Abstract
Clinical research is an information and resource intensive endeavor, incorporating a broad variety of stakeholders spanning a spectrum from patients to providers to policymakers. Increasingly, the modern clinical research environment incorporates a number of informatics methods and technologies, informed by sociotechnical and information-theoretic frameworks. In this chapter, we introduce the major facets that serve to define the clinical research setting, including the design of clinical studies, clinical research workflow, and information management needs incumbent to such activities. Throughout this review, we will provide a number of exemplary linkages to core biomedical informatics challenges and opportunities and the foundational theories and frameworks underlying such issues. Finally, this chapter places the preceding review in the context of a number of national-scale initiatives that seek to address such needs and requirements.
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Payne, P.R.O. (2012). The Clinical Research Environment. In: Richesson, R., Andrews, J. (eds) Clinical Research Informatics. Health Informatics. Springer, London. https://doi.org/10.1007/978-1-84882-448-5_3
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