Abstract
Since rapid sequencing of bacterial genomes is currently feasible, it has been suggested that sequences for entire genomes of complex organisms will be commonplace in the future. We do not anticipate this happening within the near future, although the technology advances rapidly: A systematics thesis from the late 1980s would commonly be based on 5,000 base pairs of sequence, a thesis of a student of the early 1990s was commonly based on about 50,000 bases of sequence and students currently doing systematics PhDs are commonly basing their theses on 500,000 base pairs of data. Comparative genomics with just ten higher eukaryotic taxa might require a thesis to hold over 50,000,000,000 bases of sequence if entire genomes are utilized. This jump in information content would require the technology to implement a 10,000-fold increase in efficiency.
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Phillips, A.J. (2002). Comparative Phylogenomics: A Strategy for High-throughput Large-scale Sub-genomic Sequencing Projects for Phylogenetic Analysis. In: DeSalle, R., Giribet, G., Wheeler, W. (eds) Techniques in Molecular Systematics and Evolution. Methods and Tools in Biosciences and Medicine. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-8125-8_8
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DOI: https://doi.org/10.1007/978-3-0348-8125-8_8
Publisher Name: Birkhäuser, Basel
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