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Part of the book series: Contemporary Clinical Neuroscience ((CCNE))

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Abstract

Alzheimer’s disease (AD) is the most common cause of dementia and can be thought of as a prototype of a primary neurodegenerative disorder (1,2). Studies of the epidemiology of AD have demonstrated an age-related increase in prevalence from approximately 10% in persons 65 yr old to as high as 50% in persons reaching 85 yr of age (3). In addition to age, family history, head trauma, general anesthesia, and a poor education have been implicated as risk factors for AD (4–6). The “graying” of our society as well as successes in developing treatments for other chronic disorders implies that unless ways are found to reduce the incidence of AD, the societal costs attributable to AD will increase in the coming years. The public health problem posed by AD is succintly illustrated by the fact that the current annual cost associated with AD in the United States is approximately US $100 billion. The projected quadupling of the affected population in the next 20–30 yr (7) serves to underscore the scope of the challenge.

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Gold, M., Felsenstein, K.M., Molinoff, P. (2001). Treatment Approaches for Alzheimer’s Disease. In: Molecular Mechanisms of Neurodegenerative Diseases. Contemporary Clinical Neuroscience. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-006-3_6

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  • DOI: https://doi.org/10.1007/978-1-59259-006-3_6

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61737-197-4

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