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A CCD Spectrophotometer to Quantitate the Concentration of Chromophores in Living Tissue Utilising the Absorption Peak of Water at 975 nm

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Oxygen Transport to Tissue XI

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 248))

Abstract

Optical spectroscopy has long been used to study the oxygenation of living tissue in-vivo. It is possible to detect concentration changes of naturally occurring chromophores whose absorption spectra are affected by the presence of oxygen, such as haemoglobin and the cytochrome enzymes.

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References

  • Brunori, M., Antonini, E., and Wilson, M.T., 1981, Cytochrome C Oxidase: An overview of recent work, in: “Metal ions in Biological Systems”, H. Siegel, ed., Dekker, N.Y.

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  • Wray, S., Cope, M., Delpy, D.T., Wyatt, J.S., and Reynolds, E.O.R., 1988, Characterization of the near infrared absorption spectra of cytochrome aa3 and haemoglobin for the non-invasive monitoring of cerebral oxygenation, Biochim. Biophvs, Acta. 933:184–192.

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Author information

Authors and Affiliations

  1. Department of Medical Physics and Bioengineering, University College London, 11-20 Capper Street, London, WC1E 6JA, UK

    M. Cope & D. T. Delpy

  2. Department of Physiology, University College London, 11-20 Capper Street, London, WC1E 6JA, UK

    S. Wray

  3. Department of Paediatrics, University College London, 11-20 Capper Street, London, WC1E 6JA, UK

    J. S. Wyatt & E. O. R. Reynolds

Authors
  1. M. Cope
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  2. D. T. Delpy
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  3. S. Wray
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  4. J. S. Wyatt
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  5. E. O. R. Reynolds
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Editor information

Editors and Affiliations

  1. University of Ottawa, Ottawa, Ontario, Canada

    Karel Rakusan  & George P. Biro  & 

  2. Northwestern University, Evanston, Illinois, USA

    Thomas K. Goldstick

  3. University of Nijmegen, Nijmegen, The Netherlands

    Zdenek Turek

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© 1989 Plenum Press, New York

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Cope, M., Delpy, D.T., Wray, S., Wyatt, J.S., Reynolds, E.O.R. (1989). A CCD Spectrophotometer to Quantitate the Concentration of Chromophores in Living Tissue Utilising the Absorption Peak of Water at 975 nm. In: Rakusan, K., Biro, G.P., Goldstick, T.K., Turek, Z. (eds) Oxygen Transport to Tissue XI. Advances in Experimental Medicine and Biology, vol 248. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5643-1_4

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  • DOI: https://doi.org/10.1007/978-1-4684-5643-1_4

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5645-5

  • Online ISBN: 978-1-4684-5643-1

  • eBook Packages: Springer Book Archive

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