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Neuroimaging Classification of Traumatic Brain Injury

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Neuroimaging of Traumatic Brain Injury

Abstract

In Chapter 3 we discuss the results of correlation study between severity, location, and level of hemispheric and brain stem damage based on clinical, CT, and MRI comparison analysis. CT and MRI data were compared to determine sensitivity and possibilities in detecting brain lesion location and severity based on the mechanisms of injury, trauma severity, and outcome. MRI data were used for a more differentiated evaluation of hemispheric and brain stem damages.

Today it is still unclear what localizations and severity of traumatic brain injury may cause disorders of consciousness and development of coma with variable depth and duration. It equally applies not only to the brain stem but also to the thalamus, basal ganglia, corpus callosum, and cortical-subcortical structures.

To answer this question 162 patients with acute and subacute TBI of various severity were examined by different sequences of magnetic resonance imaging. A comprehensive MRI classification of localization of the brain stem and hemispheric damages has been proposed. This classification significantly correlates with Glasgow Coma Scale and Glasgow Outcome Scale, thus proving its prognostic value. The classification developed for the brain injury localization and levels based on MRI data may become a useful tool for forming the data bank on traumatic brain injury and studying clinical comparative evaluations of efficacy of various approaches for the management of patients with severe TBI.

This chapter has been contributed in collaboration with Eugenia Alexandrova and Gleb Danilov

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References

  • Alexandrova E, Zaitsev O, Tenedieva V, Potapov A, Zakharova N et al (2011) Plasma catecholamines in consciousness recovery in patients with severe traumatic brain injury. Zh Neurol Psikhiatr im SSKorsakova 3:58–63

    Google Scholar 

  • Augustenborg CC (2010) Endogenous feedback network: a new approach to the comprehensive study of consciousness. Conscious cognit 19:547–579

    Article  Google Scholar 

  • Bazarian J, Zhong J, Blyth B et al (2007) Diffusion tensor imaging detects clinically important axonal damage after mild traumatic brain injury: a pilot study. J Neurotrauma 24:1447–1459

    Article  PubMed  Google Scholar 

  • Bragina N, Potapov A, Zaitsev O, Zakharova N et al (2011) Predominant brain lesion level. In: Zaitsev O (ed) Psychopathology of severe head injury. MEDpressinform, Moscow, pp 226–236

    Google Scholar 

  • Castaigne P et al (1981) Paramedian thalamic and midbrain infarcts: clinical and neuropathological study. Ann Neurol 10:127–148

    Article  CAS  PubMed  Google Scholar 

  • Firsching R, Woischneck D, Klein S et al (2001) Classification of severe head injury based on magnetic resonance imaging. Acta Neurochir 143:263–271

    Article  CAS  PubMed  Google Scholar 

  • Gennarelli T, Thibault L, Adams J et al (1982) Diffuse axonal injury and traumatic coma in the primate. Ann Neurol 12:564–574

    Article  CAS  PubMed  Google Scholar 

  • Haacke E, Duhaime A, Gean A et al (2010) Common data elements in radiologic imaging of traumatic brain injury. J Magn Reson Imaging 32(3):516–543

    Article  PubMed  Google Scholar 

  • Hilario A, Ramos A, Millan JM et al (2012) Severe traumatic head injury: prognostic value of brain stem injuries detected at MRI. AJNR Am J Neuroradiol 33:1925–1931

    Article  CAS  PubMed  Google Scholar 

  • Kornienko V, Pronin I (eds) (2009) Diagnostic neuroradiology. Springer, Berlin/Heidelberg

    Google Scholar 

  • Lagares A, Ramos A, Derez-Nunes A et al (2009) The role of MRI in assessing prognosis after severe and moderate head injury. Acta Neurochir 151:341–356

    Article  PubMed  Google Scholar 

  • Lammi M et al (2005) The minimally conscious state and recovery potential: a follow-up study 2 to 5 years after traumatic brain injury. Arch Phys Med Rehabil 86:746–754

    Article  PubMed  Google Scholar 

  • Levin B (2006) Introduction to neuroimaging in traumatic brain injury. J Neurotrauma 23(10):1394–1396

    Article  Google Scholar 

  • Maas A, Hukkelhoven C, Marshall L et al (2005) Prediction of outcome in traumatic brain injury with computed tomographic characteristics a comparison between the computed tomographic classification and combinations of computed tomographic predictors. Neurosurgery 57:1173–1182

    Article  PubMed  Google Scholar 

  • Mannion R, Cross J, Bradley P et al (2007) Mechanism-based MRI classification of traumatic brainstem injury and its relationship to outcome. J Neurotrauma 24:128–135

    Article  PubMed  Google Scholar 

  • Marshall L, Marshall S, Klauber M, Clark M (1991) A new classification of head injury based on computerized tomography. J Neurosurg 75:14–20

    Google Scholar 

  • Maxwell W (2006) Thalamic nuclei after human blunt head injury. J Neuropathol Exp Neurol 65:478–488

    Article  PubMed  Google Scholar 

  • McMillan T, Herbert C (2004) Further recovery in a potential treatment withdrawal case 10 years after brain injury. Brain Inj 18:935–940

    Article  CAS  PubMed  Google Scholar 

  • Munkle MC et al (2000) The distribution of calbindin, calretinin and parvalbumin immunoreactivity in the human thalamus. J Chem Neuroanat 19:155–173

    Article  CAS  PubMed  Google Scholar 

  • Oknina L, Sharova E, Zaitsev O, Zakharova N, Masherov E, Schekutiev G, Kornienko V, Potapov A (2011) Long-latency components (N100, N200 and P300) of acoustic evoked potentials in prediction of mental recovery in severe traumatic brain injury. Zh Vopr Neurokhir im NNBurdenko 75(3):19–30

    CAS  Google Scholar 

  • Owen AM et al (2006) Detecting awareness in the vegetative state. Science 313:1402

    Article  CAS  PubMed  Google Scholar 

  • Posner J, Saper C, Schiff N, Plum F (2007) Plum and posner’s diagnosis of stupor and coma. In: Plum F, Posner J (eds) 4th edn. Oxford University Press, New York

    Google Scholar 

  • Potapov A, Likhterman L (2011) Management of severe traumatic brain injuries. In: Kalangu K, Kato Y, Dechambinoit G (eds) Essential practice of neurosurgery. WFNS/Asses Publishing Co Ltd, Japan

    Google Scholar 

  • Potapov A, Kravchuk A, Zakharova N (2009) Head trauma. In: Kornienko V, Pronin I (eds) Diagnostic neuroradiology. Springer, Heidelberg, pp 807–919

    Google Scholar 

  • Saatman K, Duhaime A, Bullock R et al (2008) Classification of traumatic brain injury for targeted therapies. J Neurotrauma 25:719–728

    Article  PubMed Central  PubMed  Google Scholar 

  • Schiff N (2008) Central thalamic contributions to arousal regulation and neurological disorders of consciousness. Ann N Y Acad Sci 1129:105–118

    Article  PubMed  Google Scholar 

  • Schiff N (2009) Recovery of consciousness after brain injury: a mesocircuit hypothesis. Trends Neurosci 33(1):1–9

    Article  PubMed Central  PubMed  Google Scholar 

  • Schiff N, Plum F (2000) The role of arousal and ‘gating’ systems in the neurology of impaired consciousness. J Clin Neurophysiol 17:438–452

    Article  CAS  PubMed  Google Scholar 

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Zakharova, N., Kornienko, V., Potapov, A., Pronin, I. (2014). Neuroimaging Classification of Traumatic Brain Injury. In: Neuroimaging of Traumatic Brain Injury. Springer, Cham. https://doi.org/10.1007/978-3-319-04355-5_3

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  • DOI: https://doi.org/10.1007/978-3-319-04355-5_3

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-04354-8

  • Online ISBN: 978-3-319-04355-5

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