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Photon- and Proton-Beam Radiotherapy in the Treatment of Spine Tumors

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Cancer in the Spine

Part of the book series: Current Clinical Oncology ((CCO))

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Abstract

Over the last 30 yr, the treatment of primary and metastatic tumors of the cervical, thoracic, and lumbar spine has evolved dramatically. In the case of primary tumors of the spine, advances in neoadjuvant treatments and instrumentation techniques have offered patients with previously inoperable disease new options with reasonable chances of cure. When the overall morbidity of radical resection makes it a poor treatment option, radiation therapy can be combined with more conservative surgical procedures or can be used in lieu of surgery for palliation, or even cure in some instances. With new advances in radiotherapy techniques, greater doses of radiation (often tumorocidal doses) can be administered to the majority of tumor volume with fewer effects on the surrounding structures and, most particularly, minimal risk to the spinal cord. It is imperative for the clinician and surgeon to be familiar with these new techniques so that the care of their patients can be optimized, with the highest potential for long-term survival and reduced morbidity.

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Author information

Authors and Affiliations

  1. Department of Radiation Oncology, Harvard Medical School, Boston, MA

    Thomas F. Delaney MD

  2. Department of Radiation Oncology, Northeast Proton Therapy Center, Massachusetts General Hospital, Boston, MA

    Thomas F. Delaney MD

  3. Arthritis Institute, Centinela-Freeman Medical Center, Inglewood, CA

    Michael J. Harris MD

  4. Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital and Department of Orthopedic Surgery, Harvard Medical School, Boston, MA

    Francis J. Hornicek MD, PhD

  5. Lerner College of Medicine and The Cleveland Clinic Spine Institute, Department of Orthopaedic Surgery, The Cleveland Clinic Foundation, Cleveland, OH

    Robert F. Mclain MD

Authors
  1. Thomas F. Delaney MD
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  2. Michael J. Harris MD
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  3. Francis J. Hornicek MD, PhD
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  4. Robert F. Mclain MD
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Editor information

Editors and Affiliations

  1. Lerner College of Medicine and The Cleveland Clinic Spine Institute Department of Orthopaedic Surgery, The Cleveland Clinic Foundation, Cleveland, OH

    Robert F. McLain MD

  2. The Cleveland Clinic Spine Institute, The Cleveland Clinic Foundation, Cleveland, OH

    Kai-Uwe Lewandrowski MD  & Edward C. Benzel MD, FACS  & 

  3. University of Texas M. D. Anderson Cancer Center, Houston, TX

    Maurie Markman MD

  4. Taussig Cancer Center, The Cleveland Clinic Foundation, Cleveland, OH

    Ronald M. Bukowski MD

  5. Department of Radiation Oncology, The Cleveland Clinic Foundation, Cleveland, OH

    Roger Macklis MD

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© 2006 Humana Press, Inc., Totowa, NJ

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Delaney, T.F., Harris, M.J., Hornicek, F.J., Mclain, R.F. (2006). Photon- and Proton-Beam Radiotherapy in the Treatment of Spine Tumors. In: McLain, R.F., Lewandrowski, KU., Markman, M., Bukowski, R.M., Macklis, R., Benzel, E.C. (eds) Cancer in the Spine. Current Clinical Oncology. Humana Press. https://doi.org/10.1007/978-1-59259-971-4_25

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  • DOI: https://doi.org/10.1007/978-1-59259-971-4_25

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-074-8

  • Online ISBN: 978-1-59259-971-4

  • eBook Packages: MedicineMedicine (R0)

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