Abstract
Understanding complex biological systems, e.g. the cell cycle, requires not only sophisticated experimental techniques but also adequate mathematical models. Many different mathematical approaches, from quantitive to qualitative, from continuous to discrete, have been applied to study the cell in different environmental conditions. In this chapter, we introduce a second complementary modelling approach to study the response of the cell cycle to osmotic and alpha-factor signal: we construct a Boolean network which describes the dynamical behaviour of the cell cycle response to multiple extracellular signals.
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Notes
- 1.
The Hamming distance between two strings of equal length is the number of positions at which the corresponding symbols are different.
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Radmaneshfar, E. (2014). Boolean Model of the Cell Cycle Response to Stress. In: Mathematical Modelling of the Cell Cycle Stress Response. Springer Theses. Springer, Cham. https://doi.org/10.1007/978-3-319-00744-1_4
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DOI: https://doi.org/10.1007/978-3-319-00744-1_4
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