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Molecular Cloning and Expression of Angiotensin II Type 2 Receptor Gene

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Recent Advances in Cellular and Molecular Aspects of Angiotensin Receptors

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 396))

Abstract

Angiotensin II (Ang II) has been known as one of potent vasoactive peptides which also regulates fluid homeostasis, blood pressure, drinking behavior, aldosterone release, peripheral norepinephrine release, cell proliferation and hypertrophy (1–3). These diversity of specific physiological effects of Ang II has suggested possible presence of subtypes of Ang II receptor. While the recognition of reducing agent-sensitive and -insensitive Ang II receptors had suggested the possibility of multiple subtypes (4), the question remained unresolved until the development of new peptide and non-peptidic antagonists of the Ang II receptor (5–7). These compounds turned out to be isoform specific and powerful tools for the characterization and isolation of the Ang II receptors and receptor genes.

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Authors and Affiliations

  1. Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee, 37232, USA

    Toshihiro Ichiki, Yoshikazu Kambayashi & Tadashi Inagami

Authors
  1. Toshihiro Ichiki
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  2. Yoshikazu Kambayashi
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  3. Tadashi Inagami
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Editors and Affiliations

  1. University of Florida, Gainesville, Florida, USA

    Mohan K. Raizada , M. Ian Phillips  & Colin Sumners ,  & 

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© 1996 Springer Science+Business Media New York

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Ichiki, T., Kambayashi, Y., Inagami, T. (1996). Molecular Cloning and Expression of Angiotensin II Type 2 Receptor Gene. In: Raizada, M.K., Phillips, M.I., Sumners, C. (eds) Recent Advances in Cellular and Molecular Aspects of Angiotensin Receptors. Advances in Experimental Medicine and Biology, vol 396. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1376-0_15

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  • DOI: https://doi.org/10.1007/978-1-4899-1376-0_15

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1378-4

  • Online ISBN: 978-1-4899-1376-0

  • eBook Packages: Springer Book Archive

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