Abstract
Neurological conditions affecting the larynx often coincide with respiratory issues, highlighting the importance of multispecialty care of these patients that includes pulmonologists. In this chapter, we provide a background on pulmonary evaluation and discuss several potential issues: Laryngeal dysfunction may mimic respiratory disease, with symptoms such as shortness of breath and abnormal airway sounds. In many diseases of the larynx, laryngeal dysfunction leads to a risk of pulmonary aspiration and pneumonia. In neuromuscular conditions, concurrent respiratory muscle weakness must be recognized for proper comprehensive care and perioperative evaluation. Increasingly, patients with respiratory muscle weakness are managed with noninvasive respiratory support including noninvasive ventilation and airway clearance modalities. In patients with severe laryngeal dysfunction, treatment including tracheostomy and possible mechanical ventilation (e.g., invasive approach) may still be warranted but should be evaluated with consideration of the patient’s values and preferences.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Wanger JS, Culver BH. Quality standards in pulmonary function testing: past, present, future. Ann Am Thorac Soc. 2016;13(9):1435–6.
Pellegrino R, Viegi G, Brusasco V, Crapo RO, Burgos F, Casaburi R, et al. Interpretative strategies for lung function tests. Eur Respir J. 2005;26(5):948–68.
Lutfi MF. The physiological basis and clinical significance of lung volume measurements. Multidiscip Respir Med. 2017;12(1):3.
Braun NM, Arora NS, Rochester DF. Respiratory muscle and pulmonary function in polymyositis and other proximal myopathies. Thorax. 1983;38(8):616–23.
Serisier DE, Mastaglia FL, Gibson GJ. Respiratory muscle function and ventilatory control. I n patients with motor neurone disease. II n patients with myotonic dystrophy. Q J Med. 1982;51(2):205–26.
Black LF, Hyatt RE. Maximal static respiratory pressures in generalized neuromuscular disease. Am Rev Respir Dis. 1971;103(5):641–50.
Kuzniar TJ, Morgenthaler TI, Prakash UB, Pallanch JF, Silber MH, Tippmann-Peikert M. Effects of continuous positive airway pressure on stridor in multiple system atrophy-sleep laryngoscopy. J Clin Sleep Med. 2009;5(1):65–7.
Miller RD, Hyatt RE. Evaluation of obstructing lesions of the trachea and larynx by flow-volume loops. Am Rev Respir Dis. 1973;108(3):475–81.
Rotman HH, Liss HP, Weg JG. Diagnosis of upper airway obstruction by pulmonary function testing. Chest. 1975;68(6):796–9.
Murry T, Cukier-Blaj S, Kelleher A, Malki KH. Laryngeal and respiratory patterns in patients with paradoxical vocal fold motion. Respir Med. 2011;105(12):1891–5.
Perkins MAJPJ, Morris LTCMJ. Vocal cord dysfunction induced by methacholine challenge testing. Chest. 2002;122(6):1988–93.
Guss J, Mirza N. Methacholine challenge testing in the diagnosis of paradoxical vocal fold motion. Laryngoscope. 2006;116(9):1558–61.
Christensen PM, Maltbaek N, Jorgensen IM, Nielsen KG. Can flow-volume loops be used to diagnose exercise induced laryngeal obstructions? A comparison study examining the accuracy and inter-rater agreement of flow volume loops as a diagnostic tool. Prim Care Respir J. 2013;22(3):306–11.
Marik PE. Aspiration pneumonitis and aspiration pneumonia. N Engl J Med. 2001;344(9):665–71.
Lee JS, Collard HR, Raghu G, Sweet MP, Hays SR, Campos GM, et al. Does chronic microaspiration cause idiopathic pulmonary fibrosis? Am J Med. 2010;123(4):304–11.
van der Graaff MM, Grolman W, Westermann EJ, Boogaardt HC, Koelman H, van der Kooi AJ, et al. Vocal cord dysfunction in amyotrophic lateral sclerosis: four cases and a review of the literaturevocal cord dysfunction in amyotrophic lateral sclerosis. Arch Neurol. 2009;66(11):1329–33.
Steier J, Kaul S, Seymour J, Jolley C, Rafferty G, Man W, et al. The value of multiple tests of respiratory muscle strength. Thorax. 2007;62(11):975–80.
Bach JR, Ishikawa Y, Kim H. Prevention of pulmonary morbidity for patients with Duchenne muscular dystrophy. Chest. 1997;112(4):1024–8.
Bach JR. Amyotrophic lateral sclerosis: predictors for prolongation of life by noninvasive respiratory aids. Arch Phys Med Rehabil. 1995;76(9):828–32.
Bach JR, Saporito LR. Criteria for extubation and tracheostomy tube removal for patients with ventilatory failure: a different approach to weaning. Chest. 1996;110(6):1566–71.
Finder JD, Birnkrant D, Carl J, Farber HJ, Gozal D, Iannaccone ST, et al. Respiratory care of the patient with Duchenne muscular dystrophy: ATS consensus statement. Am J Respir Crit Care Med. 2004;170(4):456–65.
Bourke SC, Tomlinson M, Williams TL, Bullock RE, Shaw PJ, Gibson GJ. Effects of non-invasive ventilation on survival and quality of life in patients with amyotrophic lateral sclerosis: a randomised controlled trial. Lancet Neurol. 2006;5(2):140–7.
Annane D, Orlikowski D, Chevret S. Nocturnal mechanical ventilation for chronic hypoventilation in patients with neuromuscular and chest wall disorders. Cochrane Database Syst Rev. 2014;12
Ishikawa Y, Miura T, Ishikawa Y, Aoyagi T, Ogata H, Hamada S, et al. Duchenne muscular dystrophy: survival by cardio-respiratory interventions. Neuromuscul Disord. 2011;21(1):47–51.
Ward S, Chatwin M, Heather S, Simonds AK. Randomised controlled trial of non-invasive ventilation (NIV) for nocturnal hypoventilation in neuromuscular and chest wall disease patients with daytime normocapnia. Thorax. 2005;60(12):1019–24.
Andersen T, Sandnes A, Brekka AK, Hilland M, Clemm H, Fondenes O, et al. Laryngeal response patterns influence the efficacy of mechanical assisted cough in amyotrophic lateral sclerosis. Thorax. 2017;72(3):221–9.
Marchese S, Lo Coco D, Lo Coco A. Outcome and attitudes toward home tracheostomy ventilation of consecutive patients: a 10-year experience. Respir Med. 2008;102(3):430–6.
Bach JR. A comparison of long-term ventilatory support alternatives from the perspective of the patient and care giver. Chest. 1993;104(6):1702–6.
Bach JR, Tran J, Durante S. Cost and physician effort analysis of invasive vs. noninvasive respiratory management of Duchenne muscular dystrophy. Am J Phys Med Rehabil. 2015;94(6):474–82.
Rabkin J, Ogino M, Goetz R, McElhiney M, Marziliano A, Imai T, et al. Tracheostomy with invasive ventilation for ALS patients: neurologists’ roles in the US and Japan. Amyotroph Lateral Scler Frontotemporal Degener. 2013;14(2):116–23.
Birnkrant DJ. The American College of Chest Physicians consensus statement on the respiratory and related management of patients with Duchenne muscular dystrophy undergoing anesthesia or sedation. Pediatrics. 2009;123(Suppl 4):S242–4.
Gupta H, Gupta PK, Fang X, Miller WJ, Cemaj S, Forse RA, et al. Development and validation of a risk calculator predicting postoperative respiratory failure. Chest. 2011;140(5):1207–15.
Arozullah AM, Daley J, Henderson WG, Khuri SF. Multifactorial risk index for predicting postoperative respiratory failure in men after major noncardiac surgery. The National Veterans Administration Surgical Quality Improvement Program. Ann Surg. 2000;232(2):242–53.
Canet J, Gallart L, Gomar C, Paluzie G, Vallès J, Castillo J, et al. ARISCAT Group.Prediction of postoperative pulmonary complications in a population-based surgical cohort. Anesthesiology. 2010;113(6):1338–50.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Orr, J.E., Wolfe, L.F. (2020). Evaluation of the Pulmonary System. In: Weissbrod, P., Francis, D. (eds) Neurologic and Neurodegenerative Diseases of the Larynx. Springer, Cham. https://doi.org/10.1007/978-3-030-28852-5_9
Download citation
DOI: https://doi.org/10.1007/978-3-030-28852-5_9
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-28851-8
Online ISBN: 978-3-030-28852-5
eBook Packages: MedicineMedicine (R0)