Abstract
The rat liver glutathione S-transferases are a family of enzymes which catalyze the conjugation of the reduced sulfhydryl group of glutathione with various electrophiles. In addition, the transferases bind with high affinity various exogenous hydrophobic compounds as well as potentially toxic endogenous compounds such as bilirubin and heme (1–3). The enzymes are comprised of binary combinations of at least six major subunits, Yα, Ya, Ybl, Yb2, Yc and Yn, which can be separated by onedimensional SDS-polyacrylamide gel electrophoresis (4–6).
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© 1986 Plenum Press, New York
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Pickett, C.B., Telakowski-Hopkins, C.A., Ding, G.JF., Ding, V.DH. (1986). Expression and Sequence Analysis of Rat Liver Glutathione S-Transferase Genes. In: Kocsis, J.J., Jollow, D.J., Witmer, C.M., Nelson, J.O., Snyder, R. (eds) Biological Reactive Intermediates III. Advances in Experimental Medicine and Biology, vol 197. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5134-4_15
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DOI: https://doi.org/10.1007/978-1-4684-5134-4_15
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