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Emergence of Ptsd-Type Reactivity in Sprague-Dawley Rats Following Prenatal Gamma Irradiation

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Contemporary Issues in Modeling Psychopathology

Part of the book series: Neurobiological Foundation of Aberrant Behaviors ((NFAB,volume 1))

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Abstract

Posttraumatic Stress Disorder (PTSD) is believed to be precipitated by stressors which are markedly distressing to almost anyone (DSM-III), so that the major experimental paradigms relevant for modeling PTSD have emphasized the necessity of traumatic history for development of conditioned fear. By contrast, the necessity of an innate (unconditioned) fear as a prerequisite for PTSD has not received a proper hearing. The potential of the traumatic precipitant is somewhat reduced by the fact that not everyone will have gone to pieces in conditions of severe stress whereas others are expected to develop PTSD following relatively ‘mild’ psychological trauma (Foy et al., 1987). Lord Taylor (1978) noticed that during WWII, only a fraction of the civil population (about 10%) were afflicted in the bombed cities in England. Somewhat apologetically he called them “the psychopathic tenth.” This variation in response to stress is in keeping with an old conviction that the syndrome “depends not only upon the kind of injury, but upon the kind of brain” (Symonds, 1937, p. 464).

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Authors
  1. Matti Mintz
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  2. Michael Myslobodsky
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Editors and Affiliations

  1. Psychobiology Research Unit, Department of Psychology, Tel Aviv University, 69978, Tel-Aviv, Israel

    Michael S. Myslobodsky

  2. Howard University, USA

    Michael S. Myslobodsky

  3. Department of Psychology, Tel Aviv University, 69978, Tel-Aviv, Israel

    Ina Weiner

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Mintz, M., Myslobodsky, M. (2000). Emergence of Ptsd-Type Reactivity in Sprague-Dawley Rats Following Prenatal Gamma Irradiation. In: Myslobodsky, M.S., Weiner, I. (eds) Contemporary Issues in Modeling Psychopathology. Neurobiological Foundation of Aberrant Behaviors, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-4860-4_11

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