Skip to main content
SpringerLink
Log in

The β-Adrenergic Blocking Agents Pharmacology and Structure-Activity Relationships

  • Chapter
Fortschritte der Arzneimittelforschung / Progress in Drug Research / Progrès des recherches pharmaceutiques

  • 72 Accesses

Abstract

Outside chemical interference with the sympathetic nervous system through the administration of drugs has resulted in major advances in the therapy of respiratory, cardiovascular, and mental diseases. Agents capable of blocking or enhancing the action of epinephrine and norepinephrine, regulating their biosynthesis or metabolism, influencing their uptake or release from storage sites became valuable tools in the study of the etiology of many pathologic processes and in the elucidation of the various functions of these neurohormones.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. J. N. Langley, J. Physiol. (Lond.) 1, 339 (1878).

    Google Scholar 

  2. J. N. Langley, J. Physiol. (Lond.) 33, 374 (1905).

    Google Scholar 

  3. N. C. Moran, Cellular Basis of the Cardiac Action of Drugs, Proceedings of Symposium Held in Philadelphia, February (University of Pennsylvania Press 1964), in press.

    Google Scholar 

  4. E. J. Ariens, A. M. Simonis, and J. M. van Rossum, Molecular Pharmacology, vol. I (ed. E. J. Ariens, Academic Press, New York and London 1964 ), p. 287.

    Google Scholar 

  5. R. P. Stephenson, Brit. J. Pharmacol. 11, 379 (1956).

    Google Scholar 

  6. H. H. Dale, J. Physiol. 34, 163 (1906).

    Google Scholar 

  7. R. P. Ahlquist, Am. J. Physiol. 153, 586 (1948).

    Google Scholar 

  8. R. P. Ahlquist and B. Levy, J. Pharmacol, exp. Therap. 127, 146 (1959).

    Google Scholar 

  9. B. Levy, J. Pharmacol, exp. Therap. 127, 150 (1959).

    Google Scholar 

  10. R. P. Ahlquist, Pharmacology in Medicine, 2nd Edition (ed. A. Drill, McGraw-Hill Book Company, Inc. 1958 ), p. 378.

    Google Scholar 

  11. G. K. Moe, S. D. alton, B. R. ennick, and W. A. reyburger, J. Pharmacol, exp. Therap. 94, 319 (1948).

    Google Scholar 

  12. N. C. Moran, J. I. oore, A. K. olcomb and G. ushat, J. Phramacol. exp. Therap. 136, 327 (1962).

    Google Scholar 

  13. R. L. Katz, Anesthesiology 26, 289 (1965).

    Article  Google Scholar 

  14. G. Fawaz, Brit. J. Pharmacol. 6, 492 (1951).

    Google Scholar 

  15. P. Somani and B. K. B. um, J. Pharmacol, exp. Therap., in press.

    Google Scholar 

  16. G. H. Acheson, A. arah, and G. N. rench, J. Pharmacol, exp. Therap. 97, 455 (1949).

    Google Scholar 

  17. L. Szekeres and E. M. aughan-illiams, J. Physiol. (Lond.), 160, 470 (1962).

    Google Scholar 

  18. J. L. Gilbert, G. Lange, and C. McBrooks, Circulation Res. I, 417 (1959).

    Google Scholar 

  19. P. E. Dresel, Can. J. Biochem. Physiol. 38, 375 (1960).

    Article  Google Scholar 

  20. J. I. Moore and H. H. wain, J. Pharmacol, exp. Therap. 128, 243 (1960).

    Google Scholar 

  21. L. G. Schull, G. erry, and R. allarreal, Anesthesiology 22, 444 (1960).

    Article  Google Scholar 

  22. W. J. Murray, R. L. night, and D. A. avis, Proc. Soc. exp. Biol. [N.Y.] 113, 439 (1963).

    Google Scholar 

  23. P. Somani and B. K. B. um, J. Pharmacol, exp. Therap. 147, 194 (1965).

    Google Scholar 

  24. P. Somani, J. G. Fleming, G. K. Chan, and B. K. B. Lum, J.Pharmacol, exp. Therap., 151, 32 (1966).

    Google Scholar 

  25. B. R. Lucchesi and H. F. ardman, J. Pharmacol, exp. Therap. 132, 372 (1961).

    Google Scholar 

  26. A. Sekiya and E. M. aughan-illiams, Brit. J. Pharmacol. 21, 462 (1963).

    Google Scholar 

  27. B. R. Lucchesi, J. Pharmacol, exp. Therap. 145, 286 (1964).

    Google Scholar 

  28. E. W. Gill and E. M. aughan-illiams, Nature 201, 199 (1964).

    Article  Google Scholar 

  29. J. H. Hagen and P. B. agen, Actions of Hormones on Molecular Processes (eds. G. Litwack and D. Kretchevsky, John Wiley & Sons, Inc. 1964 ), p. 92.

    Google Scholar 

  30. S. Mayer, N. C. oran, and J. ain, J. Pharmacol, exp. Therap. 134, 18 (1961).

    Google Scholar 

  31. J. J. Burns, K. I. olville, L. A. indsay, and R. A. alvador, J. Pharmacol, exp. Therap. 144, 163 (1964).

    Google Scholar 

  32. R. A. Salvador, K. I. olville, S. A. pril, and J. J. urns, J.Pharmacol, exp. Therap. 144, 173 (1964).

    Google Scholar 

  33. H. M. Maling, M. A.illiams, B. ighman, J. arbus, and J. unter, Arch. exp. Path. Pharmak. 248, 54 (1964).

    Google Scholar 

  34. W. W. Fleming and D. F. awkins, J. Pharmacol, exp. Therap. 129, 1 (1960).

    Google Scholar 

  35. E. E. Vogin and N. S. halla, J. Pharmacol, exp. Therap. 147, 65 (1965).

    Google Scholar 

  36. R. F. Furchtgott, Pharmacol. Rev. 11, 429 (1959).

    Google Scholar 

  37. D. E. Donald, J. A. vale, and J. T. T. hephard, J. Pharmacol, exp. Therap., 143, 344 (1964).

    Google Scholar 

  38. N. C. Moran, private communication.

    Google Scholar 

  39. C. M. Maxwell, E. obertson, and R. B. lliott, Austral. J. exp. Biol. 41, 511 (1963).

    Article  Google Scholar 

  40. E. E. Vogin and A. J. ice, Archs int. Pharmacodyn. Thér. 155, 317 (1965).

    Google Scholar 

  41. K. Turker, B. K. iran, and S. aymakcalan, Archs int. Pharmacodyn. Thér. 156, 130 (1965).

    Google Scholar 

  42. S. M. Karim, Brit. J. Pharmacol. 24, 365 (1965).

    Google Scholar 

  43. L. S. Goodman, The Pharmacological Basis of Therapeutics ( The MacMillan Company, New York 1955 ), p. 531.

    Google Scholar 

  44. J. Nakano and T. usakari, Proc. Soc. exp. Biol. Med. 119, 350 (1965).

    Google Scholar 

  45. E. J. Ariens and A. M. imonis, Archs int. Pharmacodyn. Thér. 127, 479 (1960).

    Google Scholar 

  46. W. W. Fleming and D. F. awkins, Fed. Proc. 18, 389 (1959).

    Google Scholar 

  47. J. M. Van ossum and M. ujic, Archs int. Pharmacodyn. Thér. 155, 418 (1965).

    Google Scholar 

  48. N. C. Moran, 2nd Catecholamine Symposium, Milan, Italy 1965, in press, Pharmacol. Rev. 18 (1966).

    Google Scholar 

  49. M. Nagasaka, J. ouckaert, A. F. eschaepdryver, and C. eymans, Archs int. Pharmacodyn. Thér. 149, 237 (1964).

    Google Scholar 

  50. E. J. Ariens, A. M. imonis, and J.M. an ossum, Molecular Pharmacology, vol. I (ed. E. J. Ariens, Academic Press, New York), p. 215.

    Google Scholar 

  51. B. Belleau, Adrenergic Mechanisms, CIBA Foundation Symposium (ed. J. R. Vane, Little Brown & Co., Boston 1960 ).

    Google Scholar 

  52. B. Levy and R. P. hlquist, J. Pharmacol, exp. Therap. 130, 334 (1960).

    Google Scholar 

  53. E. J. Ariens, A.M. imonis, and J.M. an ossum, Molecular Pharmacology, vol. I (Academic Press, New York and London, ed. E. J. Ariens 1964 ), p. 253.

    Google Scholar 

  54. A. M. Lands, J. Pharmacol, exp. Therap. 96, 279 (1949).

    Google Scholar 

  55. A. M. Lands, Pharmacol. Rev. 1, 279 (1949).

    Google Scholar 

  56. E. E. Swanson, C. C. cott, M. M. ee, and K. K. hen, J. Pharmacol, exp. Therap. 79, 329 (1943).

    Google Scholar 

  57. A. M. Lands and F. P. uduena, J. Pharmacol, exp. Therap. 117, 331 (1956).

    Google Scholar 

  58. F. P. Luduena, L. von uler, B. F. ullar, and A. M. ands, Archs int. Pharmacodyn. Thér. 111, 392 (1957).

    Google Scholar 

  59. F. P. Luduena, Archs int. Pharmacodyn, Thér. 137, 155 (1962).

    Google Scholar 

  60. A. Kaelin, Helv. Chim. Acta 30, 2132 (1947).

    Article  Google Scholar 

  61. B. Belleau, Proc. 1st Intern. Congr. Pharmacol., Stockholm 1961, 7, 75 (1963).

    Google Scholar 

  62. B. M. Bloom and G. aubach, Ann. Rev. Pharmacol. 2, 67 (1962).

    Article  Google Scholar 

  63. H. Konzett, Arch. exp. Path. Pharmak. 197, 27 (1960).

    Google Scholar 

  64. J. H. Biel, E. chwarz, E. P. prengeler, H. eiser, and H. F. riedman, J. Am. Chem. Soc. 76, 3149 (1954).

    Article  Google Scholar 

  65. T. W. Rall and E. W. utherland, Pharmacol. Rev. 11, 464 (1959).

    Google Scholar 

  66. B. Belleau, Adrenergic Mechanisms, CIBA Foundation Symposium (ed. J. R. Vane, Little Brown & Co., Boston 1960 ), p. 238.

    Google Scholar 

  67. C. E. Powell and I. H. later, J. Pharmacol, exp. Therap. 122, 480 (1958).

    Google Scholar 

  68. N. C. Moran and M. E. erkins, J. Pharmacol, exp. Therap. 124, 223 (1958).

    Google Scholar 

  69. W. E. Glover, A. D. M. reenfield, and R. G. hanks, Brit. J. Pharmacol. 19, 235 (1962).

    Google Scholar 

  70. B. Levy and R. P. hlquist, J. Pharmacol, exp. Therap. 133, 202 (1961).

    Google Scholar 

  71. H. I. El S. li, A. ntonio, and N. augaard, J. Pharmacol, exp. Therap. 142 (1964).

    Article  Google Scholar 

  72. B. J. arge, Brit. J. Pharmacol. 24, 194 (1965).

    Google Scholar 

  73. B. Belleau, J. Med. Chem. 7, 776 (1964).

    Article  Google Scholar 

  74. A. F. Crowther, in press.

    Google Scholar 

  75. C. E. Powell, W. R. ibson, and E. E. wanson, J. Am. Pharmaceut. Assoc. 45, 785 (1956).

    Article  Google Scholar 

  76. R. T. Wong and R. E. hipley, J. New Drugs 3, 172 (1963).

    Google Scholar 

  77. H. Corrodi, H. Persson, A. arlsson, and J. oberts, J. Med. Chem. 6, 751 (1963).

    Article  Google Scholar 

  78. A. F. Crowther, in press.

    Google Scholar 

  79. B. evy, J. Pharmacol, exp. Therap. 146, 129 (1964).

    Google Scholar 

  80. W. D. Meester, H. F. Hardman, and J.J. Barboriak, J. Pharmacol, exp. Therap., in press.

    Google Scholar 

  81. J. J. Burns and L. emburger, Fed. Proc. 24, 298 (1965).

    Google Scholar 

  82. C. H. Ellis, Archs. int. Pharmacodyn. Thér. 150, 144 (1964).

    Google Scholar 

  83. U. M. Teotino, L. olofriz, G. teis, and D. ella ella, J. Pharmacol. London 15, 26 (1963).

    Google Scholar 

  84. A. A. Larsen and P. M. ish, Nature 203, 1283 (1964).

    Article  Google Scholar 

  85. H. C. Stanton, T. irchgessner, and K. armenter, J. Pharmacol, exp. Therap. 149, 174 (1965).

    Google Scholar 

  86. L. E. Folle and D. M. viado, J. Pharmacol, exp. Therap. 149, 79 (1965).

    Google Scholar 

  87. P. M. Lish, J. H. eikel, and K. W. ungan, J. Pharmacol, exp. Therap. 149, 161 (1965).

    Google Scholar 

  88. J. W. Black and J. S. tephenson, Lancet II, 311 (1962).

    Article  Google Scholar 

  89. M. A. Chiong, P. F. innion, and J. D. atcher, Can. J. Physiol. Pharmacol. 43, 411 (1965).

    Article  Google Scholar 

  90. M. Nagasaka, A. F. eschaepdryver, and C. eymans, Archs int. Pharmacodyn. Thér. 149, 232 (1964).

    Google Scholar 

  91. S. Vanov, J. Pharm. Pharmacol. 15, 723 (1963).

    Article  Google Scholar 

  92. J. W. Black, A. F. rowther, R. G. hanks, L. H. mith and A. C. ornhorst, Lancet I, 1080 (1964).

    Article  Google Scholar 

  93. J. Nakano and T. Kusakari, Proc. Soc. exp. Biol. Med. 119, 350 (1965).

    Google Scholar 

  94. H. Haas and G. artfelder, Arzneimittel-Forsch. 12, 549 (1962).

    Google Scholar 

  95. H. Haas, Arzneimittel-Forsch. 14, 461 (1964).

    Google Scholar 

  96. K. I. Melville, H. E. hister, and S. ug, Can. Med. Assoc. J. 90, 761 (1964).

    Google Scholar 

  97. H. Haas, Deutsche Med. Wochenschr. 89, 2117 (1964).

    Article  Google Scholar 

  98. E. W. Sutherland, Recent Progr. in Hormone Res. 5, 441 (1950).

    Google Scholar 

  99. E. W. Sutherland and C. F. ori, J. biol. Chem. 188, 531 (1951).

    Google Scholar 

  100. E. W. Sutherland, Phosphorus Metabolism 1, 53 (1951).

    Google Scholar 

  101. C. F. Cori, Enzymes, Units of Biological Structure and Function (ed. O. H. Gaebler, Academic Press, New York 1956 ), p. 573.

    Google Scholar 

  102. C. F. Cori, Currents in Biochemical Research (ed. D. E. Green, Interscience, New York 1956 ), p. 198.

    Google Scholar 

  103. G. T. Cori and B. llingsworth, Biochem. Biophys. Acta 21, 105 (1956).

    Article  Google Scholar 

  104. T. W. Rall and E. W. utherland, J. biol. Chem. 232, 1065 (1958).

    Google Scholar 

  105. T. W. Rall and E. W. utherland, J. biol. Chem. 232, 1077 (1958).

    Google Scholar 

  106. E. W. Sutherland and T. W. all, Pharmacol. Rev. 12, 265 (1960).

    Google Scholar 

  107. J. Ashmore, J. E. reston, and W. C. ove, Proc. Soc. exp. Biol. Med. 109, 291 (1962).

    Google Scholar 

  108. R. S. McCutcheon, J. Pharmacol, exp. Therap. 136, 209 (1962).

    Google Scholar 

  109. D. C. Kvam, D. A. iggilo, and P. M. ish, J. Pharmacol, exp. Therap. 149, 183 (1965).

    Google Scholar 

  110. T. R. E. Pilkington, R. D. owe, B. F. obinson, and E. itterington, Lancet II, 316 (1962).

    Article  Google Scholar 

  111. V. Claassen and E. L. oach, Archs. int. Pharmacodyn. Thér. 126, 332 (1960).

    Google Scholar 

  112. J. E. Mayer and N. C. oran, J. Pharmacol, exp. Therap. 129, 271 (1960).

    Google Scholar 

  113. K. R. Hornbrook and T. M. rody, J. Pharmacol, exp. Therap. 140, 295 (1963).

    Google Scholar 

  114. F. Murad, Y. M. hi, T. W. all, and E. W. utherland, J. biol. Chem. 237, 1233 (1962).

    Google Scholar 

  115. N. Haugaard and M. E. ess, Pharmacol. Rev. 17, 27 (1965).

    Google Scholar 

  116. S. E. Mayer, M. Dev. Cotten, and N. C. Moran, J. Pharmacol, exp. Therap. 139, 275 (1963).

    Google Scholar 

  117. G. A. Robison, R. W. utcher, I. Oye. H. E. Morgan, and E. W. Sutherland, Molec. Pharmacol. 1, 168 (1965).

    Google Scholar 

  118. R. S. Gordon and A. herkes, J. clin. Invest. 35, 206 (1956).

    Article  Google Scholar 

  119. H. M. Goodman and E. nobil, Proc. Soc. exp. Biol. Med. 102, 493 (1959).

    Google Scholar 

  120. R. J. Havel and A. oldfien, J. Lipid Res. 1, 102 (1959).

    Google Scholar 

  121. E. Wertheimer, M. amosh, and E. hafrir, Am. J. clin. Nutr. 8, 705 (1960).

    Google Scholar 

  122. D. T. Armstrong, R. teele, N. ltzuler, A. unn, J. S. ishop, and R. C. de odo, Am. J. Physiol. 201, 9 (1961).

    Google Scholar 

  123. W. C. Love, L. arr, and J. shmore, J. Pharmacol, exp, Therap. 140, 287 (1963).

    Google Scholar 

  124. S. Fröberg and L. rö, Acta Med. Scand. 174, 635 (1963).

    Article  Google Scholar 

  125. G. G. Muir, D. A. hamberlain, and D. T. edoe, Lancet II, 930 (1964).

    Article  Google Scholar 

  126. R. R. Tuttle and I. R. nnes, The Pharmacologist 6, 165 (1964).

    Google Scholar 

  127. E. W. Gill and E. M. aughan-illiams, Nature 201, 199 (1964).

    Article  Google Scholar 

  128. P. Somani, Doctoral Thesis, Marquette University, 1965.

    Google Scholar 

  129. R. Howe, Biochem. Pharmacol. 12 (suppl.), 85 (1963).

    Article  Google Scholar 

  130. B. R. Lucchesi, J. Pharmacol, exp. Therap. 148, 94 (1965).

    Google Scholar 

  131. A. Sekiya and E. M. aughan-illiams, Brit. J. Pharmacol. 24, 307 (1965).

    Google Scholar 

  132. A. Morales-guilerä and E. M. aughan-illiams, Brit. J. Pharmacol. 24, 319 (1965).

    Google Scholar 

  133. K. Turker and B. iran, Archs int. Pharmacodyn. Thér. 155, 356 (1965).

    Google Scholar 

  134. A. C. Dornhorst and B. F. obinson, Lancet II, 314 (1962).

    Article  Google Scholar 

  135. A. J. Barnett and M. E. randstater, Med. J. Austr. 1, 714 (1964).

    Google Scholar 

  136. P. Keelan, Brit. med. J. 1, 897 (1965).

    Article  Google Scholar 

  137. J. Hamer, T. randjean, L. elendez, and G. E. owton, Brit. med. J. 2, 720 (1964).

    Article  Google Scholar 

  138. D. A. Chamberlain and J. oward, Brit. Heart J. 26, 213 (1964).

    Article  Google Scholar 

  139. B. N. C. Prichard, Brit. med. J. 1, 1227 (1964).

    Article  Google Scholar 

  140. B. N. C. Prichard and P. M. S. illam, Brit. med. J. 2, 725 (1964).

    Article  Google Scholar 

  141. D. C. Harrison, J. R. riffin, and T. J. iene, New Eng. J.Med. 273, 410 (1965).

    Article  Google Scholar 

  142. G. A. O. Alleyne, C. J. ickinson, A. C. ornhorst, R. M. ulton, K. G. reen, I. S. ill, P. urst, D. R. aurence, T. ilkington, B. N. C. richard, B. obinson, and M. L. osenheim, Brit. med. J. 2, 1226 (1963).

    Article  Google Scholar 

  143. G. H. Apthorp, D. A. hamberlain, and G. W. ayward, Brit. Heart J. 26, 218 (1964).

    Article  Google Scholar 

  144. P. M. S. Gillam and B. N. C. richard, Brit. med. J. 2, 337 (1965).

    Article  Google Scholar 

  145. J. P. P. Stock and N. ale, Brit. med. J. 2, 1230 (1963).

    Article  Google Scholar 

  146. D. J. Rowlands, G. owitt, and P. arkman, Brit. med. J. 1, 891 (1965).

    Article  Google Scholar 

  147. R. R. Taylor, C. I. Johnstone, and A. D. Jose, New Engl. J. Med. 271, 877 (1964).

    Google Scholar 

  148. J. Hellewell and M. W. otts, Anaesthesia 20, 269 (1965).

    Article  Google Scholar 

  149. M. Johnstone, Brit. J. Anesthesia 36, 224 (1964).

    Article  Google Scholar 

  150. J. P. Payne and R. M. enfield, Brit. med. J. 1, 603 (1964).

    Article  Google Scholar 

  151. A. C. Dornhorst and D. R. aurence, Brit. med. J. 2, 1250 (1963).

    Article  Google Scholar 

  152. S. de Blasi, Proc. 3rd World Congr. Anaesthesiology, Saõ Paulo, Brazil, vol. 1, 128 (1964).

    Google Scholar 

  153. A. I. G. Robertson, Postgrad, med. J. 41, 481 (1965).

    Article  Google Scholar 

  154. E. M. M. Besterman and D. H. riedlander, Postgrad, med. J. 41, 526 (1965)

    Article  Google Scholar 

  155. T. C. Tsolakas, J. P. H. avies, and S. ram, Lancet II, 1064 (1964).

    Article  Google Scholar 

  156. R. S. McNeill, Lancet II, 1101 (1964).

    Google Scholar 

  157. G. E. Paget, Brit. med. J. 2, 1266 (1963).

    Article  Google Scholar 

  158. A. C. Dornhorst, Second Catecholamine Symposium, Milan, Italy, July 1965, in press, Pharmacologic Reviews (1965).

    Google Scholar 

  159. D. A. Chamberlain, unpublished report.

    Google Scholar 

  160. B. Strassle and D. urckhardt, Schweiz, med. Wschr. 95, 667 (1965).

    Google Scholar 

  161. J. C. Didisheim and R. ebersax, Med. et Hygiene 22, 863 (1964).

    Google Scholar 

  162. B. Tschirdewahn and H. lepzig, Deutsche Med. Wschr. 88, 1702 (1964).

    Article  Google Scholar 

  163. G. Knoch, M. chlepper, and E. itzleb, Med. Klin. 58, 1485 (1963).

    Google Scholar 

  164. P. Hoffmann, Med. Klin. 28, 1387 (1964).

    Google Scholar 

  165. B. Bloom, Symposium in Medicinal Chemistry, London 1965, in press, Pharmacological Reviews (ed. G. H. Acheson, The Williams and Wilkins, Co., Baltimore, Maryland).

    Google Scholar 

  166. M. Nickerson, Proc. 2nd International Pharmacological Meeting, vol. 3 (ed. G. B. Koelle, W. W. Douglas, and A. Carlsson, Pergamon Press, Ltd., Oxford 1965 ), p. 303.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Aldrich Chemical Company, Milwaukee, Wis., USA

    J. H. Biel

  2. Department of Pharmacology, Marquette University School of Medicine, Milwaukee, Wis., USA

    B. K. B. Lum

Authors
  1. J. H. Biel
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. B. K. B. Lum
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Pharmazeutisch-chemische Forschungslaboratorien, Sandoz AG, Basel, Switzerland

    Ernst Jucker

Rights and permissions

Reprints and permissions

Copyright information

© 1966 Birkhäuser Verlag Basel

About this chapter

Cite this chapter

Biel, J.H., Lum, B.K.B. (1966). The β-Adrenergic Blocking Agents Pharmacology and Structure-Activity Relationships. In: Jucker, E. (eds) Fortschritte der Arzneimittelforschung / Progress in Drug Research / Progrès des recherches pharmaceutiques. Fortschritte der Arzneimittelforschung / Progress in Drug Research / Progrès des recherches pharmaceutiques, vol 10. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7059-7_3

Download citation

  • DOI: https://doi.org/10.1007/978-3-0348-7059-7_3

  • Publisher Name: Birkhäuser Basel

  • Print ISBN: 978-3-0348-7061-0

  • Online ISBN: 978-3-0348-7059-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation