Abstract
Cryoglobulinemia (CG) is a systemic inflammatory syndrome that generally involves small to medium vessel vasculitis because of cryoglobulin-containing immune complexes. It is now recognized that the majority of clinically significant CG have concurrent chronic hepatitis C virus (HCV) infection. Ineffective immune response to HCV has been hypothesized as a culprit. Clinical course of CG, however, is protean, and successful treatment of HCV does not guarantee resolution of CG. The role of HCV in the pathogenesis of CG and basis for its current treatment practice are discussed here.
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© 2008 Humana Press, a part of Springer Science+Business Media, LLC
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Seo, S., Török, N.J. (2008). Cryoglobulinemic Syndrome. In: Shoenfeld, Y., Cervera, R., Gershwin, M.E. (eds) Diagnostic Criteria in Autoimmune Diseases. Humana Press. https://doi.org/10.1007/978-1-60327-285-8_27
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DOI: https://doi.org/10.1007/978-1-60327-285-8_27
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