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Are Autopsies still Useful in the Intensive Care Unit?

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Intensive Care Medicine
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Abstract

As early as 1912, autopsy was noted by Cabot to be a medical procedure to obtain a diagnosis in complex cases, to provide quality assessment of clinical practice, and to improve understanding of medical limitations [1, 2]. Anderson et al. [3] defined quality assessment as the quantitative evaluation of results or outcomes ranged within predefined acceptable limits Although in the United States, the institutional requirements of the Accreditation Council for Graduate Medical Education stated that a sufficient number of autopsies should be performed to maintain quality of patient care and for educational purposes, the autopsy rate has fallen over recent decades, from 50% in the 1940s to 10% in the 1980s [4]. This decline has been attributed to a number of factors, including:

  • the fear of diagnostic errors being detected at autopsy;

  • heary work for the pathologists;

  • the high non-reimbursable cost involved in the procedure;

  • difficulties in obtain consent from the family; and

  • the greater sensitivity and specificity of modern diagnostic techniques [5, 6].

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References

  1. Cabot RC (1912) Diagnostic pitfalls identified during a study of 3000 autopsies. JAMA 59: 2295–2298

    Article  Google Scholar 

  2. Goldman L (1984) Diagnostic advances vs the valve of the autopsy. Arch Pathol Lab Med 108: 501–505

    PubMed  CAS  Google Scholar 

  3. Anderson RE (1984) The autopsy as an instrument of quality assessment: Classification of postmortem and premortem diagnostic discrepancies. Arch Pathol Lab Med 108: 490–493

    PubMed  CAS  Google Scholar 

  4. Accreditation Council for Graduate Medical Education (1996) Revised essentials of accredited residencies in graduate medical education. Part I, Institutional Requirements. ACGME Bulletin. ACGME, Chicago

    Google Scholar 

  5. Landefeld CS, Chren MM, Myers A, Geller R, Robbins S, Goldman L (1988) Diagnostic yield of the autopsy in a university hospital and a community hospital. N Engl J Med 318: 1249–1254

    Article  PubMed  CAS  Google Scholar 

  6. McPhee SJ, Bottles K (1985) Autopsy: Moribund art or viral science? Am J Med 78: 107–113

    Article  PubMed  CAS  Google Scholar 

  7. Hasson J, Gross H (1974) The autopsy and quality assessment of medical care. Am J Med 56: 137–140

    Article  PubMed  CAS  Google Scholar 

  8. Battle R, Pathack D, Humble CC, et al (1987) Factors influencing discrepancies between premortem and postmortem diagnosis. JAMA 258: 339–344

    Article  PubMed  CAS  Google Scholar 

  9. Cameron HM, McCoogan E (1981) A prospective study of 1152 hospital autopsies. II. Analysis of inaccuracies in clinical diagnoses and their significance. J Pathol 133: 285–300

    Article  Google Scholar 

  10. Gibinski K, Hartleb M, Koturbasz D (1985) Comparison between pre-and post-mortem diagnoses in a consecutive series of patients. Scand J Gastroenterol 20: 370–372

    Article  PubMed  CAS  Google Scholar 

  11. Stephanovic G, Tucakovic G, Dotlic R, Kanjuh V (1986) Correlation of clinical diagnoses with athopsy findings: A retrospective study of 2145 consecutive autopsies. Hum Pathol 17: 1225–1230

    Article  Google Scholar 

  12. Landefeld CS, Goldman L (1989) The autopsy in clinical medicine. Mayo Clin Proc 64: 1185–1189

    Article  PubMed  CAS  Google Scholar 

  13. Goldman L, Sayson R, Robbins S, et al (1983) The value of autopsy in three medical eras. N Engl J Med 308: 1000–1005

    Article  PubMed  CAS  Google Scholar 

  14. Fernandez-Segoviano P, Lazaro A, Esteban A, et al (1988) Autopsy as quality assurance in the intensive care unit. Crit Care Med 16: 683–685

    Article  PubMed  CAS  Google Scholar 

  15. Blosser SA, Zimmerman HE, Stauffer JL (1998) Do autopsies of critically ill patients reveal important findings that were clinically undetected. Crit Care Med 26: 1332–1336

    Article  PubMed  CAS  Google Scholar 

  16. Mort TC, Yeston NS (1999) The relationship of pre-mortem diagnoses and post-mortem findings in a surgical intensive care unit. Crit Care Med 27: 299–303

    Article  PubMed  CAS  Google Scholar 

  17. Roosen J, Frans E, Wilmer A, Knockaert DC, Bobbaers H (2000) Comparison of postmortem clinical diagnoses in critically ill patients and subsequent autopsy findings. Mayo Clin Proc 75: 562–657

    Article  PubMed  CAS  Google Scholar 

  18. Tai D, El-Bilbeisi H, Tewari S, et al (2001) A study of consecutive autopsies in a medical ICU. A comparison of clinical cause of death and autopsy diagnosis. Chest 119: 530–536

    Article  PubMed  CAS  Google Scholar 

  19. Podbregar M, Voga G, Krivec B, Skale R, Poreznik R, Gabrescek L (2001) Should we confirm our clinical diagnostic certainty by autopsies. Intensive Care Med 27: 1756–1761

    Article  Google Scholar 

  20. Goldstein B, Metlay L, Cox C, Rubenstein JS (1996) Association of pre mortem diagnosis and autopsy findings in pediatric intensive care unit versus emergency department versus ward patients. Crit Care Med 24: 683–686

    Article  PubMed  CAS  Google Scholar 

  21. Cameron HM, McCoogan E, Watson H (1980) Necropsy: a yardstick for clinical diagnoses. Br Med J 281: 985–988

    Article  PubMed  CAS  Google Scholar 

  22. Ferretti GR, Bosson JL, Buffaz PD, et al (1997) Acute pulmonary embolism: Role of helical CT in 164 patients with intermediate probability at ventilation-perfusion scintigraphy and normal results at duplex US of the legs. Radiology 205: 453–458

    PubMed  CAS  Google Scholar 

  23. Gouello JP, Asfar P, Brenet O, et al (2000) Nosocomial endocarditis in the intensive care unit: An analysis of 22 cases. Crit Care Med 28: 377–382

    Article  PubMed  CAS  Google Scholar 

  24. Geha DJ, Roberts GD (1994) Laboratory detection of fungemia. Clin Lab Med 14: 83–97

    PubMed  CAS  Google Scholar 

  25. Niederman MS, Torres A, Summer W (1994) Invasive diagnosis testing is not needed routinely to manage suspected ventilator-associated pneumonia. Am J Respir Crit Care Med 150: 565–574

    Article  PubMed  CAS  Google Scholar 

  26. Goldman L (1986) Autopsy: seventy-five years after Gabot. J Am Geriatr Soc 34: 897–898

    PubMed  CAS  Google Scholar 

  27. Dimopoulos G, Piagnerelli M, Berrè J, Salmon I, Vincent JL (2000) Post mortem examination in the ICU. Still useful? Crit Care Med 28:78 a (Abst)

    Article  Google Scholar 

  28. Ahronheim JC, Bernholc AS, Clark WD (1983) Age trends in autopsy rates: striking decline in late life. JAMA 250: 1182–1186

    Article  PubMed  CAS  Google Scholar 

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Dimopoulos, G. (2002). Are Autopsies still Useful in the Intensive Care Unit?. In: Vincent, JL. (eds) Intensive Care Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-5551-0_84

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  • DOI: https://doi.org/10.1007/978-1-4757-5551-0_84

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4757-5553-4

  • Online ISBN: 978-1-4757-5551-0

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