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Anxiety Disorders Among Older Adults: Empirically Supported Treatments and Special Considerations

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Clinical Handbook of Anxiety Disorders

Part of the book series: Current Clinical Psychiatry ((CCPSY))

Abstract

This chapter introduces the therapeutic approaches and major clinical themes in the treatment of late-life anxiety. Late-life anxiety disorders are prevalent, disabling, and often undertreated. Furthermore, when treatment is sought, most older adults are not offered empirically supported care, making effective treatment less likely. However, numerous modalities for effective treatment exist, including pharmacologic and non-pharmacologic approaches. Many older adults respond well to monotherapy strategies, while others benefit from augmented or combined approaches to address the needs most relevant to older adults. In this chapter, we review the evidence regarding appropriate psychopharmacologic and psychotherapeutic interventions for treating late-life anxiety disorders. We also address themes common to older adults, including cognitive impairment, age-related socioemotional changes, medical comorbidities, and treatment underutilization, and provide the reader with strategies for managing these complex issues in late-life anxiety.

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References

  1. Gould CE, O’Hara R, Goldstein MK, Beaudreau SA. Multimorbidity is associated with anxiety in older adults in the health and retirement study. Int J Geriatr Psychiatry. 2016;31(10):1105–15.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Tetzner J, Schuth M. Anxiety in late adulthood: associations with gender, education, and physical and cognitive functioning. Psychol Aging. 2016;31(5):532–44.

    Article  PubMed  Google Scholar 

  3. Garrido MM, Kane RL, Kaas M, Kane RA. Use of mental health care by community-dwelling older adults. J Am Geriatr Soc. 2011;59(1):50–6.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Association AP. Diagnostic and statistical manual of mental disorders (DSM-5®). Arlington: American Psychiatric Pub; 2013. 1 p.

    Book  Google Scholar 

  5. Byers AL, Yaffe K, Covinsky KE, Friedman MB, Bruce ML. High occurrence of mood and anxiety disorders among older adults: the National Comorbidity Survey Replication. Arch Gen Psychiatry. 2010;67(5):489–96.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Canuto A, Weber K, Baertschi M, Andreas S, Volkert J, Dehoust MC, et al. Anxiety disorders in old age: psychiatric comorbidities, quality of life, and prevalence according to age, gender, and country. Am J Geriatr Psychiatry. 2018;26(2):174–85.

    Article  PubMed  Google Scholar 

  7. Remes O, Brayne C, van der Linde R, Lafortune L. A systematic review of reviews on the prevalence of anxiety disorders in adult populations. Brain Behav. 2016;6(7):e00497.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Henderson AS, Jorm AF, Korten AE, Jacomb P, Christensen H, Rodgers B. Symptoms of depression and anxiety during adult life: evidence for a decline in prevalence with age. Psychol Med. 1998;28(6):1321–8.

    Article  CAS  PubMed  Google Scholar 

  9. Jeste DV, Blazer DG, First M. Aging-related diagnostic variations: need for diagnostic criteria appropriate for elderly psychiatric patients. Biol Psychiatry. 2005;58(4):265–71.

    Article  PubMed  Google Scholar 

  10. Miloyan B, Byrne GJ, Pachana NA. Age-related changes in generalized anxiety disorder symptoms. Int Psychogeriatr. Cambridge University Press. 2014;26(4):565–72.

    Article  PubMed  Google Scholar 

  11. Richardson TM, Simning A, He H, Conwell Y. Anxiety and its correlates among older adults accessing aging services. Int J Geriatr Psychiatry. 2011;26(1):31–8.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Wolitzky-Taylor KB, Castriotta N, Lenze EJ, Stanley MA, Craske MG. Anxiety disorders in older adults: a comprehensive review. Depress Anxiety. 2010;27(2):190–211.

    Article  PubMed  Google Scholar 

  13. Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry. American Medical Association. 2005;62(6):593–602.

    Article  PubMed  Google Scholar 

  14. Hendriks GJ, Oude Voshaar RC, Keijsers GPJ, Hoogduin CAL, van Balkom AJLM. Cognitive-behavioural therapy for late-life anxiety disorders: a systematic review and meta-analysis. Acta Psychiatr Scand. 2008;117(6):403–11.

    Article  CAS  PubMed  Google Scholar 

  15. Brenes GA, Miller ME, Williamson JD, McCall WV, Knudson M, Stanley MA. A randomized controlled trial of telephone-delivered cognitive-behavioral therapy for late-life anxiety disorders. Am J Geriatr Psychiatry. 2012;20(8):707–16.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Klainin-Yobas P, Oo WN, Suzanne Yew PY, Lau Y. Effects of relaxation interventions on depression and anxiety among older adults: a systematic review. Aging Ment Health. 2015;19(12):1043–55.

    Article  PubMed  Google Scholar 

  17. Burroughs H, Bartlam B, Ray M, Kingstone T, Shepherd T, Ogollah R, et al. A feasibility study for non-traditional providers to support the management of elderly people with anxiety and depression: the NOTEPAD study protocol. Trials. 2018;19(1):172.

    Article  PubMed  PubMed Central  Google Scholar 

  18. Berlin RK, Butler PM, Perloff MD. Gabapentin therapy in psychiatric disorders: a systematic review. Prim Care Companion CNS Disord. 2015;17:5.

    Google Scholar 

  19. Steenen SA, van Wijk AJ, van der Heijden GJMG, van Westrhenen R, de Lange J, de Jongh A. Propranolol for the treatment of anxiety disorders: systematic review and meta-analysis. J Psychopharmacol. (Oxford). 2016;30(2):128–39.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  20. Benítez CIP, Smith K, Vasile RG, Rende R, Edelen MO, Keller MB. Use of benzodiazepines and selective serotonin reuptake inhibitors in middle-aged and older adults with anxiety disorders: a longitudinal and prospective study. Am J Geriatr Psychiatr. 2008;16(1):5–13.

    Article  Google Scholar 

  21. Olfson M, King M, Schoenbaum M. Benzodiazepine use in the United States. JAMA Psychiat. 2015;72(2):136–42.

    Article  Google Scholar 

  22. Palmaro A, Dupouy J, Lapeyre-Mestre M. Benzodiazepines and risk of death: results from two large cohort studies in France and UK. Eur Neuropsychopharmacol. 2015;25(10):1566–77.

    Article  CAS  PubMed  Google Scholar 

  23. Wagner AK, Zhang F, Soumerai SB, Walker AM, Gurwitz JH, Glynn RJ, et al. Benzodiazepine use and hip fractures in the elderly: who is at greatest risk? Arch Intern Med. 2004;164(14):1567–72.

    Article  PubMed  Google Scholar 

  24. Lader M. Benzodiazepines revisited – will we ever learn? Addiction. 2011;106(12):2086–109.

    Article  PubMed  Google Scholar 

  25. Maree RD, Marcum ZA, Saghafi E, Weiner DK, Karp JF. A systematic review of opioid and benzodiazepine misuse in older adults. Am J Geriatr Psychiatry. 2016;24(11):949–63.

    Article  PubMed  PubMed Central  Google Scholar 

  26. By the American Geriatrics Society 2015 Beers Criteria Update Expert Panel. American Geriatrics Society 2015 updated beers criteria for potentially inappropriate medication use in older adults. J Am Geriatr Soc. 2015;63(11):2227–46.

    Article  Google Scholar 

  27. Rosnick CB, Wetherell JL, White KS, Andreescu C, Dixon D, Lenze EJ. Cognitive-behavioral therapy augmentation of SSRI reduces cortisol levels in older adults with generalized anxiety disorder: a randomized clinical trial. J Consult Clin Psychol. 2016;84(4):345–52.

    Article  PubMed  PubMed Central  Google Scholar 

  28. Hendriks GJ, Keijsers GPJ, Kampman M, Oude Voshaar RC, Verbraak MJPM, Broekman TG, et al. A randomized controlled study of paroxetine and cognitive-behavioural therapy for late-life panic disorder. Acta Psychiatr Scand. 2010;122(1):11–9.

    Article  CAS  PubMed  Google Scholar 

  29. Pachana NA, Woodward RM, Byrne GJA. Treatment of specific phobia in older adults. Clin Interv Aging. 2007;2(3):469–76.

    PubMed  PubMed Central  Google Scholar 

  30. Schlossberg NK. Revitalizing retirement. American Psychological Association: Washington, DC: Lifetools; 2009. 1 p.

    Google Scholar 

  31. Kypraiou A, Sarafis P, Tsounis A, Bitsi G, Andreanides E, Constantinidis T, et al. Depression and anxiety in Greek male veterans after retirement. Mil Med. 2017;182(3):e1639–44.

    Article  PubMed  Google Scholar 

  32. Vehling S, Kissane DW. Existential distress in cancer: alleviating suffering from fundamental loss and change. Psychooncology. 2018;27(11):2525–30.

    Article  PubMed  Google Scholar 

  33. Hyland P, Shevlin M, Cloitre M, Karatzias T, Vallières F, McGinty G, et al. Quality not quantity: loneliness subtypes, psychological trauma, and mental health in the US adult population. Soc Psychiatr Epidemiol. 2019;54(9):1089–99.

    Article  PubMed  Google Scholar 

  34. Laidlaw K, Kishita N. Age-appropriate augmented cognitive behavior therapy to enhance treatment outcome for late-life depression and anxiety disorders. GeroPsych. 2015;28(2):57–66.

    Article  Google Scholar 

  35. Yochim B. Neurocognitive disorders in late life. In: Yochim B, Woodhead E, editors. Psychology of aging. New York: Springer Publishing Comapany; 2018. p. 201–22.

    Chapter  Google Scholar 

  36. Yates JA, Clare L, Woods RT. Mild cognitive impairment and mood: a systematic review. Rev Clin Gerontol. 2013;23(04):317–56.

    Article  Google Scholar 

  37. Schultz SK, Moser DJ, Bishop JR, Ellingrod VL. Phobic anxiety in late-life in relationship to cognition and 5HTTLPR polymorphism. Psychiatr Genet. 2005;15(4):305–6.

    Article  PubMed  Google Scholar 

  38. Gulpers B, Ramakers I, Hamel R, Köhler S, Oude Voshaar R, Verhey F. Anxiety as a predictor for cognitive decline and dementia: a systematic review and meta-analysis. Am J Geriatr Psychiatry. 2016;24(10):823–42.

    Article  PubMed  Google Scholar 

  39. Becker E, Orellana Rios CL, Lahmann C, Rücker G, Bauer J, Boeker M. Anxiety as a risk factor of Alzheimer’s disease and vascular dementia. Br J Psychiatry. 2018;213(5):654–60.

    Article  PubMed  Google Scholar 

  40. Gimson A, Schlosser M, Huntley JD, Marchant NL. Support for midlife anxiety diagnosis as an independent risk factor for dementia: a systematic review. BMJ Open. 2018;8(4):e019399.

    Article  PubMed  PubMed Central  Google Scholar 

  41. Mah L, Binns MA, Steffens DC. Alzheimer’s disease neuroimaging initiative. Anxiety symptoms in amnestic mild cognitive impairment are associated with medial temporal atrophy and predict conversion to Alzheimer disease. Am J Geriatr Psychiatry. 2015;23(5):466–76.

    Article  PubMed  Google Scholar 

  42. Kiosses DN, Alexopoulos GS. Problem-solving therapy in the elderly. Curr Treat Options Psychiatry. 2014;1(1):15–26.

    Article  PubMed  PubMed Central  Google Scholar 

  43. Mohlman J, Gorenstein EE, Kleber M, de Jesus M, Gorman JM, Papp LA. Standard and enhanced cognitive-behavior therapy for late-life generalized anxiety disorder: two pilot investigations. Am J Geriatr Psychiatr. 2003;11(1):24–32.

    Google Scholar 

  44. Teri L, Logsdon RG, Uomoto J, McCurry SM. Behavioral treatment of depression in dementia patients: a controlled clinical trial. J Gerontol B Psychol Sci Soc Sci. 1997;52(4):P159–66.

    Article  CAS  PubMed  Google Scholar 

  45. Mast B. Clinical and person-centered perspectives on dementia assessment and care. San Francisco; 2018. p. 1–246.

    Google Scholar 

  46. Cheston R, Ivanecka A. Individual and group psychotherapy with people diagnosed with dementia: a systematic review of the literature. Int J Geriatr Psychiatry. 2016;32(1):3–31.

    Article  PubMed  Google Scholar 

  47. Craig C, Hiskey S, Royan L, Poz R, Spector A. Compassion focused therapy for people with dementia: a feasibility study. Int J Geriatr Psychiatry. 2018;33(12):1727–35.

    Article  PubMed  Google Scholar 

  48. Mittelman MS, Haley WE, Clay OJ, Roth DL. Improving caregiver well-being delays nursing home placement of patients with Alzheimer disease. Neurology. 2006;67(9):1592–9.

    Article  PubMed  Google Scholar 

  49. Smoller JW, Pollack MH, Wassertheil-Smoller S, Jackson RD, Oberman A, Wong ND, et al. Panic attacks and risk of incident cardiovascular events among postmenopausal women in the Women’s Health Initiative observational study. Arch Gen Psychiatry. 2007;64(10):1153–60.

    Article  PubMed  Google Scholar 

  50. Solano JP, Gomes B, Higginson IJ. A comparison of symptom prevalence in far advanced cancer, AIDS, heart disease, chronic obstructive pulmonary disease and renal disease. J Pain Symptom Manag. 2006;31(1):58–69.

    Article  Google Scholar 

  51. Eisner MD, Blanc PD, Yelin EH, Katz PP, Sanchez G, Iribarren C, et al. Influence of anxiety on health outcomes in COPD. Thorax. 2010;65(3):229–34.

    Article  PubMed  Google Scholar 

  52. Todaro JF, Shen B-J, Raffa SD, Tilkemeier PL, Niaura R. Prevalence of anxiety disorders in men and women with established coronary heart disease. J Cardiopulm Rehabil Prev. 2007;27(2):86–91.

    Article  PubMed  Google Scholar 

  53. Hill K, Geist R, Goldstein RS, Lacasse Y. Anxiety and depression in end-stage COPD. Eur Respir J. 2008;31(3):667–77.

    Article  CAS  PubMed  Google Scholar 

  54. Benderly M, Kalter-Leibovici O, Weitzman D, Blieden L, Buber J, Dadashev A, et al. Depression and anxiety are associated with high health care utilization and mortality among adults with congenital heart disease. Int J Cardiol. 2018;276:81–6.

    Article  PubMed  Google Scholar 

  55. Kogan JN, Edelstein BA, McKee DR. Assessment of anxiety in older adults: current status. J Anxiety Disord. 2000;14(2):109–32.

    Article  CAS  PubMed  Google Scholar 

  56. Satterfield JM. Minding the body workbook. Oxford: Oxford University Press; 2008. 1 p.

    Book  Google Scholar 

  57. Alegria M, Alvarez K, Ishikawa RZ, DiMarzio K, McPeck S. Removing obstacles to eliminating racial and ethnic disparities in behavioral health care. Health Aff (Millwood). 2016;35(6):991–9.

    Article  Google Scholar 

  58. Brenes GA, Danhauer SC, Lyles MF, Hogan PE, Miller ME. Barriers to mental health treatment in rural older adults. Am J Geriatr Psychiatry. 2015;23(11):1172–8.

    Article  PubMed  PubMed Central  Google Scholar 

  59. Jimenez DE, Cook B, Bartels SJ, Alegria M. Disparities in mental health service use of racial and ethnic minority elderly adults. J Am Geriatr Soc. 2013;61(1):18–25.

    Article  PubMed  Google Scholar 

  60. Janssen EHC, van de Ven PM, Terluin B, Verhaak PFM, van Marwijk HWJ, Smolders M, et al. Recognition of anxiety disorders by family physicians after rigorous medical record case extraction: results of the Netherlands study of depression and anxiety. Gen Hosp Psychiatry. 2012;34(5):460–7.

    Article  PubMed  Google Scholar 

  61. Perreault M, Lafortune D, Laverdure A, Chartier-Otis M, Bélanger C, Marchand A, et al. Barriers to treatment access reported by people with anxiety disorders. Can J Psychiatr. 2nd ed. 2013;58(5):300–5.

    Article  Google Scholar 

  62. Bishop TF, Press MJ, Keyhani S, Pincus HA. Acceptance of insurance by psychiatrists and the implications for access to mental health care. JAMA Psychiat. 2014;71(2):176–81.

    Article  CAS  Google Scholar 

  63. Berryhill MB, Halli-Tierney A, Culmer N, Williams N, Betancourt A, King M, et al. Videoconferencing psychological therapy and anxiety: a systematic review. Fam Pract. 2018;36:53–63.

    Article  Google Scholar 

  64. van’t Veer-Tazelaar PJ, van HWJ M, van Oppen P, van HPJ H, van der Horst HE, Cuijpers P, et al. Stepped-care prevention of anxiety and depression in late life: a randomized controlled trial. Arch Gen Psychiatry. 2009;66(3):297–304.

    Article  Google Scholar 

  65. United States Census Bureau. Older people projected to outnumber children for first time in U.S. history. 2018.

    Google Scholar 

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Ishikawa, R.Z., Vyas, C., Okereke, O. (2020). Anxiety Disorders Among Older Adults: Empirically Supported Treatments and Special Considerations. In: Bui, E., Charney, M., Baker, A. (eds) Clinical Handbook of Anxiety Disorders. Current Clinical Psychiatry. Humana, Cham. https://doi.org/10.1007/978-3-030-30687-8_9

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  • DOI: https://doi.org/10.1007/978-3-030-30687-8_9

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