Abstract
Nanomaterials with unique optical properties and biocompatibility have been widely employed for designing and fabricating highly selective and sensitive nanosensors for the detection of various chemical and biological species. The development of nanomaterial-based chemo- and biosensors is studied usually under direct spectroscopic and reagent-mediated sensor platforms using both unmodified and surface-functionalized nanomaterials. This chapter mainly focuses on selective sensing of chemical and biological molecules using various types of nanomaterials. The main readouts are absorption (colorimetric, UV-visible), fluorescence, Raman/SERS spectroscopic, and electrochemical sensing techniques. The detailed discussion on the design of nanomaterial-based sensing systems, sensing principle, sensing method, and their signaling mechanisms has been provided. The sensing systems can also be ideally utilized for real-time applications.
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References
Anwar A, Minhaz A, Khan NA, Kalantari K, Afifi ABM, Shah MR (2018) Synthesis of gold nanoparticles stabilized by a pyrazinium thioacetate ligand: a new colorimetric nanosensor for detection of heavy metal Pd(II). Sensors Actuators B 257:875–881. https://doi.org/10.1016/j.snb.2017.11.040
Awual MR, Hasan MM, Naushad M et al (2015) Preparation of new class composite adsorbent for enhanced palladium(II) detection and recovery. Sensors Actuators B Chem 209:790–797. https://doi.org/10.1016/j.snb.2014.12.053
Bhattacharjee Y, Chakraborty A (2014) Label-free cysteamine-capped silver nanoparticle-based colorimetric assay for hg(ii) detection in water with subnanomolar exactitude. ACS Sustain Chem Eng 2:2149–2154. https://doi.org/10.1021/sc500339n
Borisov SM, Wolfbeis OS (2008) Optical biosensors. Chem Rev 108(2):423–461. https://doi.org/10.1021/cr068105t
Cao X, Shen F, Zhang M, Guo J, Luo Y, Xu J, Li Y, Sun C (2014) Highly sensitive detection of melamine based on fluorescence resonance energy transfer between rhodamine B and gold nanoparticles. Dyes Pigments 111:9–107. https://doi.org/10.1016/j.dyepig.2014.06.001
Chen B, Heng S, Peng H, Hu B, Yu X, Zhang Z, Pang D, Yue X, Zhu Y (2010) Magnetic solid phase microextraction on a microchip combined with electrothermal vaporization-inductively coupled plasma mass spectrometry for determination of Cd, Hg and Pb in cells. Anal At Spectrom 25:1931–1938. https://doi.org/10.1039/C0JA00003E
Chen S, Gao H, Shen W, Lu C, Yuan Q (2014) Colorimetric detection of cysteine using noncrosslinking aggregation of fluorosurfactant-capped silver nanoparticles. Sens Actuators B Chem 190:673–678. https://doi.org/10.1016/j.snb.2013.09.036
Cheng ML, Tsai BC, Yang J (2011) Silver nanoparticle-treated filter paper as a highly sensitive surface-enhanced Raman scattering (SERS) substrate for detection of tyrosine in aqueous solution. Anal Chim Acta 708(1–2):89–96. https://doi.org/10.1016/j.aca.2011.10.013
Cho HS, Lee B, Liu GL, Agarwal A, Lee LP (2009) Label-free and highly sensitive biomolecular detection using SERS and electrokinetic preconcentration. Lab Chip 9:3360–3363. https://doi.org/10.1039/B912076A
Dar RA, Khare NG, Cole DP, Karna SP, Srivastava AK (2014) Green synthesis of a silver nanoparticle–graphene oxide composite and its application for As(III) detection. RSC Adv 4:14432–14440. https://doi.org/10.1039/C4RA00934G
De Silva AP, Gunaratne HQN, Gunnlaugsson T, Huxley AJM, McCoy CP, Rademacher JT, Rice TE (1997) Signaling recognition events with fluorescent sensors and switches. Chem Rev 97(5):1515–1566. https://doi.org/10.1021/cr960386p
De Silva AP, Moody TS, Wright GD (2009) Fluorescent PET (photoinduced electron transfer) sensors as potent analytical tools. Analyst 134(12):2385–2393. https://doi.org/10.1039/b912527m
Descalzo AB, Rurack K, Weisshoff H, Martınez-Manez R, Marcos MD, Amoros P, Hoffmann K, Soto J (2005) Rational design of a chromo- and fluorogenic hybrid chemosensor material for the detection of long-chain carboxylates. J Am Chem Soc 127(1):184–200. https://doi.org/10.1021/ja045683n
Devi S, Pandian K (2014) Synthesis of chitosan protected nickel hexacyanoferrate modified titanium oxide nanotube and study its application on simultaneous s electrochemical detection of paracetamol and caffeine. Adv Mater Res 938(2014):192–198. https://doi.org/10.4028/www.scientific.net/AMR.938.192
Devi S, Devasena T, Saratha S, Tharmaraj P, Pandian K (2014) Dithiocarbamate post functionalized polypyrrole modified carbon sphere for the selective and sensitive detection of mercury by voltammetry method. Int J Electrochem Sci 9:670–683
Doleman L, Davies L, Rowe L, Moschou EA, Deo S, Daunert S (2007) Bioluminescence DNA hybridization assay for Plasmodium falciparum based on the photoprotein aequorin. Anal Chem 79(11):4149–4153. https://doi.org/10.1021/ac0702847
Dou Y, Yang X, Liu Z, Zhu S (2013) Homocysteine-functionalized silver nanoparticles for selective sensing of Cu2+ ions and lidocaine hydrochloride. Colloids Surf A Physicochem Eng Asp 423:20–26. https://doi.org/10.1016/j.colsurfa.2013.01.027
Fabbrizzi L, Poggi A (1995) Sensors and switches from supramolecular chemistry. Chem Soc Rev 24:197–202. https://doi.org/10.1039/CS9952400197
Farhadi K, Forougha M, Molaei R, Hajizadeha S, Rafipour A (2012) Highly selective Hg2+ colorimetric sensor using green synthesized and unmodified silver nanoparticles. Sensors Actuators B Chem 161:880–885. https://doi.org/10.1016/j.snb.2011.11.052
Feng J, Jin W, Huang P, Wu F (2017) Highly selective colorimetric detection of Ni2+ using silver nanoparticles cofunctionalized with adenosine monophosphate and sodium dodecyl sulfonate. J Nanopart Res 19:306. https://doi.org/10.1007/s11051-017-3998-0
Fernandez-Lopez C, Mateo-Mateo C, Alvarez-Puebla RA, Perez-Juste J, Pastoriza-Santos I, Liz-Marzan LM (2009) Highly controlled silica coating of PEG-capped metal nanoparticles and preparation of SERS-encoded particles. Langmuir 25(24):13894–13899. https://doi.org/10.1021/la9016454
Ferrando R, Jellinek J, Johnston RL (2008) Nanoalloys: from theory to applications of alloy clusters and nanoparticles. Chem Rev 108(3):845–910. https://doi.org/10.1021/cr040090g
Gao Y, Shi Z, Long Z, Wu P, Zheng C, Hou X (2012) Determination and speciation of mercury in environmental and biological samples by analytical atomic spectrometry. Microchem J 103:1–14. https://doi.org/10.1016/j.microc.2012.02.001
Gao YX, Xin JW, Shen ZY, Pan W, Li X, Wu AG (2013) A new rapid colorimetric detection method of Mn2+ based on tripolyphosphate modified silver nanoparticles. Sensors Actuators B 181:288–293. https://doi.org/10.1016/j.snb.2013.01.079
Guo S, Dong S, Wang E (2009a) A general route to construct diverse multifunctional Fe3O4/metal hybrid nanostructures. Chem Eur J 15(10):2416–2424. https://doi.org/10.1002/chem.200801942
Guo SJ, Li J, Ren W, Wen D, Dong SJ, Wang EK (2009b) Carbon nanotube/silica coaxial nanocable as a three-dimensional support for loading diverse ultra-high-density metal nanostructures: facile preparation and use as enhanced materials for electrochemical devices and SERS. Chem Mater 21(11):2247–2257. https://doi.org/10.1021/cm900300v
Han XX, Xie Y, Zhao B, Ozaki Y (2010) Highly sensitive protein concentration assay over a wide range via surface-enhanced Raman scattering of Coomassie brilliant blue. Anal Chem 82(11):4325–4328. https://doi.org/10.1021/ac100596u
Huynh WU, Dittmer JJ, Alivisatos AP (2002) Hybrid nanorod-polymer solar cells. Science 295(5564):2425–2427. https://doi.org/10.1126/science.1069156
Jia J, Wu A, Luan S (2014) Synthesis and investigation of the imprinting efficiency of ion imprinted nanoparticles for recognizing copper. Phys Chem Chem Phys 16:16158–16165. https://doi.org/10.1039/C4CP01858C
Jongjinakool S, Palasak K, Bousod N, Teepoo S (2014) Gold nanoparticles-based colorimetric sensor for cysteine detection. Energy Procedia 56:10–18. https://doi.org/10.1016/j.egypro.2014.07.126
Jung JH, Park M, Shinkai S (2010) Fabrication of silica nanotubes by using self-assembled gels and their applications in environmental and biological fields. Chem Soc Rev 39:4286–4302. https://doi.org/10.1039/C002959A
Kim HN, Guo Z, Zhu W, Yoon J, Tian H (2011) Recent progress on polymer-based fluorescent and colorimetric chemosensors. Chem Soc Rev 40:79–93. https://doi.org/10.1039/C0CS00058B
Kumar GVP, Shruthi S, Vibha B, Reddy BAA, Kundu TK, Narayana C (2007) Hot spots in Ag Core−Au shell nanoparticles potent for surface-enhanced Raman scattering studies of biomolecules. J Phys Chem C 111(11):4388–4392. https://doi.org/10.1021/jp068253n
Kumar A, Guo C, Sharma G et al (2016) Magnetically recoverable ZrO2/Fe3O4/chitosan nanomaterials for enhanced sunlight driven photoreduction of carcinogenic Cr(VI) and dechlorination & mineralization of 4-chlorophenol from simulated waste water. RSC Adv 6:13251–13263. https://doi.org/10.1039/C5RA23372K
Lian Y, Yuan M, Zhao H (2014) DNA wrapped metallic single-walled carbon nanotube sensor for Pb (II) detection. Fullerenes, Nanotubes, Carbon Nanostruct 22(5):510–518. https://doi.org/10.1080/1536383X.2012.690462
Liang CH, Wang CC, Lin YC, Chen CH, Wong CH, Wu CY (2009) Iron oxide/gold core/shell nanoparticles for ultrasensitive detection of carbohydrate−protein interactions. Anal Chem 81(18):7750–7756. https://doi.org/10.1021/ac9012286
Liu J, Zuo W, Zhang W, Liu J, Wang Z, Yang Z, Wang B (2014) Europium(III) complex-functionalized magnetic nanoparticle as a chemosensor for ultrasensitive detection and removal of copper(II) from aqueous solution. Nanoscale 6:11473–11478. https://doi.org/10.1039/C4NR03454F
Liu X, Na W, Qua Z, Su X (2016) Turn-off–on fluorescence probe based on 3-mercaptopropionic acid-capped CdS quantum dots for selective and sensitive lysozyme detection. RSC Adv 6:85795–85801. https://doi.org/10.1039/C6RA14420A
Lo SH, Wu MC, Wu SP (2015) A turn-on fluorescent sensor for cysteine based on BODIPY functionalized Au nanoparticles and its application in living cell imaging. Sensors Actuators B Chem 221:1366–1371. https://doi.org/10.1016/j.snb.2015.08.015
Mahshid S, Li C, Mahshid SS, Askari M, Dolati A, Yang L, Luo S, Cai Q (2011) Sensitive determination of dopamine in the presence of uric acid and ascorbic acid using TiO2 nanotubes modified with Pd, Pt and Au nanoparticles. Analyst 136(11):2322–2329. https://doi.org/10.1039/c1an15021a
Meenakshi S, Devi S, Pandian K, Devendiran R, Selvaraj M (2016) Sunlight assisted synthesis of silver nanoparticles in zeolite matrix and study of its application on electrochemical detection of dopamine and uric acid in urine samples. Mater Sci Eng C 69:85–94. https://doi.org/10.1016/j.msec.2016.06.037
Miao LJ, Xin JW, Shen ZY, Zhang YJ, Wang HY, Wu AG (2013) Exploring a new rapid colorimetric detection method of Cu2+ with high sensitivity and selectivity. Sensors Actuators B 176:906–912. https://doi.org/10.1016/j.snb.2012.10.070
Nguyen BT, Anslyn EV (2006) Indicator-displacement assays. Coord Chem Rev 250(23–24):3118–3127. https://doi.org/10.1016/j.ccr.2006.04.009
Ni P, Dai H, Li Z, Sun Y, Hu J, Jiang S, Wang Y, Li Z (2015) Carbon dots based fluorescent sensor for sensitive determination of hydroquinone. Talanta 144:258–262. https://doi.org/10.1016/j.talanta.2015.06.014
Nie SM, Emery SR (1997) Probing single molecules and single nanoparticles by surface-enhanced Raman scattering. Science 275(5303):1102–1106
Niu C, Liu Q, Shang Z, Zhaoa L, Ouyang J (2015) Dual-emission fluorescent sensor based on AIE organic nanoparticles and Au nanoclusters for the detection of mercury and melamine. Nanoscale 7:8457–8465. https://doi.org/10.1039/C5NR00554J
Nolan EM, Lippard SJ (2008) Tools and tactics for the optical detection of mercuric ion. Chem Rev 108(9):3443–3480. https://doi.org/10.1021/cr068000q
Noroozifar M, Khorasani-Motlagh M, Taheri A (2011) Determination of cyanide in wastewaters using modified glassy carbon electrode with immobilized silver hexacyanoferrate nanoparticles on multiwall carbon nanotube. J Hazard Mater 185(1):255–261. https://doi.org/10.1016/j.jhazmat.2010.09.02
Parnsubsakula A, Oaewb S, Surareungchai W (2018) Zwitterionic peptide-capped gold nanoparticles for colorimetric detection of Ni2+. Nanoscale 10:5466–5473. https://doi.org/10.1039/C7NR07998B
Pei LZ, Pei YQ, Xie YK, Fan CG, Yu HY (2013) Synthesis and characterization of manganese vanadate nanorods as glassy carbon electrode modified materials for the determination of L-cysteine. Cryst Eng Comm 15:1729–1738. https://doi.org/10.1039/C2CE26592C
Polavarapu L, Perez-Juste J, Xu QH, Liz-Marzan LM (2014) Optical sensing of biological, chemical and ionic species through aggregation of plasmonic nanoparticles. J Mater Chem C 2:7460–7476. https://doi.org/10.1039/C4TC01142B
Priyadarshini E, Pradhan N (2017) Metal-induced aggregation of valine capped gold nanoparticles: an efficient and rapid approach for colorimetric detection of Pb2+ ions. Sci Rep 7:9278. https://doi.org/10.1038/s41598-017-08847-5
Quang DT, Kim SJ (2010) Fluoro- and chromogenic chemodosimeters for heavy metal ion detection in solution and biospecimens. Chem Rev 110(10):6280–6301. https://doi.org/10.1021/cr100154p
Rajapandiyan P, Tang WL, Yang J (2011) Rapid detection of melamine in milk liquid and powder by surface-enhanced Raman scattering substrate array. Food Control 56:155–160. https://doi.org/10.1016/j.foodcont.2015.03.028
Rodriguez-Lorenzo L, Alvarez-Puebla RA, de Abajo FJG, Liz-Marzan LM (2010) Surface enhanced Raman scattering using star-shaped gold colloidal nanoparticles. J Phys Chem C 114(16):7336–7340. https://doi.org/10.1021/jp909253w
Sophia SJ, Devi S, Pandian K (2012) Electrocatalytic oxidation of hydrazine based on NiHCF@TiO2 core- shell nanoparticles modified GCE. Int J Electrochem Sci 7:6580–6598
Sujith A, Itoh T, Abe H, Yoshida KI, Kiran MS, Biju V, Ishikawa M (2009) Imaging the cell wall of living single yeast cells using surface-enhanced Raman spectroscopy. Anal Bioanal Chem 394(7):1803–1809. https://doi.org/10.1007/s00216-009-2883-9
Sung HK, Oh SY, Park C, Kim Y (2013) Colorimetric detection of Co2+ ion using silver nanoparticles with spherical, plate, and rod shapes. Langmuir 29:8978–8982. https://doi.org/10.1021/la401408f
Taton TA, Mirkin CA, Letsinger RL (2000) Scanometric DNA array detection with nanoparticle probes. Science 289(5485):1757–1760
Tharmaraj V, Jyisy Y (2014) Sensitive and selective colorimetric detection of Cu2+ in aqueous medium via aggregation of thiomalic acid functionalized Ag nanoparticles. Analyst 139:6304–6309. https://doi.org/10.1039/c4an01449a
Tharmaraj V, Pitchumani K (2011) Alginate stabilized silver nanocube–Rh6G composite as a highly selective mercury sensor in aqueous solution. Nanoscale 3:1166–1170. https://doi.org/10.1039/C0NR00749H
Tharmaraj V, Pitchumani K (2013) A highly selective ratiometric fluorescent chemosensor for Cu(II) based on dansyl-functionalized thiol stabilized silver nanoparticles. J Mater Chem B 1:1962–1967. https://doi.org/10.1039/C3TB00534H
Veiseh O, Gunn JW, Zhang MQ (2010) Design and fabrication of magnetic nanoparticles for targeted drug delivery and imaging. Adv Drug Deliv Rev 62(3):284–304. https://doi.org/10.1016/j.addr.2009.11.002
Vigano C, Ruysschaert JM, Goormaghtigh E (2005) Sensor applications of attenuated total reflection infrared spectroscopy. Talanta 65(5):1132–1142. https://doi.org/10.1016/j.talanta.2004.07.052
Wang F, Wang L, Chen X, Yoon J (2014) Recent progress in the development of fluorometric and colorimetric chemosensors for detection of cyanide ions. Chem Soc Rev 43:4312–4324. https://doi.org/10.1039/C4CS00008K
Wang G, Lu Y, Yan C, Lu Y (2015) DNA-functionalization gold nanoparticles based fluorescence sensor for sensitive detection of Hg2+ in aqueous solution. Sensors Actuators B Chem 211:1–6. https://doi.org/10.1016/j.snb.2015.01.051
Wen G, Lin C, Tang M, Liu G, Liang A, Jiang Z (2013) A highly sensitive aptamer method for Ag+ sensing using resonance Rayleigh scattering as the detection technique and a modified nanogold probe. RSC Adv 3:1941–1946. https://doi.org/10.1039/C2RA22542E
Wu X, Xu Y, Dong Y, Jiang X, Zhu N (2013) Colorimetric determination of hexavalent chromium with ascorbic acid capped silver nanoparticles. Anal Methods 5:560. https://doi.org/10.1039/c2ay25989c
Yang LB, Jiang X, Ruan WD, Zhao B, Xu WQ, Lombardi JR (2009) Adsorption study of 4-MBA on TiO2 nanoparticles by surface-enhanced Raman spectroscopy. J Raman Spectrosc 40:2004–2008. https://doi.org/10.1002/jrs.2358
Yu Y, Hong Y, Wang Y, Sun X, Liu B (2017) Mercaptosuccinic acid modified gold nanoparticles as colorimetric sensor for fast detection and simultaneous identification of Cr3+. Sensors Actuators B 239:865–873. https://doi.org/10.1016/j.snb.2016.08.043
Yuan X, Wen S, Shena M, Shi X (2013) Dendrimer-stabilized silver nanoparticles enable efficient colorimetric sensing of mercury ions in aqueous solution. Anal Methods 5:5486. https://doi.org/10.1039/c3ay41331d
Zhai D, Xu W, Zhang L, Chang YT (2014) The role of “disaggregation” in optical probe development. Chem Soc Rev 43:2402–2411. https://doi.org/10.1039/C3CS60368G
Zhan W, Bard AJ (2007) Electrogenerated chemiluminescence. Immunoassay of human C-reactive protein by using Ru(bpy)3 2+-encapsulated liposomes as labels. Anal Chem 79(2):459–463. https://doi.org/10.1021/ac061336f
Zhan S, Wu Y, He L, Wang F, Zhan X, Zhou P, Qiu S (2012) Measuring the size and density of nanoparticles by centrifugal sedimentation and flotation. Anal Methods 4:3997–4002. https://doi.org/10.1039/C8AY00237A
Zhang H, Jia Z (2017) Development of fluorescent FRET probes for “off-on” detection of L-cysteine based on gold nanoparticles and porous silicon nanoparticles in ethanol solution. Sensors 17(3):520. https://doi.org/10.3390/s17030520
Zhang WB, Su ZF, Chu XF, Yang XA (2010) Evaluation of a new electrolytic cold vapour generation system for mercury determination by AFS. Talanta 80(5):2106–2112. https://doi.org/10.1016/j.talanta.2009.11.016
Zheng Y, Huang Z, Zhao C, Weng S, Zheng W, Lin X (2013) A gold electrode with a flower-like gold nanostructure for simultaneous determination of dopamine and ascorbic acid. Microchim Acta 180(7–8):537–544. https://doi.org/10.1007/s00604-013-0964-0
Zhou Y, Xu Z, Yoon J (2011) Fluorescent and colorimetric chemosensors for detection of nucleotides, FAD and NADH: highlighted research during 2004–2010. Chem Soc Rev 40:2222–2235. https://doi.org/10.1039/C0CS00169D
Zoski CG (2007) Handbook of electrochemistry. Elsevier, Oxford
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Devi, S., Tharmaraj, V. (2019). Nanomaterials for Advanced Analytical Applications in Chemo- and Biosensors. In: Naushad, M., Rajendran, S., Gracia, F. (eds) Advanced Nanostructured Materials for Environmental Remediation. Environmental Chemistry for a Sustainable World, vol 25. Springer, Cham. https://doi.org/10.1007/978-3-030-04477-0_4
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