Abstract
The pathogenesis of bacterial meningitis comprises a sequence of several distinct events; acquisition of the causative bacterium from another individual, colonization, invasion of mucosal epithelium resulting in bacteremia, haematogenous dissemination, invasion of the blood-brain barrier and, finally, the occurrence of inflammatory changes within the subarachnoid space consequent upon bacterial multiplication within the central nervous system (Figure 1).
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© 1991 Plenum Press, New York
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Moxon, E.R., Weiser, J.N. (1991). Studies on the Genetic Basis of Haemophilus Influenzae Pathogenicity. In: Ron, E.Z., Rottem, S. (eds) Microbial Surface Components and Toxins in Relation to Pathogenesis. Federation of European Microbiological Societies Symposium Series, vol 51. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8995-8_19
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