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Bioactive Natural Products from Traditionally used Mexican Plants

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Phytochemistry of Medicinal Plants

Part of the book series: Recent Advances in Phytochemistry ((RAPT,volume 29))

Abstract

Drug discovery based on the investigation of terrestrial plants for their therapeutic potential has been a goal of mankind since prehistoric times and is a universal feature of human cultures. Traditional methods of trial and error and use of lepto-organic and taxonomic clues have now given way to modern phytochemical and pharmacological methods for drug development. Plant derived natural products are a source of economically important chemicals, clinically useful drugs, leads for synthesis of derivatives and analogues and tools for biochemical investigations of mamalian receptors. They can also be useful “over the counter” remedies for self administration, and therefore could represent effective strategies of health assistance programmes in developing countries.

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References

  1. Mata, R. 1993. Chemical studies and biological aspects of some Mexican plants used in traditional medicine. In: Phytochemical Potential of Tropical Plants. (K. R. Downum, J. T. Romeo, H. A. Stafford, eds.). Plenum Press, New York. pp. 41–64.

    Chapter  Google Scholar 

  2. Ramamoorthy, T. P., Elliott, M. 1993. Mexican Lamiaceae: Diversity, distribution, endemism, and evolution. In: Biological Diversity of Mexico: Origins and Distribution. (T. P. Ramamoorthy, R. Bye, A. Lot, J. Fa, eds.), Oxford University Press, New York, pp. 513–539.

    Google Scholar 

  3. Wagner, H. 1977. Pharmaceutical and economic use of the Labiatae and Rutaceae families. Rev. Latinoamer. Quim. 8: 16–25.

    CAS  Google Scholar 

  4. Lawrence, B. M. 1992. Chemical components of Labiatae oils and their exploitation. In: Advances in Labiatae Science. (R.M. Harley, T. Reynolds, eds.), Royal Botanic Gardens, Kew, pp. 399–436.

    Google Scholar 

  5. Linares, E., Bye, R., Flores, B. 1984. Tés curativos de México. Fonart/SEP-Cultura, México, pp. 1–95.

    Google Scholar 

  6. Heinrich, M. 1992. Economic Botany of American Labiatae. In: Advances in Labiatae Science. (R.M. Harley, T. Reynolds, eds.), Royal Botanic Gardens, Kew, pp. 475–488.

    Google Scholar 

  7. Alcorn, J. B. 1984. Huastec Mayan Ethnobotany. University of Texas Press, Austin. p. 982.

    Google Scholar 

  8. Heinrich, M., Rimpler, H. Barrera, N. A. 1992. Indigenous phytotherapy of gastrointestinal disorders in a lowland Mixe community (Oaxaca, Mexico): Ethnopharmacologic evaluation. J. Ethnopharmacol. 36: 63–80.

    Article  PubMed  CAS  Google Scholar 

  9. Hernandez, F. 1942. Historia de las Plantas de Nueva España por Francisco Hernández, Médico e Historiador de su Majestad don Felipe II, Rey de España y de la Indias, y Protomédico de Todo el Nuevo Mundo. Instituto de Biologia, Universidad Nacional Autónoma de México, México. Vol. 1. p. 318.

    Google Scholar 

  10. Hernandez, F. 1959. Obras Complétas. Historia Natural de Nueva España I. Universidad Nacional Autónoma de México, México, vol. II. p. 397.

    Google Scholar 

  11. Navarro, J. 1992. Historia Natural o Jardin Americano (Manuscrito de 1801). Unam-Imss-Issste, México. p. 112.

    Google Scholar 

  12. Hernandez, F. 1984. Obras Completas. Comentarios a la Obra de Francisco Hernández. Universidad Nacional Autónoma de México, México, vol. VII. p. 187.

    Google Scholar 

  13. Epling, C. 1949. Revisión del género Hyptis (Labiatae). Revista del Museo de la Plata 8: 153–497.

    Google Scholar 

  14. Martinez, M. 1979. Catálogo de Nombres Vulgares y Científicos de Plantas Mexicanas. Fondo de Cultura Económica, México, pp. 1133–1134.

    Google Scholar 

  15. Pereda-Miranda, R., Delgado, G. 1990. Triterpenoids and flavonoids from Hyptis albida. J. Nat. Prod. 53: 182–185.

    Article  CAS  Google Scholar 

  16. Martinez, M. 1989. Las Plantas Medicinales de México. 6th éd. Ed. Botas, México, pp. 412–488.

    Google Scholar 

  17. Reis Altschul, S. von. 1973. Drugs and Foods from Little-Known Plants. Notes in Harvard University Herbaria. Harvard University Press, Cambridge, pp. 263–265.

    Google Scholar 

  18. Pereda-Miranda, R., Gascon-Figueroa, M. 1988. Chemistry of Hyptis mutabilis: New pentacyclic triterpenoids. J. Nat. Prod. 51: 996–998.

    Article  PubMed  CAS  Google Scholar 

  19. Pereda-Miranda, R., Hernandez, L., Villavicencio, M. J., Novelo, M., Ibarra, P., Chai, H., Pezzuto, J. M. 1993. Structure and stereochemistry of pectinolides A-C, novel antimicrobial and cytotoxic 5,6-dihydro-α-pyrones from Hyptis pectinata. J. Nat. Prod. 56: 583–593.

    Article  PubMed  CAS  Google Scholar 

  20. Roig Y Mesa, J. T. 1974. Plantas Medicinales, Aromáticas o Venenosas de Cuba. Instituto de Libro, La Habana, Cuba, pp. 596–597.

    Google Scholar 

  21. Del Amo, R. S. 1979. Plantas Medicinales del Estado de Veracruz. Instituto Nacional de Investigaciones sobre Recursos Bióticos, México. p. 110.

    Google Scholar 

  22. Soto Nuñez, J. C. 1987. Las Plantas Medicinales y su Uso Tradicional en la Cuenca del Rio Balsas; Estados de Michoacán y Guerrero, México. B.S. Thesis. Universidad Nacional Autónoma de México, México. p. 56.

    Google Scholar 

  23. Novelo, M., Cruz, J. G., Hernandez, L., Pereda-Miranda, R., Chai, H., Mar, W., Pezzuto, J. M. 1993. Cytotoxic constituents from Hyptis verticillata. J. Nat. Prod. 56: 1728–1736.

    Article  PubMed  CAS  Google Scholar 

  24. Martinez Alfaro, M. A. 1984. Medicinal plants used in a Totonac community of the Sierra Norte de Puebla: Tuzamapan de Galeana, Puebla, México. J. Ethnopharmacol. 11: 203–221.

    Article  PubMed  CAS  Google Scholar 

  25. Heinrich, M., Velazco, O., Ramos, F. 1990. Ethnobotanical report on the treatment of snake-bites in Oaxaca, Mexico. Curare 13: 11–16.

    Google Scholar 

  26. Arnason, T., Uck, F., Lambert, J., Hebda, R. 1980. Maya medicinal plants of San Jose Succotz, Belize. J. Ethnopharmacol. 2: 345–364.

    Article  PubMed  CAS  Google Scholar 

  27. Mitscher, L. A., Drake, S., Gollapudi, S. R., Okwute, S. K. 1987. A modern look at folkloric use of anti-infective agents. J. Nat. Prod. 50: 1025–1040.

    Article  PubMed  CAS  Google Scholar 

  28. Rojas, A., Hernandez, L., Pereda-Miranda, R., Mata, R. 1992. Screening for antimicrobial activity of crude drug extracts and pure natural products from Mexican medicinal plants. J. Ethnopharmacol. 35: 275–283.

    Article  PubMed  CAS  Google Scholar 

  29. Pereda-Miranda, R., Ibarra, P., Hernandez, L., Novelo, M. 1990. Bioactive constituents from Hyptis species. Planta Medica 56: 560–561.

    Article  Google Scholar 

  30. Kingston, D. G. I., Rao, M. M., Zucker, W. V. 1979. Plant Anticancer Agents. Ix. Constituents of Hyptis tomentosa. J. Nat. Prod. 42: 496–499.

    Article  PubMed  CAS  Google Scholar 

  31. Sheth, K., Jolad, S., Wiedhopf, R., Cole, J. R. 1972. Tumor-inhibitory agent from Hyptis emoryi (Labiatae). J. Pharm. Sci. 61:1819.

    Article  PubMed  CAS  Google Scholar 

  32. Pereda-Miranda, R., Hernandez, L., Lopez, R. 1992. A novel abietane-type diterpene from Salvia albocaerulea. Planta Medica 58: 223–224.

    Article  PubMed  CAS  Google Scholar 

  33. Davies-Coleman, M. T., Rivett, D. E. A. 1989. Naturally occurring 6-substituted 5,6-dihydro-α-pyrones. In: Progress in the Chemistry of Organic Natural Products. (W. Herz, H. Grisebach, G. W. Kirby, C. Tamm, eds.), Springer-Verlag, New York. Fortschr. Chem. organ. Naturstoffe pp. 1–35.

    Google Scholar 

  34. Pereda-Miranda, R., Garcia, M., Delgado, G. 1990. Structure and stereochemistry of four α-pyrones from Hyptis oblongifolia. Phytochemistry 29: 2971–2974.

    Article  CAS  Google Scholar 

  35. German, V. F. 1971. Isolation and characterization of cytotoxic principles from Hyptis verticillata Jacq. J. Pharm. Sci. 60: 649–650.

    Article  PubMed  CAS  Google Scholar 

  36. Sam, T. W. 1993. Toxicity testing using the brine shrimp: Artemia salina. In: Bioactive Natural Products. Detection, Isolation, and Structural Determination. (S. M. Colegate, R. J. Molyneux, eds.), Crc Press, Boca Raton, Florida, pp. 441–456.

    Google Scholar 

  37. Ayres, D. C., Loike, J. D. 1990. Lignans. Chemical, Biological and Clinical Properties. Cambridge University Press, Great Britain, pp. 85–112.

    Book  Google Scholar 

  38. Wagner, H. 1973. The chemistry of resin glycosides of the Convolvulaceae family. In: Medicine and Natural Sciences, Chemistry in Botanical Classification. (G. Bendz, J. Santesson, eds.), Academic Press, New York, pp. 235–240.

    Google Scholar 

  39. Linajes, A., Rico-Gray, V., Carrion, G. 1994. Traditional production system of the root of jalap, Ipomoea purga (Convolvulaceae), in Central Vercruz, Mexico. Economic Bot. 48: 84–89.

    Article  Google Scholar 

  40. Castro Ramirez, A. E. 1988. Estudio Comparativo del Conocimiento sobre Plantas Medicinales Utilizadas por Dos Grupos Etnicos del Muncipio de Pahuatlán, Puebla. San Juan Iztacala, México. B.S. Thesis. Escuela Nacional de Estudios Profesionales Iztacala. Universidad Nacional Autónoma de México, pp. 60-61.

    Google Scholar 

  41. Diaz, J. L. 1976. Usos de las Plantas Medicinales de México. Monografías Cientificas II. Instituto Mexicano para el Estudio de las Plantas Medicinales, A.C., México, pp. 66–67.

    Google Scholar 

  42. Beutler, J. A., Alvarado, A. B., McCloud, T. G., Cragg, G. M. 1989. Distribution of phorbol ester bioactivity in the Euphorbiaceae. Phytother. Res. 3: 188–192.

    Article  CAS  Google Scholar 

  43. Evans, F. J. 1991. Natural products as probes for new drug target identification. J. Ethnopharmacol. 32: 91–101.

    Article  PubMed  CAS  Google Scholar 

  44. Noda, N., Kogetsu, H., Kawasaki, T., Miyahara, K. 1990. Scamonins I and II, the resin glycosides of radix scammoniae from Convolvulus scammonia. Phytochemistry 29: 3565–3569.

    Article  PubMed  CAS  Google Scholar 

  45. Pereda-Miranda, R., Mata, R., Anaya, A. L., Wickramaratne, D. B., Pez-Zuto, J. M., Kinghorn, A. D. 1993. Tricolorin A, major phytogrowth inhibitor from Ipomoea tricolor. J. Nat. Prod. 56: 571–582.

    Article  PubMed  CAS  Google Scholar 

  46. Peterson, J. K., Harrison H. F., Jr. 1991. Isolation of substance from sweet potato (Ipomoea batatas) periderm tissue that inhibits seed germination. J. Chem. Ecol. 17: 943–951.

    Article  CAS  Google Scholar 

  47. Bah, M., Bye, R., Pereda-Miranda., R. 1994. Hepatotoxic pyrrolizidine alkaloids in the Mexican medicinal plant Packera candidissima (Asteraceae: Senecioneae). J. Ethnopharmacol. 43: 19–30.

    Article  PubMed  CAS  Google Scholar 

  48. Zalkow, L. H., Asibal, C. F., Glinski, J. A., Bonetti, S. J., Gelbaum, L. T., Vanderveer, D., Powis, G. 1988. Macrocyclic pyrrolizidine alkaloids from Senecio anonymus. Separation of a complex alkaloid extract using droplet counter-current chromatography. J. Nat. Prod. 51: 690–702.

    Article  PubMed  CAS  Google Scholar 

  49. Bohlmann, F., Zdero, C., King, R. M., Robinson, H. 1981. The first acetylenic monoterpene and other constituents from Senecio clevelandii. Phytochemistry 20: 2425–2427.

    Article  CAS  Google Scholar 

  50. McCoy, J. W., Roby, M. R., Stermitz, F. R. 1983. Analysis of plant alkaloid mixtures by ammonia chemical ionization mass spectrometry. J. Nat. Prod. 46: 894–900.

    Article  CAS  Google Scholar 

  51. Perez, A. L., Vidales, P., Cardenas, J., Romo De Vivar, A. 1991. Eremophilanolides from Senecio toluccanus var. modestus. Phytochemistry 30: 905–908.

    Article  CAS  Google Scholar 

  52. Huxtable, R J. 1989. Human health implications of pyrrolizidine alkaloids and herbs containing them. In: Toxicants of Plant Origen. Alkaloids, Vol. I. (P. R. Cheeke, ed.), Crc Press, Boca Raton, FL. pp. 41–86.

    Google Scholar 

  53. Mattocks, A. R. 1986. Chemistry and Toxicology of Pyrrolidine Alkaloids. Academic Press, London, pp. 158–315.

    Google Scholar 

  54. Hartwell, J. L. 1968. Plants used against cancer. A survey. Lloydia 31:71–170.

    Google Scholar 

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Pereda-Miranda, R. (1995). Bioactive Natural Products from Traditionally used Mexican Plants. In: Arnason, J.T., Mata, R., Romeo, J.T. (eds) Phytochemistry of Medicinal Plants. Recent Advances in Phytochemistry, vol 29. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1778-2_5

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  • DOI: https://doi.org/10.1007/978-1-4899-1778-2_5

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