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Chemotherapy for systemic mycoses

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Progress in Drug Research

Part of the book series: Progress in Drug Research ((PDR,volume 33))

Abstract

The treatment of the systemic mycoses began with the discovery of amphotericin B in 1953 [1]. Thereafter, the pace of discovery of additional antifungal agents has, in comparison with other antiinfectives, been slow, indeed: flucytosine in 1957 [2]; azole derivatives in the 1960s [3], with new triazole derivatives [4, 5] presently under clinical evaluation; polypeptides first reported in 1977 [6] and 1980 [7], with a semisynthetic lipopeptide [8] now nearing clinical trial; allylamines in 1978 [9], with a perorally administrable derivative under clinical study [10].

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  1. Section of Medical Mycology, Department of Internal Medicine, School of Medicine, University of California, 95616, Davis, CA, USA

    Paul D. Hoeprich

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Hoeprich, P.D. (1989). Chemotherapy for systemic mycoses. In: Jucker, E. (eds) Progress in Drug Research. Progress in Drug Research, vol 33. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-9146-2_10

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