1689.

    Article  PubMed  CAS  Google Scholar 

  33. R. V. Hay, L. A. Pottenger, A. L. Reingold, G. S. Getz, and R. W. Wissler. 1971. Degradation of I125-labelled serum low density lipoprotein in normal and estrogentreated male rats. Biochem. Biophys. Res. Commun. 44:1471–1477.

    Article  PubMed  CAS  Google Scholar 

  34. H. G. Windmueller, R. I. Levy, and A. E. Spaeth. 1969. Selective inhibition of hepatic but not intestinal betalipoprotein production and triglyceride transport in rats given orotic acid. In: Drugs Affecting Lipid Metabolism. Ed. by W. L. Holmes, L. A. Carlson and R. Paoletti. Plenum Press, New York, pp. 365–375.

    Google Scholar 

  35. C. Feo and E. Garçon. 1973. Study of steatosis induced in the rat by orotic acid. Biomed. Express (Paris) 19:61–64.

    CAS  Google Scholar 

  36. A. B. Novikoff, P. S. Roheim, and N. Quintana. 1966. Changes in rat liver cells induced by orotic acid feeding. Lab. Invest. 15:27–49.

    CAS  Google Scholar 

  37. L. A. Pottenger and G. S. Getz. 1971. Serum lipoprotein accumulation in the livers of orotic acid-fed rats. J. Lipid Res. 12:450–459.

    PubMed  CAS  Google Scholar 

  38. P. S. Roheim, S. Switzer, A. Girard, and H. A. Eder. 1966. Alterations of lipoprotein metabolism in orotic acid-induced fatty liver. Lab. Invest. 15:21–23.

    CAS  Google Scholar 

  39. F. F. Schlunk and B. Lombardi. 1967. On the ethionine-induced fatty liver in male and female rats. Lab. Invest. 17:299–307.

    PubMed  CAS  Google Scholar 

  40. Y. Aoyama, M. Nakanishi, and K. Ashida. 1973. Effect of methionine on liver lipid content and lipid metabolism of rats fed a protein-free diet. J. Nutr. 103:54–60.

    PubMed  CAS  Google Scholar 

  41. B. Lombardi and A. Oler. 1967. Choline deficiency fatty liver. Protein synthesis and release. Lab. Invest. 17:308–321.

    PubMed  CAS  Google Scholar 

  42. T. Fukazawa and O. S. Privett. 1972. Biosynthesis of protein relative to the accumulation of fat in the liver of EFA deficient rats. Lipids 7:387–393.

    Article  PubMed  CAS  Google Scholar 

  43. N. Takeuchi, M. Ito, and Y. Yamamura. 1973. Cholesterol metabolism in the rat sensitive to high cholesterol diet. Jpn.J. Exp. Med. 43:451–461.

    PubMed  CAS  Google Scholar 

  44. R. P. Eaton. 1972. Cobalt chloride-induced hyperlipemia in the rat: effects on intermediary metabolism. Am. J. Physiol 222:1550–1557.

    PubMed  CAS  Google Scholar 

  45. E. Baraona and C. S. Lieber. 1970. Effect of chronic ethanol feeding on serum lipoprotein metabolism in the rat. J. Clin. Invest. 49:769–778.

    Article  PubMed  CAS  Google Scholar 

  46. R. P. Eaton and D. M. Kipnis. 1969. Effect of glucose feeding on lipoprotein synthesis in the rat. Am. J. Physiol. 217:1153–1159.

    PubMed  CAS  Google Scholar 

  47. R. P. Eaton and D. M. Kipnis. 1969. Effect of high carbohydrate diets on lipid and carbohydrate metabolism in the rat. Am. J. Physiol. 217:1160–1168.

    PubMed  CAS  Google Scholar 

  48. P. Segal, P. S. Roheim, and H. Eder. 1972. Effect of clofibrate on lipoprotein metabolism in hyperlipidemic rats. J. Clin. Invest. 51:1632–1638.

    Article  PubMed  CAS  Google Scholar 

  49. J. B. Marsh and D. L. Drabkin. 1960. Experimental reconstruction of metabolic pattern of lipid nephrosis: Key role of hepatic protein synthesis in hyperlipemia. Metab. Clin. Exp. 9:946–955.

    PubMed  CAS  Google Scholar 

  50. M. Nitzan. 1973. Abnormalities of carbohydrate and lipid metabolism in experimentally induced acute uremia. Nutr. Metab. 15:187–191.

    Article  PubMed  CAS  Google Scholar 

  51. L. M. Zucker. 1965. Hereditary obesity in the rat associated with hyperlipemia. Ann N.Y. Acad. Sci. 131:447–458.

    Article  PubMed  CAS  Google Scholar 

  52. M. Friedman, S. O. Byers, and S. R. Elek. 1969. The induction of neurogenic hyper-cholesteremia. Proc. Soc. Exp. Biol. Med. 131:759–762.

    PubMed  CAS  Google Scholar 

  53. M. Friedman, S. O. Byers, and S. Elek. 1972. Neurogenic hypercholesterolemia. II. relationship to endocrine function. Am. J. Physiol. 223:473–479.

    PubMed  CAS  Google Scholar 

  54. S. O. Byers, M. Friedman, and R. Neuman. 1974. Neurogenic hypercholesterolemia: Influence upon lipoproteins. Proc. Soc. Exp. Biol. Med. 145:442–445.

    PubMed  CAS  Google Scholar 

  55. M. Friedman and S. O. Byers. 1973. The pathogenesis of neurogenic hypercholesterolemia. V. Relationship to hepatic catabolism of cholesterol. Proc. Soc. Exp. Biol. Med. 144:917–922.

    PubMed  CAS  Google Scholar 

  56. T. Tomita, Y. Yamamura, T. Nagakura, and E. Hayashi. 1973. Pharmacological study of hydroxy bis-(2-(p-chlorophenoxy)-isobutyric acid) aluminum. II. The effect of hydroxy bis-(2-(p-chlorophenoxy)-isobutyric acid) aluminum on lipid metabolism in hypercholesterolemic rats. Jpn. J. Pharmacol. 23:289–298.

    Article  PubMed  CAS  Google Scholar 

  57. L. A. Carlson, G. Walldius, and R. W. Butcher. 1972. Effect of chlorophenoxy-isobutyric acid (CPIB) on fat-mobilizing lipolysis and cyclic AMP levels in rat epididymal fat. Atherosclerosis 16:349–357.

    Article  PubMed  CAS  Google Scholar 

  58. M. N. Cayen. 1971. Effect of dietary tomatine on cholesterol metabolism in the rat. J. Lipid Res. 12:482–490.

    PubMed  CAS  Google Scholar 

  59. R. P. Eaton. 1973. Hypolipemic action of glucagon in experimental endogenous lipemia in the rat. J. Lipid Res. 14:312–318.

    PubMed  CAS  Google Scholar 

  60. C. Sardet, H. Hansma, and R. Ostwald. 1972. Characterization of guinea pig plasma lipoproteins: The appearance of new lipoproteins in response to dietary cholesterol. J. Lipid Res. 13:624–639.

    PubMed  CAS  Google Scholar 

  61. T. Bøhmer, R. J. Havel, and J. A. Long. 1972. Physiological fatty liver and hyperlipemia in the fetal guinea pig: Chemical and ultrastructural characterization. J. Lipid Res. 13:371–382.

    PubMed  Google Scholar 

  62. G. L. Mills, M. J. Chapman, and F. McTaggart. 1972. Some effects of diet on guinea pig serum lipoproteins. Biochim. Biophys. Acta 260:401–412.

    PubMed  CAS  Google Scholar 

  63. H. K. Naito and L. A. Lewis. 1973. Lipid (L), lipoprotein (LP) and protein (P) composition and concentration in six strains of guinea pig (GP). Fed. Proc. 32:934.

    Google Scholar 

  64. J. A. Glomset and K. R. Norum. 1973. The metabolic role of lecithinxholesterol acyltransferase: Perspectives from pathology. Adv. Lipid Res. 11:1–65.

    CAS  Google Scholar 

  65. R. L. Hamilton, R. J. Havel, J. P. Kane, A. E. Blaurock, and T. Sata. 1971. Cholestasis: Lamellar structure of the abnormal human serum lipoprotein. Science 172:475–478.

    Article  PubMed  CAS  Google Scholar 

  66. M. J. Chapman, G. L. Mills, and C. E. Taylaur. 1972. Lipoprotein particles from the Golgi apparatus of guinea pig liver. Biochem. J. 128:779–787.

    PubMed  CAS  Google Scholar 

  67. M. J. Chapman, G. L. Mills, and C. E. Taylaur. 1973. The effect of a lipid-rich diet on the properties of composition of lipoprotein particles from the Golgi apparatus of guinea pig liver. Biochem. J. 131:177–185.

    PubMed  CAS  Google Scholar 

  68. S. Eisenberg, D. W. Bilheimer, R. I. Levy, and F. T. Lindgren. 1973. On the metabolic conversion of human plasma very low density lipoprotein to low density lipoprotein. Biochim. Biophys. Acta 326:361–377.

    PubMed  CAS  Google Scholar 

  69. G. L. Mills and F. McTaggart. 1974. Characterization of experimental type II hyper-lipoproteinaemia in guinea pigs. In: Atherosclerosis III. Ed. by G. Schettler and A. Weizel. Springer-Verlag, New York, pp. 398–401.

    Chapter  Google Scholar 

  70. T. Langer, W. Strober, and R. I. Levy. 1972. The metabolism of low density lipoprotein in familial type II hyperlipoproteinemia. J. Clin. Invest. 51:1528–1536.

    Article  PubMed  CAS  Google Scholar 

  71. P. J. Scott and P. J. Hurley. 1969. Effect of clofibrate on low-density lipoprotein turnover in essential hypercholesterolaemia. J. Aiheroscler. Res. 9:25–34.

    Article  CAS  Google Scholar 

  72. P. J. Hurley and P. J. Scott. 1970. Plasma turnover of S f 0–9 low density lipoprotein in normal men and women. Atherosclerosis 11:51–76.

    Article  PubMed  CAS  Google Scholar 

  73. L. A. Simons, D. Reichl, N. B. Myant, and M. Mancini. 1975. The metabolism of the apoprotein of plasma low density lipoprotein in familial hyperbetalipoproteinaemia in the homozygous form. Atherosclerosis 21:283–298.

    Article  PubMed  CAS  Google Scholar 

  74. G. Camejo, V. Bosch, C. Arreaza, and H. C. Mendez. 1973. Early changes in plasma lipoprotein structure and biosynthesis in cholesterol-fed rabbits. J. Lipid Res. 14:61–68.

    PubMed  CAS  Google Scholar 

  75. V. G. Shore, B. Shore, and R. G. Hart. 1974. Changes in apolipoproteins and properties of rabbit very low density lipoproteins on induction of cholesteremia. Biochemistry 13:1579–1585.

    Article  PubMed  CAS  Google Scholar 

  76. D. B. Zilversmit, L. B. Hughes, and M. Remington. 1972. Hypolipidemic effect of pregnancy in the rabbit. J. Lipid Res. 13:750–756.

    PubMed  CAS  Google Scholar 

  77. H. Kang-Jey and C. B. Taylor. 1971. Mode of cholesterol accumulation in various tissues of rabbits with moderate hypercholesteremia. Proc. Soc. Exp. Biol. Med. 136:249–252.

    Google Scholar 

  78. M. P. Westerman, R. Glen Wiggans, III, and R. Mao. 1970. Anemia and hypercholesterolemia in cholesterol-fed rabbits. J. Lab. Clin. Med. 75:893–902.

    PubMed  CAS  Google Scholar 

  79. J. T. Prior, D. M. Kurtz, and D. D. Ziegler. 1961. The hypercholesterolemic rabbit. Arch. Pathol. 71:672–684.

    PubMed  CAS  Google Scholar 

  80. J. M. Dietschy and J. D. Wilson. 1970. Regulation of cholesterol metabolism. N. Engl. J. Med. 282:1128–1138., 1179-1183, 1241-1249.

    Article  PubMed  CAS  Google Scholar 

  81. V. N. Schumaker. 1956. Cholesterolemic rabbit lipoproteins: Serum lipoproteins of the cholesterolemic rabbit. Am. J. Physiol. 184:35–42.

    PubMed  CAS  Google Scholar 

  82. J. W. Gofman, F. Lindgren, H. Elliot, W. Mantz, J. Hewitt, B. Strisower, and V. Herring. 1950. The role of lipids and lipoproteins in atherosclerosis. Science 111:166–186.

    Article  PubMed  CAS  Google Scholar 

  83. D. G. Garlick and F. C. Courtice. 1962. The composition of the lipoproteins in the plasma of rabbits with hypercholesterolemia or Triton WR-1339 induced hyper-lipemia Q. J. Exp. Physiol. 47:211–220.

    CAS  Google Scholar 

  84. D. G. Garlick, F. C. Courtice, and M. Munoz-Marcos. 1965. Plasma lipoproteins in hyperlipaemic states in man and in the rabbit. Austr. Ann. Med. 14:102–110.

    CAS  Google Scholar 

  85. H. C. Klauda and D. B. Zilversmit. 1974. Influx of cholesterol into plasma in rabbits with fasting hyperbetalipoproteinemia. J. Lipid Res. 15:593–601.

    PubMed  CAS  Google Scholar 

  86. E. F. Annison, J. L. Linzell, S. Frazakerely, and B. W. Nichols. 1967. The oxidation and utilization of palmitate, stearate, oleate and acetate by the mammary gland of the fed goat in relation to their overall metabolism, and the role of plasma phospholipids and neutral lipids in milk fat synthesis. Biochem. J. 102:637–647.

    PubMed  CAS  Google Scholar 

  87. J. M. Barry, W. Bartley, J. L. Linzell, and D. S. Robinson. 1963. Uptake from the blood of triglycéride fatty acids of chylomicra and lipoproteins by the mammary gland of the goat. Biochem. J. 89:6–11.

    PubMed  CAS  Google Scholar 

  88. C. Bishop, T. Davies, R. F. Glascock, and V. A. Welch. 1969. Studies on the origin of milk fat. Biochem. J. 113:629–633.

    PubMed  CAS  Google Scholar 

  89. R. F. Glascock, V. A. Welch, C. Bishop, T. Davies, E. W. Wright, and R. C. Noble. 1966. An investigation of serum lipoproteins and of their contribution to milk fat in the dairy cow. Biochem. J. 98:149–156.

    PubMed  CAS  Google Scholar 

  90. L. Evans, S. Patton, and R. D. McCarthy. 1961. Fatty acid composition of the lipid fractions from bovine serum lipoproteins. J. Dairy Sci. 44:475–482.

    Article  CAS  Google Scholar 

  91. R. M. Wendlandt and C. L. Davis. 1973. Characterization of bovine serum lipoproteins. J. Dairy Sä. 56:337–339.

    Article  CAS  Google Scholar 

  92. B. C. Raphael, P. S. Dimick, and D. L. Puppione. 1973. Lipid characterization of bovine serum lipoproteins throughout gestation and lactation. J. Dairy Sci. 56:1025–1032.

    Article  PubMed  CAS  Google Scholar 

  93. B. C. Raphael, P. S. Dimick, and D. L. Puppione. 1973. Electrophoretic characterization of bovine serum lipoproteins throughout gestation and lactation. J. Dairy Sci. 56:1411–1414.

    Article  PubMed  CAS  Google Scholar 

  94. D. L. Puppione, G. M. Forte, A. V. Nichols, and E. H. Strisower. 1970. Partial characterization of serum lipoproteins in the density interval 1.04–1.06 g/ml. Biochim. Biophys. Acta 202:392–395.

    PubMed  CAS  Google Scholar 

  95. D. L. Puppione, B. Raphael, R. D. McCarthy, and P. S. Dimick. 1972. Variations in the electrophoretic distribution of low density lipoproteins of Holstein cows. J. Dairy Sci. 55:265–267.

    Article  CAS  Google Scholar 

  96. K. D. Wiggers, N. L. Jacobson, and R. Getty. 1971. Experimental atherosclerosis in the young bovine. Atherosclerosis 14:379–389.

    Article  PubMed  CAS  Google Scholar 

  97. K. D. Wiggers, N. L. Jacobson, R. Getty, and M. Richard. 1973. Mode of cholesterol ingestion and atherosclerosis in the young bovine. Atherosclerosis 17:281–295.

    Article  PubMed  CAS  Google Scholar 

  98. K. Perk and K. Lobl. 1960. Chemical and paper electrophoretic analysis of normal sheep serum proteins and lipoproteins. Br. Vet. J. 116:167–174.

    Google Scholar 

  99. G. J. Nelson. 1973. The lipid composition of plasma lipoprotein density classes of sheep Ovis aries. Comp. Biochem. Physiol. 46B:81–191.

    Google Scholar 

  100. H. L. Ratcliffe and H. Luginbühl. 1971. The domestic pig: A model for experimental atherosclerosis. Atherosclerosis 13:133–136.

    Article  PubMed  CAS  Google Scholar 

  101. J. E. French and M. A. Jennings. 1965. The tunica intima of arteries of swine. In: Comparative Atherosclerosis. Ed. by J. C. Roberts and R. Straus. Hoeber Medical Divn., Harper and Row, New York, pp. 25–36 and Atlas pp. 12-15.

    Google Scholar 

  102. R. Getty. 1965. The gross and microscopic occurrence and distribution of spontaneous atherosclerosis in the arteries of swine. In: Comparative Atherosclerosis. Ed. by J. C. Roberts and R. Straus. Hoeber Medical Divn., Harper and Row, New York, pp. 11–20 and Atlas pp. 6-11.

    Google Scholar 

  103. M. Janado, W. G. Martin, and W. H. Cook. 1966. Separation and properties of pig serum lipoproteins. Can. J. Biochem. 44:1201–1209.

    Article  PubMed  CAS  Google Scholar 

  104. N. Fidge. 1973. The isolation and properties of pig plasma lipoproteins and partial characterisation of their apoproteins. Biochim. Biophys. Acta 295:258–273.

    PubMed  CAS  Google Scholar 

  105. R. L. Jackson, H. N. Baker, O. D. Taunton, L. C. Smith, C. W. Garner, and A. M. Gotto. 1973. A comparison of the major apolipoproteins from pig and human high density lipoproteins. J. Biol. Chem. 248:2639–2644.

    PubMed  CAS  Google Scholar 

  106. R. W. Mahley and K. H. Weisgraber. 1974. An electrophoretic method for the quantitative isolation of human and swine plasma lipoproteins. Biochemistry 13:1964–1969.

    Article  PubMed  CAS  Google Scholar 

  107. G. D. Calvert and P. J. Scott. 1975. Properties of two pig low-density lipoproteins prepared by zonal ultracentrifugation. Atherosclerosis 22:583–599.

    Article  PubMed  CAS  Google Scholar 

  108. R. S. Levy, A. C. Lynch, E. D. McGee, and J. W. Mehl. 1967. Amino acid composition of the proteins from chylomicrons and human serum lipoproteins. J. Lipid Res. 8:463–472.

    PubMed  CAS  Google Scholar 

  109. A. D. Sniderman, T. E. Carew, and D. Steinberg. 1972. Metabolism of low density lipoprotein apoprotein in the pig. Circulation 46(Suppl 11):249.

    Google Scholar 

  110. A. D. Sniderman, T. E. Carew, J. G. Chandler, S. Hayes, and D. Steinberg. 1973. The role of the liver in metabolism of low density lipoproteins (LDL). J. Clin. Invest. 52:79a.

    Google Scholar 

  111. A. D. Sniderman, T. E. Carew, J. G. Chandler, and D. Steinberg. 1974. Paradoxical increase in rate of catabolism of low density lipoproteins after hepatectomy. Science 183:526–528.

    Article  PubMed  CAS  Google Scholar 

  112. D. Steinberg. 1974. Lipoprotein catabolism. In: Atherosclerosis III. Ed. by G. Schettler and A. Weizel. Springer-Verlag, New York, pp. 658–671.

    Chapter  Google Scholar 

  113. G. D. Calvert, P. J. Scott, and D. N. Sharpe. 1975. The plasma and tissue turnover and distribution of two radio-iodine-labelled pig plasma low-density lipoproteins. Atherosclerosis 22:601–628.

    Article  PubMed  CAS  Google Scholar 

  114. J. J. Albers, C.-H. Chen, and F. Aladjem. 1972. Human serum lipoproteins. Evidence for three classes of lipoproteins in S f 0–2. Biochemistry 11:57–63.

    Article  PubMed  CAS  Google Scholar 

  115. G. D. Calvert and P. J. Scott. 1974. Serum lipoproteins in pigs on high-cholesterol-high-triglyceride diets. Atherosclerosis 19:485–492.

    Article  PubMed  CAS  Google Scholar 

  116. R. P. Link, W. M. Pedersoli, and A. H. Safani. 1972. Effect of exercise on development of atherosclerosis in swine. Atherosclerosis 15:107–122.

    Article  PubMed  CAS  Google Scholar 

  117. E. G. Hill, W. O. Lundberg, and J. L. Titus. 1971. Experimental atherosclerosis in swine. I. A comparison of menhaden-oil supplements in tallow and coconut-oil diets. Mayo Clin. Proc. 46:613–620.

    PubMed  CAS  Google Scholar 

  118. E. G. Hill, W. O. Lundberg, and J. L. Titus. 1971. Experimental atherosclerosis in swine. II. Effects of methionine and menhaden oil on an atherogenic diet containing tallow and cholesterol. Mayo Clin. Proc. 46:621–625.

    PubMed  CAS  Google Scholar 

  119. J. H. Bragdon, J. H. Zeller, and J. W. Stevenson. 1957. Swine and experimental atherosclerosis. Proc. Soc. Exp. Biol. Med. 95:282–284.

    PubMed  CAS  Google Scholar 

  120. J. Rapacz, R. H. Grummer, J. Hasler, and R. M. Schackelford. 1970. Allotype polymorphism of low density β-lipoproteins in pig serum. Nature 225:941–942.

    Article  PubMed  CAS  Google Scholar 

  121. J. Rapacz, J. Hasler-Rapacz, R. H. Grummer, and R. M. Shackelford. 1972. A low density B-lipoprotein allotype system (Lpp) in swine. Proc. XIHth Eur. Conf. Anim. Blood Groups Biochem. Polymorph. Vienna, Abstract 2.2.3.3.

    Google Scholar 

  122. J. Rapacz, I. Wiatroszak, and J. Hasler-Rapacz. 1972. Isoprecipitins in immune antipig blood sera. Proc. XIHth Eur. Conf. Anim. Blood Groups Biochem. Polymorph. Vienna, Abstract 2.2.3.2.

    Google Scholar 

  123. M. D. Morris, D. B. Zilversmit, and H. F. Hintz. 1972. Hyperlipoproteinemia in fasting ponies. J. Lipid Res. 13:383–389.

    PubMed  CAS  Google Scholar 

  124. J. C. Roberts, R. C. Boice, R. L. Brownell, and D. H. Brown. 1965. Spontaneous atherosclerosis in Pacific toothed and baleen whales. In: Comparative Atherosclerosis. Ed. by J. C. Roberts and R. Straus. Hoeber Medical Divn., Harper and Row, New York, pp. 151–155 and Atlas pp. 60-67.

    Google Scholar 

  125. D. L. Puppione, T. Forte, and A. V. Nichols. 1971. Serum lipoproteins of killer whales. Comp. Biochem. Physiol. 39B:673–681.

    Google Scholar 

  126. S. Hashimoto, S. Dayton, and J. C. Roberts. 1967. Aliphatic wax alcohols and other lipids in atheromata and arterial tissues of cetaceans. Comp. Biochem. Physiol. 20:975–986.

    Article  CAS  Google Scholar 

  127. D. L. Puppione and A. V. Nichols. 1970. Characterization of the chemical and physical properties of the serum lipoproteins of certain marine mammals. Physiol. Chem. Phys. 2:49–58.

    CAS  Google Scholar 

  128. R. W. Mahley, K. H. Weisgraber, and D. L. Fry. 1973. Canine lipoproteins and atherosclerosis. Fed. Proc. 32:294.

    Google Scholar 

  129. D. Adlersberg, E. T. Bossack, I. H. Sher, and H. Sobotka. 1955. Electrophoresis and monomolecular layer studies with serum lipoproteins. Clin. Chem. 1:18–33.

    PubMed  CAS  Google Scholar 

  130. R. H. Furman, L. N. Norcia, C. W. Robinson, and I. E. Gonzalez. 1957. Influence of testosterone, methyltestosterone and dl-ethionine on canine liver lipids, serum lipids and lipoproteins. Am. J. Physiol. 191:561–572.

    PubMed  CAS  Google Scholar 

  131. A. Solyom, R. H. Bradford, and R. H. Furman. 1971. Apolipoprotein and lipid distribution in canine serum lipoproteins. Biochim. Biophys. Acta 229:471–483.

    PubMed  CAS  Google Scholar 

  132. A. Solyom, R. H. Bradford, and R. H. Furman. 1971. Effect of methyltestosterone on the apolipoprotein and lipid composition of canine serum lipoproteins. Biochim. Biophys. Acta 236:563–570.

    PubMed  CAS  Google Scholar 

  133. D. G. Cornwell and F. A. Kruger. 1961. Molecular complexes in the isolation and characterization of plasma lipoproteins. J. Lipid Res. 2:110–134.

    PubMed  CAS  Google Scholar 

  134. A. Solyom. 1972. Effect of androgens on serum lipids and lipoproteins. Lipids 7:100–105.

    Article  PubMed  CAS  Google Scholar 

  135. A. W. Lindall, F. Grande, and A. Schultz. 1971. The effect of dietary fats on the serum lipoproteins of normal dogs. Proc. Soc. Exp. Biol Med. 136:1032–1037.

    PubMed  CAS  Google Scholar 

  136. A. W. Lindall, F. Grande, and A. Schultz. 1972. Effect of dietary fats on the serum lipoproteins in thyroidectomized dogs. J. Nutr. 102:515–522.

    PubMed  CAS  Google Scholar 

  137. D. P. Barr, E. M. Russ, H. A. Eder, F. E. Kendall, and L. L. Abell. 1955. Protein-lipid relationships in experimental canine atherosclerosis. Circ. Res. 3:199–202.

    PubMed  CAS  Google Scholar 

  138. L. J. Milch, A. A. Renzi, N. Weiner, L. G. Robinson, and S. S. Wilson. 1958. Hyperlipoproteinemia and cholesterol deposition at the arteries of I131-treated dogs. Proc. Soc. Exp. Biol. Med. 97:56–59.

    PubMed  CAS  Google Scholar 

  139. J. Marmorston, S. Rosenfeld, and J. Mehl. 1959. Experimental atherosclerosis. In: Hormones and Atherosclerosis. Ed. by G. Pincus. Academic Press, New York, p. 213.

    Google Scholar 

  140. P. J. Manning, L. A. Corwin, Jr., and C. C. Middleton. 1973. Familial hyperlipoproteinemia and thyroid dysfunction of beagles. Exp. Mol. Pathol. 19:378–388.

    Article  PubMed  CAS  Google Scholar 

  141. W. L. Holmes. 1973. Factors affecting lipoprotein metabolism in the dog. Abstract A35, Conference on Serum Lipoproteins, Graz, Austria, Oct. 21-23.

    Google Scholar 

  142. S. H. Quarfordt, H. Oelschlaeger, W. R. Krigbaum, L. Jakoi, and R. Davis. 1973. Effect of biliary obstruction on canine plasma and biliary lipids. Lipids 8:522–530.

    Article  PubMed  CAS  Google Scholar 

  143. S. H. Quarfordt, H. Oelschlaeger, and W. R. Krigbaum. 1972. Liquid crystalline lipid in the plasma of humans with biliary obstruction. J. Clin. Invest. 51:1979–1988.

    Article  PubMed  CAS  Google Scholar 

  144. P. J. Manning and T. B. Clarkson. 1973. Diet induced atherosclerosis in the cat. Arch. Pathol 89:271–278.

    Google Scholar 

  145. A. M. Scanu, C. Edelstein, L. Vitello, R. Jones, and R. Wissler. 1973. The serum high density lipoproteins of Macacus rhesus. I. Isolation, composition and properties. J. Biol Chem. 248:7648–7652.

    PubMed  CAS  Google Scholar 

  146. C. Edelstein, C. T. Lim, and A. M. Scanu. 1973. The serum high density lipoproteins of Macacus rhesus. II. Isolation, purification, and characterization of their two major polypeptides. J. Biol Chem. 248:7653–7660.

    PubMed  CAS  Google Scholar 

  147. D. A. Eggen. 1974. Cholesterol metabolism in rhesus monkey, squirrel monkey and baboon. J. Lipid Res. 15:139–145.

    PubMed  CAS  Google Scholar 

  148. H. B. Lofland, R. W. St. Clair, and D. G. Freene. 1974. Certain aspects of lipid metabolism in the young squirrel monkey (Saimirisciureus). In: Atherosclerosis III. Ed. by G. Schettler and A. Weizel, Springer-Verlag, New York, pp. 376–380.

    Google Scholar 

  149. J. A. Lee and M. D. Morris. 1974. Characterization of the serum low-density lipoproteins of normal and two rhesus monkeys with spontaneous hyperbetalipoproteinemia. Biochem. Med. 10:245–257.

    Article  PubMed  CAS  Google Scholar 

  150. G. V. Mann, S. B. Andrus, A. McNally, and F. J. Stare. 1956. Xanthomatosis and atherosclerosis produced by diet in an adult rhesus monkey. J. Lab. Clin. Med. 48:533–550.

    PubMed  CAS  Google Scholar 

  151. C. B. Taylor, G. E. Cox, P. Manalo-Estrella, and J. Southworth. 1962. Atherosclerosis in rhesus monkeys. II. Arterial lesions associated with hypercholesteremia induced by dietary fat and cholesterol. Arch. Pathol. 74:16–34.

    PubMed  CAS  Google Scholar 

  152. C. B. Taylor, D. E. Patton, and G. E. Cox. 1963. Atherosclerosis in rhesus monkeys. V. Marked diet-induced hypercholesteremia with xanthomatosis and severe atherosclerosis. Arch. Pathol 76:239–249.

    PubMed  CAS  Google Scholar 

  153. R. F. Scott, E. S. Morrison, J. Jarmolych, S. C. Nam, M. Kroms, and F. Coulston. 1967. Experimental atherosclerosis in rhesus monkeys. I. Gross and light microscopy features and lipid values in serum and aorta. Exp. Mol. Pathol. 7:11–33.

    Article  PubMed  CAS  Google Scholar 

  154. R. F. Scott, R. Jones, A. S. Daoud, O. Zumbo, F. Coulston, and W. A. Thomas. 1967. Experimental atherosclerosis in rhesus monkeys. II. Cellular elements of prolifera-tive lesions and possible role of cytoplasmic degeneration in pathogenesis as studied by electron microscopy. Exp. Mol. Pathol. 7:34–57.

    Article  PubMed  CAS  Google Scholar 

  155. R. W. Wissler. 1968. Recent progress in studies of experimental primate atherosclerosis. Prog. Biochem. Pharmacol 4:378–392.

    CAS  Google Scholar 

  156. R. K. Younger, W. H. Scott, Jr., W. H. Butts, and S. E. Stephenson, Jr. 1969. Rapid production of experimental hypercholesterolemia and atherosclerosis in the rhesus monkey. Comparison of five dietary regimens. J. Surg. Res. 9:263–271.

    Article  PubMed  CAS  Google Scholar 

  157. M. L. Armstrong and E. D. Warner. 1971. Morphology and distribution of diet-induced atherosclerosis in rhesus monkeys. Arch. Pathol. 92:395–401.

    PubMed  CAS  Google Scholar 

  158. P. J. Manning and T. B. Clarkson. 1972. Development, distribution and lipid content of diet-induced atherosclerotic lesions of rhesus monkeys. Exp. Mol. Pathol. 17:35–54.

    Article  Google Scholar 

  159. M. L. Armstrong and M. B. Megan. 1974. Responses of two macaque species to atherogenic diet and its withdrawal. In: Atherosclerosis III. Ed. by G. Scheider and A. Weizel. Springer-Verlag, New York, pp. 336–338.

    Chapter  Google Scholar 

  160. D. M. Kramsch and W. Hollander. 1968. Occlusive atherosclerotic disease of the coronary arteries in monkey (Macaca irus) induced by diet. Exp. Mol. Pathol. 9:1–22.

    Article  PubMed  CAS  Google Scholar 

  161. C. B. Campbell, D. J. Cowley, and R. H. Dowling. 1972. Dietary factors affecting biliary lipid secretion in the rhesus monkey. A mechanism for the hypocholesterolaemic action of polyunsaturated fat? Eur. J. Clin. Invest. 2:332–341.

    Article  PubMed  CAS  Google Scholar 

  162. R. Fraser, L. Dubien, F. Musil, E. Fosslien, and R. W. Wissler. 1972. Transport of cholesterol in thoracic duct lymph and serum of rhesus monkeys fed cholesterol with various food fats. Atherosclerosis 16:203–216.

    Article  PubMed  CAS  Google Scholar 

  163. N. L. Lasser and J. F. Allebaugh. 1974. Density distribution of plasma lipoproteins in rhesus monkeys: Differential effect of an atherogenic diet in males and females. In: Atherosclerosis III. Ed. by G. Schettler and A. Weizel. Springer-Verlag, New York, p. 874.

    Google Scholar 

  164. M. D. Morris and C. D. Fitch. 1968. Spontaneous hyperbetalipoproteinemia in the rhesus monkey. Biochem. Med. 2:209–215.

    Article  CAS  Google Scholar 

  165. M. D. Morris and W. E. Greer. 1970. Familial hyperbetalipoproteinemia (Type II hyperlipoproteinemia) in the rhesus monkey. In: Atherosclerosis. Ed. by R. J. Jones. Springer-Verlag, New York, p. 192.

    Google Scholar 

  166. J. C. Pinon and P. Laudat. 1969. Apoprotéine-β du plasma: composition en acides aminés dans l’hypercholestérolémie du type II familiale. Biochim. Biophys. Acta 187:144–146.

    PubMed  CAS  Google Scholar 

  167. C. A. Nelson, J. A. Lee, M. Brewster, and M. D. Morris. 1974. Flotation equilibrium of serum low density lipoproteins. Anal. Biochem. 59:69–74.

    Article  PubMed  CAS  Google Scholar 

  168. M. D. Morris and J. A. Lee. 1974. Serum lipids and low density lipoproteins: Spontaneous hypercholesterolemia vs. cholesterol feeding in rhesus monkeys. In: Atherosclerosis III. Ed. by G. Schettler and A. Weizel. Springer-Verlag, New York, pp. 374–376.

    Google Scholar 

  169. M. L. Armstrong, W. E. Connor, and E. D. Warner. 1967. Xanthomatosis in rhesus monkeys fed a hypercholesterolemic diet. Arch. Pathol. 84:227–237.

    PubMed  CAS  Google Scholar 

  170. C. O. Thoen, A. G. Karlson, and R. E. Ellefson. 1973. Comparison of serum lipid and lipoprotein profiles of tuberculin-positive and tuberculin-negative monkeys (Macaca sp). Am. Rev. Resp. Dis. 108:686–687.

    PubMed  CAS  Google Scholar 

  171. J. P. Strong, J. Rosal, R. H. Deupree, and H. C. McGill, Jr. 1966. Diet and serum cholesterol levels in baboons. Exp. Mol. Pathol. 5:82–91.

    Article  PubMed  CAS  Google Scholar 

  172. J. P. Strong and H. C. McGill. 1967. Diet and experimental atherosclerosis in baboons. Am. J. Pathol. 50:669–687.

    PubMed  CAS  Google Scholar 

  173. V. Blaton and H. Peeters. 1969. Lipid and fatty acid modifications in plasma lipoproteins of baboons under atherogenic diet. Acta Zool. Pathol. Antverp. 48:233–242.

    PubMed  CAS  Google Scholar 

  174. V. Blaton, A. N. Howard, G. A. Gresham, D. Vandamme, and H. Peeters. 1970. Lipid changes in the plasma lipoproteins of baboons given an atherogenic diet. Part 1. Changes in the lipids of total plasma and of α-and β-lipoproteins. Atherosclerosis 11:497–507.

    Article  PubMed  CAS  Google Scholar 

  175. G. V. Mann, S. B. Andrus, A. McNally, and F. J. Stare. 1953. Experimental atherosclerosis in cebus monkeys. J. Exp. Med. 98:195–218.

    Article  PubMed  CAS  Google Scholar 

  176. R. W. Wissler, L. E. Frazier, R. H. Hughes, and R. A. Rasmussen. 1962. Atherogenesis in the cebus monkey. I. A comparison of three food fats under controlled dietary conditions. Arch. Pathol. 74:312–322.

    PubMed  CAS  Google Scholar 

  177. G. V. Mann. 1963. Diet and cholesterolemia in chimpanzees. Fed. Proc. 22:268.

    Google Scholar 

  178. A. N. Howard, V. Blaton, D. Vandamme, N. Van Landschoot, and H. Peeters. 1972. Lipid changes in the plasma lipoproteins of baboons given an atherogenic diet. 3. A comparison between lipid changes in the plasma of the baboon and chimpanzee given atherogenic diets and those in human plasma lipoproteins of type II hyperlipoproteinaemia. Atherosclerosis 16:257–272.

    Article  PubMed  CAS  Google Scholar 

  179. A. N. Howard, G. A. Gresham, D. E. Bowyer, and F. T. Lindgren. 1968. Aortic and coronary atherosclerosis in baboons. Prog. Biochem. Pharmacol. 4:438–444.

    Google Scholar 

  180. D. Kritchevsky, L. M. Davidson, I. L. Shapiro, H. K. Kim, M. Kitagawa, S. Malhotra, P. P. Nair, T. B. Clarkson, I. Bersohn, and P. A. Winter. 1974. Lipid metabolism and experimental atherosclerosis in baboons: Influence of cholesterol-free, semi-synthetic diets. Am. J. Clin. Nutr. 27:29–50.

    PubMed  CAS  Google Scholar 

  181. D. Kritchevsky. 1974. Effect of dietary carbohydrate on aortic sudanophilia in baboons. In: Atherosclerosis III. Ed. by G. Schettler and A. Weizel. Springer-Verlag, New York, pp. 386–388.

    Google Scholar 

  182. V. Blaton, D. Vandamme, B. Declercq, M. Vastesaeger, J. Mortelmans, and H. Peeters. 1974. Dietary induced hyperbetalipoproteinemia in chimpanzees: Comparison to the human hyperlipoproteinemia. Exp. Mol. Pathol. 20:132–146.

    Article  PubMed  CAS  Google Scholar 

  183. M. Vastesaeger, V. Blaton, B. Declercq, J. Vercruysse, D. Vandamme, H. Peeters, and J. Mortelmans. 1974. Comparative treatment of hyperlipoproteinaemias in chimpanzees. Acta Zool. Pathol. Antverp. 58:79–96.

    PubMed  CAS  Google Scholar 

  184. C. C. Middleton, T. B. Clarkson, H. B. Lofland, and R. W. Prichard. 1964. Atherosclerosis in the squirrel monkey. Arch. Pathol. 78:16–23.

    PubMed  CAS  Google Scholar 

  185. T. B. Clarkson, H. B. Lofland, B. C. Bullock, and H. O. Goodman. 1971. Genetic control of plasma cholesterol. Studies on squirrel monkeys. Arch. Paihol. 92:37–45.

    CAS  Google Scholar 

  186. H. B. Lofland, D. G. Green, and R. W. St. Clair. 1973. Lipoprotein metabolism in non-human primates as influenced by diet. Abstract A31, Conference on Serum Lipoproteins, Graz, Austria, Oct. 21-23.

    Google Scholar 

  187. H. B. Lofland, R. W. St. Clair, T. B. Clarkson, B. C. Bullock, and N.D.M. Lehner. 1968. Atherosclerosis in Cebus monkeys. II. Arterial metabolism. Exp. Mol. Pathol. 9:57–70.

    Article  PubMed  Google Scholar 

  188. S. R. Srinivasan, E. R. Dalferes, Jr., H. Ruiz, P. S. Pargaonkar, B. Radhakrishnamurthy, and G. S. Berenson. 1972. Rapid serum lipoprotein changes in spider monkeys on short-term feeding of high cholesterol-high saturated fat diet. Proc. Soc. Exp. Biol. Med. 141:154–160.

    PubMed  CAS  Google Scholar 

  189. K. W. Walton and S. J. Darke. 1963. Immunological characteristics of human low-density lipoproteins and their relation to lipoproteins of other species. Protides Biol. Fluids. Proc. Colloq. 10:146–148.

    CAS  Google Scholar 

  190. K. Bauer. 1974. Cross-reactions between human and animal plasma proteins. VI. An assay method for ape and monkey plasma proteins using antihuman antisera. Humangenetik 21:273–278.

    Article  PubMed  CAS  Google Scholar 

  191. G. J. Bautovich, L. A. Simons, P. F. Williams, and J. R. Turtle. 1975. Radioimmunoassay of human plasma apolipoproteins. Part 1 (Assay of apolipoprotein-B). Atherosclerosis 21:217–234.

    Article  PubMed  CAS  Google Scholar 

  192. R. W. Mahley and K. H. Weisgraber. 1974. Canine lipoproteins and atherosclerosis. I. Isolation and characterization of plasma lipoproteins from control dogs. Circ. Res. 35:713–721.

    PubMed  CAS  Google Scholar 

  193. R. W. Mahley, K. H. Weisgraber, and T. Innerarity. 1974. Canine lipoproteins and atherosclerosis. II. Characterization of the plasma lipoproteins associated with atherogenic and nonatherogenic hyperlipidemia. Circ. Res. 35:722–733.

    PubMed  CAS  Google Scholar 

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  1. Department of Clinical Biochemistry, Flinders Medical Centre, Bedford Park, 5042, South Australia, Australia

    G. D. Calvert

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    Charles E. Day

  2. Department of Biochemistry, University of Louisville School of Medicine, Louisville, Kentucky, USA

    Robert S. Levy

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Calvert, G.D. (1976). Mammalian Low Density Lipoproteins. In: Day, C.E., Levy, R.S. (eds) Low Density Lipoproteins. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2250-4_11

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