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Nanomaterials for Wound Healing

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Nanomaterials for Regenerative Medicine

Part of the book series: Stem Cell Biology and Regenerative Medicine ((STEMCELL))

Abstract

Tissue wounds cause a significant social and economic burden, which results in diminished quality of life and increased patient mortality. In the USA alone, the estimated cost of wound care ranges from $28.1 to $96.8 billion. The rapid rise of an aging population with chronic debilitating diseases, including obesity and diabetes, contributes to the unmet critical need for better therapeutics for impaired wound healing in patients. Conventional wound management fails to provide rapid tissue repair and restoration of function, particularly in these diseased states. Wound healing is a tightly orchestrated, complex, and dynamic physiological process occurring in a tightly controlled manner that requires more advanced alternative therapeutic approaches. An understanding of the basic biological mechanisms in wound repair underpins the development of novel therapeutic approaches for restoration of tissue function. The use of nanomaterials in wound management represents a unique tool that can be specifically designed to closely reflect the underlying physiological processes in damaged tissues. Harnessing this technology results in a cost-effective and individualized approach to wound management, which has the potential to revolutionize wound management. This chapter presents a basic overview of the pathophysiology of wound healing and an approach to utilizing nanomaterials for wound healing therapy.

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  1. Department of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, IN, USA

    Gozde Uzunalli

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    Ayse Begum Tekinay

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Uzunalli, G. (2019). Nanomaterials for Wound Healing. In: Tekinay, A. (eds) Nanomaterials for Regenerative Medicine. Stem Cell Biology and Regenerative Medicine. Humana, Cham. https://doi.org/10.1007/978-3-030-31202-2_3

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