Abstract
In the previous chapter, we introduced a semi-quantitative miniaturized “FusBLU” assay. We herein described a new strategy for non-invasive TMPRSS2-ERG detection in patient urinary samples by coupling the isothermal reverse transcription-recombinase polymerization amplification (RT-RPA) to amplify TMPRSS2-ERG transcripts and directly detect the amplicons using surface-enhanced Raman scattering (SERS).
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Koo, K.M. (2019). Label-Free Surface-Enhanced Raman Scattering Detection System for Clinical Biomarker Targets. In: Advancing Gene Fusion Detection Towards Personalized Cancer Nanodiagnostics . Springer Theses. Springer, Cham. https://doi.org/10.1007/978-3-030-31000-4_3
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DOI: https://doi.org/10.1007/978-3-030-31000-4_3
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