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Biosynthesis of Collagen during the Life Cycle of Human Diploid Cell Lines

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Cell Impairment in Aging and Development

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 53))

Abstract

The senescence of human diploid fibroblasts and their limited lifespan in vitro, shown by Hayflick and Moorhead (1), suggested a possible relationship between these events and ageing in vivo. In this paper we report our observations concerning the problems of collagen synthesis of human diploid cell strains during their long term in vitro cultivation.

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© 1975 Springer Science+Business Media New York

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Hurych, J., Macek, M., Smetana, K., Beniač, F., Řezáčová, D. (1975). Biosynthesis of Collagen during the Life Cycle of Human Diploid Cell Lines. In: Cristofalo, V.J., Holečková, E. (eds) Cell Impairment in Aging and Development. Advances in Experimental Medicine and Biology, vol 53. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0731-1_29

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  • DOI: https://doi.org/10.1007/978-1-4757-0731-1_29

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-0733-5

  • Online ISBN: 978-1-4757-0731-1

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