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Effects of Na+ and Ca++ on the Spontaneous Excitation of the Bivalve Heart Muscle

  • Chapter
Comparative Physiology of the Heart: Current Trends

Part of the book series: Experientia Supplementum ((EXS))

Abstract

If one were to attempt a study of the invertebrate heart muscle, the preparation which would immediately come to mind would be the classical clam heart preparation. Almost 30 years ago Prosser 1* discovered that the venus heart was extremely sensitive to acetylcholine. Subsequently Welsh 2,3 used the heart of the Venus mercenaria as a tool for the bioassay of acetylcholine and its analogs and also for the study of the pharmacology and mechanisms of cardio-regulation. Recently Greenberg 4 examined more than 40 different bivalve hearts for their response to acetylcholine. Many of the physiological studies on these muscles have been summarized by Krijgsman and Divaris 5 and more recently by Hill and Welsh 6.

This work was aided by a research grant from the Ministry of Education of Japan.

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Author information

Authors and Affiliations

  1. Department of Physiology, School of Medicine, Hiroshima University, Hiroshima, Japan

    H. Irisawa, A. Irisawa & N. Shigeto

Authors
  1. H. Irisawa
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  2. A. Irisawa
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  3. N. Shigeto
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Editor information

Editors and Affiliations

  1. Dartmouth Medical School, Hanover, New Hampshire, USA

    F. V. McCann

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© 1969 Springer Basel AG

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Irisawa, H., Irisawa, A., Shigeto, N. (1969). Effects of Na+ and Ca++ on the Spontaneous Excitation of the Bivalve Heart Muscle. In: McCann, F.V. (eds) Comparative Physiology of the Heart: Current Trends. Experientia Supplementum. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-6800-6_15

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  • DOI: https://doi.org/10.1007/978-3-0348-6800-6_15

  • Publisher Name: Birkhäuser, Basel

  • Print ISBN: 978-3-0348-6788-7

  • Online ISBN: 978-3-0348-6800-6

  • eBook Packages: Springer Book Archive

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