Abstract
Previous papers of this laboratory have shown that rat kallikreins (urinary, pancreatic and salivary) besides their kininogenic activity exhibit the peculiarity of eliciting contraction of rat uterus apparently independent of a substrate in the uterus. As both properties appear at the same zone of the electrophoretic tracing it is suggested that a single substance is responsible for the effects on uterus and plasma. However, certain reagents inhibit only the kininogenic activity leaving the oxytocicunaffected (Beraldo et al, 1966; Araujo et al, 1970 and Siqueira et al, 1970).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Reference
Araujo, R. L., W. Dias da Silva and W. T. Beraldo. Kininogenic and oxytocic properties of rat pancreatic juice. In Bradykinin and Related Kinins: Cardiovascular, Biochemical, and Neural Actions. Plenum Press,1970.
Beraldo, W. T., R. L. Araujo and M. Mares-Guia. Oxytocic esterase in rat urine. Am: J. Physiol. 211, 975, 1966.
Gaddum, J. H. The technique of superfusion. Brit. J. Pharmacol. 8, 321, 1953.
Mares-Guia, M. and C.R. Diniz. Studies on the mechanism of rat urinary kallikrein catalysis, and its relation to catalysis by trypsin. Arch. Biochem. and Biophys. 121, 750, 1967.
Prado, E. S., J. L. Prado and C. M. W. Brandi. Further purification and some properties of horse urinary kallikrein. Arch. int. Pharmacodyn. CXXXVII, 358, 1962.
Bhoola, K. D. and P. F. Heap. Properties of kallikrein-containing granules isolated from the submaxillary gland of the guinea-pig. J. Physiol. 210, 421, 1970.
Lowry, O. H., N. J. Rosebrough, A. L. Farr and R. J. Randall. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 265, 1951.
Jacoby, F. and C.R. Leeson. The post-natal development of the rat submaxillary gland. J.Anat. 93, 201, 1959.
Sreebny, L. M., J. Meyer, E. Bachem and J. P. Weinmann. Post- natal changes in proteolytic activity and in the morphology of the submaxillary gland in male and female albino rats. Growth, 19, 57, 1955.
Riekkienem, P. J., T. O. Ekfors, T. Hollmen and V. K. HopsuHavu. Purification and physical characteristics of a trypsin-like protease from the rat submandibular gland. Enzymology, 32, 97, 1967.
Rothschild, H. and Junqueira, L. C. V. The possible correlation between cathepsin activity and protein synthesis. Arch. Biochem. and Biophys. 34, 453, 1951.
Siqueira, G., W. Dias da Silva and W. T. Beraldo. A kinin-like forming enzyme in saliva presenting a potent oxytocic activity. In Bradykinin and Related Kinins: Cardiovascular, Biochemical and Neural Actions. Plenum Press, 1970.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1972 Plenum Press, New York
About this chapter
Cite this chapter
Beraldo, W.T., Siqueira, G., Rodrigues, J.A.A., Machado, C.R.S. (1972). Changes in Kallikrein Activity of Rat Submandibular Gland during Post-Natal Development. In: Back, N., Sicuteri, F. (eds) Vasopeptides. Advances in Experimental Medicine and Biology, vol 21. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7439-8_27
Download citation
DOI: https://doi.org/10.1007/978-1-4684-7439-8_27
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-7441-1
Online ISBN: 978-1-4684-7439-8
eBook Packages: Springer Book Archive