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5-Fluorouracil and Folinic Acid: Summary of Clinical Experience

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The Expanding Role of Folates and Fluoropyrimidines in Cancer Chemotherapy

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 244))

Abstract

In summarizing the clinical experience with 5-fluorouracil (FU) and folinic acid (FA) I shall approach it in the context of some critical questions which may be used to determine where we currently stand and where information still needs to be sought with respect to the clinical activity of this modulation. These questions are listed in Table 1.

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Authors and Affiliations

  1. Department of Clinical Pharmacology and Therapeutics, Roswell Park Memorial Institute, Buffalo, New York, 14263, USA

    Patrick J. Creaven

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  1. Roswell Park Memorial Institute, Buffalo, New York, USA

    Youcef Rustum  & John J. McGuire  & 

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© 1988 Plenum Press, New York

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Creaven, P.J. (1988). 5-Fluorouracil and Folinic Acid: Summary of Clinical Experience. In: Rustum, Y., McGuire, J.J. (eds) The Expanding Role of Folates and Fluoropyrimidines in Cancer Chemotherapy. Advances in Experimental Medicine and Biology, vol 244. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-5607-3_33

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  • DOI: https://doi.org/10.1007/978-1-4684-5607-3_33

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