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Four Acetylcholinesterase Genes in the Nematode Caenorhabditis Elegans

I. Ace-1 and Ace-2

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Structure and Function of Cholinesterases and Related Proteins

Abstract

It was previously reported that three genes, ace-1, ace-2 and ace-3 encode three pharmacological classes of acetylcholinesterase (AChE) in the nematode Caenorhabditis elegans [1]. ace-1 was first cloned and characterized [2] but a partial sequence of three other ace genes ace-2, ace-x and ace-y were recently reported [3]. We are interested in the function of each AChE class and in the regulation of their expression during development.

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References

  1. Johnson, C.J. (1991) In Cholinesterases. ASC Conference series, 136-140.

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  2. Arpagaus, M., Fedon, Y., Cousin, X., Chatonnet, A., Bergé, J.-B., Fournier, D. and Toutant, J.-P. (1994) J. Biol. Chem. 269, 9957–9965.

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  3. Grauso, M., Culetto, E., Combes, D., Fedon, Y., Toutant, J.-P. and Arpagaus, M. (1998) FEBS Lett., submitted.

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  4. Culotti, J.G., Von Ehrenstein, G., Culotti, M.R. and Russell, R.L. (1981) Genetics 97, 281–305.

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© 1998 Springer Science+Business Media New York

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Combes, D. et al. (1998). Four Acetylcholinesterase Genes in the Nematode Caenorhabditis Elegans . In: Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. (eds) Structure and Function of Cholinesterases and Related Proteins. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1540-5_31

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  • DOI: https://doi.org/10.1007/978-1-4899-1540-5_31

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1542-9

  • Online ISBN: 978-1-4899-1540-5

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