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Local Hyperthermia for Deep Tumors

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Consensus on Hyperthermia for the 1990s

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 267))

Abstract

Hyperthermia for superficial tumors has been considered standard treatment since 1984, based on multiple reports showing synergistic therapeutic advantage in combination with radiotherapy compared to irradiation alone (Table 1). Results of external hyperthermia treatments for deep tumors combined with irradiation or chemotherapy have shown significant improvement over controls (24).

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References

  1. Arcangeli, G; Benassi, M; Cividalli, A; et al: Radiotherapyand hyperthermia. Analysis of clinical results and identification of prognostic variables. Cancer 60: 950–956, 1987.

    Article  PubMed  CAS  Google Scholar 

  2. Scott, RS; Johnson, RJR; Story, KV; et al: Local hyperthermia in combination with definitive radiotherapy: Increased tumor clearance, reduced recurrence rate in extended Follow–up. Int. J. Radiat. Oncol. Biol. Phys. 10: 21. 19–2123, 1984.

    Google Scholar 

  3. U, R; Noell, T; Woodward, KT; et al: Microwave–induced local hyperthermia in combination with radiotherapy of human malignant tumors. Cancer 45: 636–646, 1980.

    Google Scholar 

  4. Kim, JH; Hahn, EW; Antich, PE: Radiofrequency hyperthermia for clinical cancer therapy. Natl. Cancer Inst. Mongr. 61: 339–342, 1982.

    CAS  Google Scholar 

  5. Kim, J H; Hahn, E W; Ahmed, SA; et al: Combination hyperthermia and radiation therapy for malignant melanoma. Cancer 50: 478–482, 1982.

    Article  PubMed  CAS  Google Scholar 

  6. Overgaard, J The current and potential role of hyperthermia in radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 16: 535–549, 1989

    Article  PubMed  CAS  Google Scholar 

  7. Corry, Pm; Barlogie, B; Tilchen, EJ; et al: Ultrasound induced hyperthermia for the treatment of human superficial tumors. Int. J. Radiat. Oncol. Biol. Phys. 8: 1225–1229, 1982

    Google Scholar 

  8. Hiraoka, M; Jo, S; Dodo, Y; et al: Clinical results of radiofrequency hyperthermia combined with radiation in the treatment of radioresistant cancer. Cancer 54: 2898–2904, 1984

    Article  PubMed  CAS  Google Scholar 

  9. Li, RY; Wang, HP; Lin, SY; et al: Clinical evaluation of combined radiotherapy and thermotherapy on carcinoma of the breast. Clin. Oncol. 12: 73–76, 1985

    Google Scholar 

  10. Shidnia, H; Hornback, NB; Shupe, RE; et al: Correlation between hyperthermia and large dose per fraction in treatment of Malignant Melanoma (Abstr.) Int. Clin. Hyperthermia Soc. Meeting, Lund Sweden, 1987.

    Google Scholar 

  11. Perez, Ca; Kuske, RR; Emani, Betal: Irradiation alone or combined with hyperthermia in the treatment of recurrent carcinoma of the breast in the chest wall. A nonranomized comparison. Int. J. Hyperthermia 2: 179–187, 1986

    Google Scholar 

  12. Van Der Zee, J; Van Rhoon, GC; Wike-Hooley, JL; et al: Clinically derived dose effect relationship for hyperthermia with low dose radiotherapy. Br. J. Radiol. 58: 243–250, 1985

    Article  PubMed  Google Scholar 

  13. Steeves, RA; Severson, SB; Paliwal, BR; et al: Matched - pair analysis of response to local hyperthermia and megavoltage electron therany for superficial tumors. Endocurietheraoy/Hyperthermia Oncol. 2: 163–170, 1986

    Google Scholar 

  14. Dunlop, PRC; Hand, JW; Dickinson, RJ; et al An assessment of local hyperthermia in clinical practice. Int. J. Hyperthermia 2: 39–50, 1986.

    PubMed  CAS  Google Scholar 

  15. Goldobenko, GV; Durnov, LA; Knysh, VI; et al. Experience in the use of thermoradiotherapy of malignant tumors. Med. Radiol. 32: 36–37, 1987.

    CAS  Google Scholar 

  16. Muratkhodzhaev, NK; Svetitsky, PV; Kochegarov, AA; et al: Hyperthermia in therapy of cancer patients. Med. Radiol. 32: 30–36, 1987.

    CAS  Google Scholar 

  17. Lindholm, CE; Kjellen, E; Nilsson, P; et al: Microwave–induced hyperthermia and radiotherapy in human superficial tumors. Clinical results with a comparative study of combined treatment versus radiotherapy alone. Int. J. hyperthermia. 3: 393–411, 1987.

    Article  PubMed  CAS  Google Scholar 

  18. Valdagni, R; Amichetti, M; Pani, G: Radical radiation alone versus radical radiation plus microwave hyperthermia for N3 neck nodes: A prospective randomized clinical trial. Int. J. Radiat. Oncol. Biol. Phys. 15: 13–24, 1988

    PubMed  CAS  Google Scholar 

  19. Emami, B; Perez, CA; Konefal, J; et al: Thermoradiotherapy of malignant melanoma. Int. J. Hyperthermia 4: 373–381, 1988

    Article  PubMed  CAS  Google Scholar 

  20. Marmor, JB; Hahn, GM; Combined radiation and hyperthermia in superficial human tumors. Cancer 46: 1986–1991, 1980.

    Article  PubMed  CAS  Google Scholar 

  21. Combined treatment with radiation and hyperthermia in metastatic malignant melanoma. Radiother. Oncol. 6: 105–113, 1986

    Google Scholar 

  22. Gonzalez Gonzalez, D; Van Dijk, JDP; Blank, LECM; et al. Chest wall recurrence of breast cancer Results of combined treatment with radiation and hyperthermia. Radiother. Oncol. 12: 95–103: 1988

    Article  PubMed  CAS  Google Scholar 

  23. Silberman,AW; Rand, RW; Krag, DN; et al: Effect of localized magnetic–induction hyperthermia on the brain. Cancer 57: 1401–1404, 1986

    Article  Google Scholar 

  24. Hornback, NB; Shupe, RE; Shidnia, H; et al: Advanced stage III B cancer of the cervix treatment by hyperthermia and radiation. Gyn. Oncol. 23; 160–167, 1986.

    Article  CAS  Google Scholar 

  25. Sapozink, MD; Gibbs, FA; Thomson, JW; et al: A comparison of deep regional hyperthermia from an annular array and a concentric coil in the same patients. Int. J. Radiat. Oncol. Biol. Phys. 11: 179–190, 1985

    Article  PubMed  CAS  Google Scholar 

  26. Pilepich, MV; Myerson, RS; Emami, BN; et al: Regional hyperthermia assessment of tolerance to treatment. Int. J. Radiat. Oncol. Biol. Phys. 14: 347–352, 1988

    Article  PubMed  CAS  Google Scholar 

  27. Bicher, HI; Wolfstein, RS: Local hyperthermia for deep tumors–Experience with three techniques. J. Microwave Power 21: 21st International Microwave Power Symposium Summaries, 103–104, 1986

    Google Scholar 

  28. Hiraoka, M; Jo, S; Akuta, K; et al: Regional hyperthermia for cancer. Am. J. Surgery 143: 586–590, 1982

    Article  Google Scholar 

  29. Bicher, HI; Moore, DW; Wolfstein RS: Air - cooled 300 MHz applicators used in a parallel opposed phased system (POPAS). (Abstr.) Int. J. Radiat. Oncol. Biol. Phys. 11: Si: 217, 1985

    Google Scholar 

  30. Bicher, HI; Wolfstein, RS: Local superficial and deep hyperthermia - Factors affecting tumor response and patient survival (Abstr). Presented at 37th Annual Meeting of the Radiation Research Society, Seattle, Wash. 3/18–23/ 1989

    Google Scholar 

  31. Storm, K; Baker, HW; Scanlon, EF; et al: Magnetic induction hyperthermia. Results of a 5 year multi–institutional national cooperative trial in advanced cancer patients. Cancer 55: 2677–2687, 1985

    Article  PubMed  CAS  Google Scholar 

  32. Petrovich, Z; Langholz, B; Gibbs, FA; et al: Regional hyperthermia for advanced tumors: A clinical study of 353 patients. Int. J. Radiat. Oncol. Biol. Phys. 16: 601–607, 1989

    Article  PubMed  CAS  Google Scholar 

  33. Hiraoka, M; Jo, S; Akuta, K; et al: Radiofrequency capacitive hyperthermia for deep–seated tumors. II. Effects of thermoradiotherapy. Cancer 60: 128–135, 1987

    Article  PubMed  CAS  Google Scholar 

  34. Lokich, JJ; Ahlgren, JD; Gullo, JJ; et al: Aprospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: A Mid–Atlantic Oncology Program study. J. Clin. Oncol. 7: 425–432, 1989

    PubMed  CAS  Google Scholar 

  35. Storm, KF; Scanlon, EF; Baker, HW; et al: Tumor stabilization after hyperthermia: An important criterion of response to thermal therapy. J. Surg.Oncol. 34: 143–149, 1987

    Article  PubMed  CAS  Google Scholar 

  36. Bicher, HI.; Hetzel, FW; Sandhu, TS; et al: Effects of hyperthermia on normal and tumor microenvironment. Radiology 137: 523–530, 1980

    PubMed  CAS  Google Scholar 

  37. Bicher, HI; Hetzel, FW; Sandhu TS: Physiology and morphology of tumor microcirculation in hyperthermia. In Storm, FK (ed): Hyperthermia in Cancer Therapy. Year Book Medical Publishers, 1985,pp 207–222.

    Google Scholar 

  38. Egana, S; Tsukiyana,I; Akine, Y; et al: Hyperthermia therapy of deep seated tumors: Comparison of the heating efficiencies of an annular array applicator and a capacitively coupled radiofrequency system. Int. J. Radiat. Oncol. Biol. Phys. 14, 521–528, 1988.

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Valley Cancer Institute, Panorama City, Los Angeles, CA, USA

    Haim I. Bicher & Ralph S. Wolfstein

Authors
  1. Haim I. Bicher
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  2. Ralph S. Wolfstein
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Editor information

Editors and Affiliations

  1. Valley Cancer Institute, Los Angeles, California, USA

    Haim I. Bicher M.D.

  2. Emory Clinic, Atlanta, Georgia, USA

    John R. McLaren

  3. II University of Rome, Rome, Italy

    Giuseppe M. Pigliucci

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© 1990 Plenum Press, New York

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Bicher, H.I., Wolfstein, R.S. (1990). Local Hyperthermia for Deep Tumors. In: Bicher, H.I., McLaren, J.R., Pigliucci, G.M. (eds) Consensus on Hyperthermia for the 1990s. Advances in Experimental Medicine and Biology, vol 267. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5766-7_42

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  • DOI: https://doi.org/10.1007/978-1-4684-5766-7_42

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5768-1

  • Online ISBN: 978-1-4684-5766-7

  • eBook Packages: Springer Book Archive

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