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Transport of Immune Complexes from the Subcapsular Sinus into the Lymph Node Follicles of the Rat

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Histophysiology of the Immune System

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 237))

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Abstract

Immune complexes localize in lymphoid follicles of different lym-phoid organs. It has been shown that immune complex trapping in lymphoid follicles depends on the presence of complement factor C3 (1,2). The complexes are retained in follicular centers for a long time, although they may be replaced gradually by new complexes from the circulation (3).Trapping and retaining of immune complexes by follicular dendritic cells (FDC) may play an important role in the generation of immunological memory, feedback inhibition of the immune response or in both of these processes (4).

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Authors and Affiliations

  1. Department of Cell Biology, Medical Faculty, Free University, NL-1007, MC Amsterdam, The Netherlands

    E. W. A. Kamperdijk, E. A. Döpp & C. D. Dijkstra

Authors
  1. E. W. A. Kamperdijk
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  2. E. A. Döpp
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  3. C. D. Dijkstra
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Editor information

Editors and Affiliations

  1. Anatomical Institute, Oslo, Norway

    Sigbjørn Fossum  & Bent Rolstad  & 

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© 1988 Plenum Press, New York

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Kamperdijk, E.W.A., Döpp, E.A., Dijkstra, C.D. (1988). Transport of Immune Complexes from the Subcapsular Sinus into the Lymph Node Follicles of the Rat. In: Fossum, S., Rolstad, B. (eds) Histophysiology of the Immune System. Advances in Experimental Medicine and Biology, vol 237. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5535-9_28

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  • DOI: https://doi.org/10.1007/978-1-4684-5535-9_28

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5537-3

  • Online ISBN: 978-1-4684-5535-9

  • eBook Packages: Springer Book Archive

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