Abstract
The synthesis of haem is obligatory for all aerobic cells because of the importance of this prosthetic group for a variety of metabolic processes. It is an iron-chelated tetrapyrrole that facilitates electron-transfer reactions vital for energy exchange and also catalyses the introduction of molecular oxygen into a broad range of endogenous and exogenous substrates which assists in diminishing their biological activity and enhancing their rate of excretion from the body.
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References
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Bickers, D.R. (1990). Porphyrias. In: Wojnarowska, F., Briggaman, R.A. (eds) Management of Blistering Diseases. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-7190-6_19
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