Abstract
Increase of breast cancer diagnosis especially of T1 tumors (over 60 % in 1990), decrease of N+ cancers (65 % in 1970, 45 % in 1990), the fact that we know that 30 % patients with N- cancers will metastase within 5 years after the diagnosis do modify indeed our appreciation of classical prognostic factors and especially of the importance of lymphnode involvement. The histoprognostic grade described by Scarff-Bloom and Richardson (SBR) keeps its value despite the large proportion of SBRII which have no specific predictive value [1]. Le Doussal and al [2] showed that SBR (modified SBR) influenced metastasis free survival of N-patients and allowed to recognize low risk and high risk categories.
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References
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© 1994 Springer-Verlag France
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de Maublanc, M.A. (1994). Breast cancer, cytoprognostic grades and proliferative activity (DNA ploidy, S phase). In: Banzet, P., Holland, J.F., Khayat, D., Weil, M. (eds) Cancer Treatment An Update. Springer, Paris. https://doi.org/10.1007/978-2-8178-0765-2_20
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DOI: https://doi.org/10.1007/978-2-8178-0765-2_20
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