Abstract
A DNA Microarray or a Gene Chip comprises of a collection of microscopic spots where each spot is a DNA sequence probe representing a single gene. The DNA sequences representing at a specific location are arrayed on a solid surface and attached to a chemically suitable matrix through covalent bonds. DNA microarrays are often used for expression profiling and rely on the strength of DNA-DNA hybridization and DNA-RNA hybridization to detect and measure gene expression levels.
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Singh, G.B. (2015). Microarrays. In: Fundamentals of Bioinformatics and Computational Biology. Modeling and Optimization in Science and Technologies, vol 6. Springer, Cham. https://doi.org/10.1007/978-3-319-11403-3_17
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DOI: https://doi.org/10.1007/978-3-319-11403-3_17
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-11402-6
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