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Radioiodinated Estrogens and Antiestrogens as Potential Imaging Agents

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Steroid Hormone Action and Cancer

Part of the book series: Current Topics in Molecular Endocrinology ((CTME,volume 4))

Abstract

In an earlier chapter, Dr. William McGuire reviewed studies demonstrating that estradiol is selectively taken up by certain mammary tumors in addition to other target tissues such as uterus and pituitary. It has been our goal for the past ten years to synthesize an agent labelled with a gamma-emitting nuclide that would mimic estradiol in this selective uptake process. Theoretically, such an agent would be a useful diagnostic agent in Nuclear Medicine for the imaging of estrogen responsive tissues and tumors.

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References

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Author information

Authors and Affiliations

  1. Laboratory of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, Michigan, USA

    R. E. Counsell, A. Buswink, N. Korn, M. Johnson, V. Ranade & T. Yu

Authors
  1. R. E. Counsell
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  2. A. Buswink
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  3. N. Korn
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  4. M. Johnson
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  5. V. Ranade
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  6. T. Yu
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Editor information

Editors and Affiliations

  1. University of Michigan Medical School, Ann Arbor, Michigan, USA

    K. M. J. Menon

  2. Parke Davis Research Laboratories, Ann Arbor, Michigan, USA

    Jerry R. Reel

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© 1976 Plenum Press, New York

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Counsell, R.E., Buswink, A., Korn, N., Johnson, M., Ranade, V., Yu, T. (1976). Radioiodinated Estrogens and Antiestrogens as Potential Imaging Agents. In: Menon, K.M.J., Reel, J.R. (eds) Steroid Hormone Action and Cancer. Current Topics in Molecular Endocrinology, vol 4. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2601-4_9

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  • DOI: https://doi.org/10.1007/978-1-4684-2601-4_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-2603-8

  • Online ISBN: 978-1-4684-2601-4

  • eBook Packages: Springer Book Archive

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