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Automatic Classification and Segmentation of Low-Grade Gliomas in Magnetic Resonance Imaging

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Proceedings of the Tenth International Conference on Soft Computing and Pattern Recognition (SoCPaR 2018) (SoCPaR 2018)

Part of the book series: Advances in Intelligent Systems and Computing ((AISC,volume 942))

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Abstract

In this article a new methodology is proposed to tackle the problem of automatic segmentation of low-grade gliomas. The possibility of knowing the limits of this type of tumor is crucial for effectively characterizing the neoplasm, enabling, in certain cases, to obtain useful information about how to treat the patient in a more effective way. Using a database of magnetic resonance images, containing several occurrences of this type of tumors, and through a carefully designed image processing pipeline, the purpose of this work is to accurately locate, isolate and thus facilitate the classification of the pathology. The proposed methodology, described in detail, was able to achieve an accuracy of 87.5% for a binary classification task. The quality of the identified regions had an accuracy of 81.6%. These are promising results that may point the effectiveness of the approach. The low contrast of the images, as a result of the acquisition process, and the detection of very small tumors are still challenges that bring motivation to further pursue additional results.

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References

  1. Gaspar, B.M.: Biomarcadores em gliomas: conhecimento atual e perspetivas futuras (2016). http://hdl.handle.net/10316/46899

  2. Louis, D.N., Perry, A., Reifenberger, G., von Deimling, A., Figarella-Branger, D., Cavenee, W.K., Ohgaki, H., Wiestler, O.D., Kleihues, P., Ellison, D.W.: The 2016 World Health Organization classification of tumors of the central nervous system: a summary. Acta Neuropathol. (Berl.) 131, 803–820 (2016)

    Article  Google Scholar 

  3. Forst, D.A., Nahed, B.V., Loeffler, J.S., Batchelor, T.T.: Low-grade gliomas. Oncologist. 19, 403–413 (2014)

    Article  Google Scholar 

  4. de Goulart, B.N.G., Chiari, B.M.: Testes de rastreamento x testes de diagnóstico: atualidades no contexto da atuação fonoaudiológica. Pró-Fono Rev. Atualização Científica 19, 223–232 (2007)

    Article  Google Scholar 

  5. Bø, H.K., Solheim, O., Jakola, A.S., Kvistad, K.-A., Reinertsen, I., Berntsen, E.M.: Intra-rater variability in low-grade glioma segmentation. J. Neurooncol. 131, 393–402 (2017)

    Article  Google Scholar 

  6. Guillevin, R., Herpe, G., Verdier, M., Guillevin, C.: Low-grade gliomas: the challenges of imaging. Diagn. Interv. Imaging 95, 957–963 (2014)

    Article  Google Scholar 

  7. Ostrom, Q.T., Gittleman, H., Xu, J., Kromer, C., Wolinsky, Y., Kruchko, C., Barnholtz-Sloan, J.S.: CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2009-2013. Neuro-Oncology 18, v1–v75 (2016)

    Article  Google Scholar 

  8. Gooya, A., Pohl, K.M., Bilello, M., Cirillo, L., Biros, G., Melhem, E.R., Davatzikos, C.: GLISTR: glioma image segmentation and registration. IEEE Trans. Med. Imaging 31, 1941–1954 (2012)

    Article  Google Scholar 

  9. Rathore, S., Bakas, S., Pati, S., Akbari, H., Kalarot, R., Sridharan, P., Rozycki, M., Bergman, M., Tunc, B., Verma, R., Bilello, M., Davatzikos, C.: Brain cancer imaging phenomics toolkit (brain-CaPTk): an interactive platform for quantitative analysis of glioblastoma. In: Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries, Third International Workshop, BrainLes 2017, Held in Conjunction MICCAI 2017, Quebec City, QC, Canada, 14 September 2017, Revised Selected Papers, vol. 10670, pp. 133–145 (2018)

    Chapter  Google Scholar 

  10. Bakas, S., Zeng, K., Sotiras, A., Rathore, S., Akbari, H., Gaonkar, B., Rozycki, M., Pati, S., Davatzikos, C.: GLISTRboost: combining multimodal MRI segmentation, registration, and biophysical tumor growth modeling with gradient boosting machines for glioma segmentation. In: Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries, First International Workshop, Brainles 2015, Held in Conjunction with MICCAI 2015, Munich, Germany, 5 October 2015, Revised Selected Papers, vol. 9556, pp. 144–155 (2016)

    Chapter  Google Scholar 

  11. Bakas, S., Akbari, H., Sotiras, A., Bilello, M., Rozycki, M., Kirby, J.S., Freymann, J.B., Farahani, K., Davatzikos, C.: Advancing the cancer genome atlas glioma MRI collections with expert segmentation labels and radiomic features. Sci. Data 4, 170117 (2017)

    Article  Google Scholar 

  12. Akkus, Z., Ali, I., Sedlář, J., Agrawal, J.P., Parney, I.F., Giannini, C., Erickson, B.J.: Predicting deletion of chromosomal arms 1p/19q in low-grade gliomas from MR images using machine intelligence. J. Digit. Imaging 30, 469–476 (2017)

    Article  Google Scholar 

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Correspondence to Luis Coelho .

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Barbosa, M., Moreira, P., Ribeiro, R., Coelho, L. (2020). Automatic Classification and Segmentation of Low-Grade Gliomas in Magnetic Resonance Imaging. In: Madureira, A., Abraham, A., Gandhi, N., Silva, C., Antunes, M. (eds) Proceedings of the Tenth International Conference on Soft Computing and Pattern Recognition (SoCPaR 2018). SoCPaR 2018. Advances in Intelligent Systems and Computing, vol 942. Springer, Cham. https://doi.org/10.1007/978-3-030-17065-3_5

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