Abstract
Electrophysiological investigations of the cellular actions of dopamine had focused in the past on its direct action on cell bodies of the postsynaptic neuron, assuming dopamine to be a neuromediating transmitter. Recent evidence suggests, however, that while dopamine undoubtedly has actions on the cell bodies of postsynaptic neurons, it may also have an important presynaptic neuromodulatory action on non-dopaminergic inputs to the ventral striatum (see Yim and Mogenson, 1986). There is also evidence that peptides such as cholecystokinin which coexists with dopamine in a subpopulation of the mesolimbic dopamine neurons may in turn modulate the neuromodulatory action of dopamine.
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© 1991 Plenum Press, New York
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Yim, C.CY., Sheehy, L., Mogenson, G. (1991). Neuromodulatory Actions of Dopamine and Cholecystokinin in the Ventral Striatum. In: Napier, T.C., Kalivas, P.W., Hanin, I. (eds) The Basal Forebrain. Advances in Experimental Medicine and Biology, vol 295. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0145-6_8
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DOI: https://doi.org/10.1007/978-1-4757-0145-6_8
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