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Spinal Cord and Nerve Root Decompression

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Cancer in the Spine

Part of the book series: Current Clinical Oncology ((CCO))

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Abstract

Tumors of the vertebral column include both primary and metastatic lesions. These tumors can cause significant morbidity consisting of lesional pain and pain from deformity. Compression of the spinal cord and spinal nerve roots can also cause radicular pain as well as neurologial deterioration including sensory deficits, weakness, paralysis, and/or sexual/bowel/ bladder dysfunction. In cases of metastatic lesions, the spine is the most common region of osseous involvement (1). Metastatic vertebral spine lesions can result in pathological fractures or have significant epidural tumor involvement, both of which can lead to neurological deterioration (2). Mortality and morbidity can be significant in malignant tumors and overall treatment is best addressed by a multidisciplinary approach.

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Authors and Affiliations

  1. Department of Neurosurgery, University of Michigan School of Medicine, Ann Arbor, MI

    Keith R. Lodhia MD, MS & Paul Park MD

  2. Department of Orthopaedic Surgery, University of Michigan School of Medicine, Ann Arbor, MI

    Gregory P. Graziano MD

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  1. Keith R. Lodhia MD, MS
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  2. Paul Park MD
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  3. Gregory P. Graziano MD
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Editors and Affiliations

  1. Lerner College of Medicine and The Cleveland Clinic Spine Institute Department of Orthopaedic Surgery, The Cleveland Clinic Foundation, Cleveland, OH

    Robert F. McLain MD

  2. The Cleveland Clinic Spine Institute, The Cleveland Clinic Foundation, Cleveland, OH

    Kai-Uwe Lewandrowski MD  & Edward C. Benzel MD, FACS  & 

  3. University of Texas M. D. Anderson Cancer Center, Houston, TX

    Maurie Markman MD

  4. Taussig Cancer Center, The Cleveland Clinic Foundation, Cleveland, OH

    Ronald M. Bukowski MD

  5. Department of Radiation Oncology, The Cleveland Clinic Foundation, Cleveland, OH

    Roger Macklis MD

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© 2006 Humana Press, Inc., Totowa, NJ

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Lodhia, K.R., Park, P., Graziano, G.P. (2006). Spinal Cord and Nerve Root Decompression. In: McLain, R.F., Lewandrowski, KU., Markman, M., Bukowski, R.M., Macklis, R., Benzel, E.C. (eds) Cancer in the Spine. Current Clinical Oncology. Humana Press. https://doi.org/10.1007/978-1-59259-971-4_29

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