Abstract
The changes that happen as an intrinsic part of aging occur deeper in the subcutaneous tissues and are atrophic in nature (Donofrio, Dermatol Surg 26:1129–1134, 2000). This volume loss can be corrected through several means, including tissue repositioning, implants, synthetic fillers, or autologous tissue (Modarressi, World J Plast Surg 2(1):6–13, 2013). More recently, autologous fat grafting has come to be considered an ideal filler, as fat grafts are biocompatible, nonallergenic, nontoxic, easy to obtain, and synergistic with natural skin (Sinno et al. Plast Reconstr Surg 137:818–824, 2016). Neuber first reported the technique in 1893, followed by Illouz who then pioneered liposuction in the 1980s. In the modern day, Coleman demonstrated techniques for long-term fat graft stability (Sinno et al. Plast Reconstr Surg 137:818–824, 2016). Its first indications were for aesthetic surgery of the face, and more recently in hands (Modarressi, World J Plast Surg 2(1):6–13, 2013). Fat grafting is also useful for tissue loss due to an accident, operation, congenital disease, or lipodystrophy. In addition to a volumizing effect, the injected fat leads to neoangiogenesis, thereby improving the cutaneous elasticity. This technique is also used for wound healing, scar reduction, treatment of radiodermatitis, correction of acne scars, and breast reconstruction and augmentation in plastic surgery (Modarressi, World J Plast Surg 2(1):6–13, 2013).
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Ellis, D.L., Donofrio, L.M. (2019). Fat Transplantation. In: Alam, M. (eds) Evidence-Based Procedural Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-030-02023-1_37
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