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Oral Immunotherapy (OIT)

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Pediatric Food Allergy

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Abstract

Currently, there is no approved therapy for food allergies. Thus, treatment strategies are limited to avoidance of the allergic food and having emergency treatment available for reactions. An increasing amount of research into food allergy treatments has occurred in response to this void, with oral immunotherapy (OIT) being the most researched treatment strategy to date. From the multiple studies examining OIT for IgE-mediated food allergies, it appears that this treatment can lead to desensitization in the majority of patients who tolerate the therapy. Adverse effects to OIT are common and sometimes severe. Therefore, combination with other therapeutic approaches may be needed to improve the safety of OIT for many patients.

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Authors and Affiliations

  1. Department of Pediatrics, The University of Tennessee Health Science Center and LeBonheur Children’s Hospital, Memphis, TN, USA

    Jay A. Lieberman

  2. Department of Pediatrics, Division of Allergy and Immunology, Jaffe Food Allergy Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA

    Julie Wang

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Correspondence to Julie Wang .

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  1. Center for Food Allergy and Asthma Research, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

    Ruchi S. Gupta

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Lieberman, J.A., Wang, J. (2020). Oral Immunotherapy (OIT). In: Gupta, R. (eds) Pediatric Food Allergy . Springer, Cham. https://doi.org/10.1007/978-3-030-33292-1_17

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