Abstract
Pregnancy expresses a balance between tolerance and inflammation. The excessive and recurrent intake of similar food clusters and the excessive production of corresponding IgG antibodies could start a cause-effect reaction and an increase of inflammatory mediators. The evaluation of BAFF and PAF could allow to measure levels of inflammation related to the personal profile of food consumption and modulate specific dietary changes. The best nutritional profile for pregnancy should probably be the most varied as possible, within the criteria of major food pyramids adopted for millennia by different macro-ethnicities.
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References
Singh M, Chaudhry P, Asselin E. Bridging endometrial receptivity and implantation: network of hormones, cytokines, and growth factors. J Endocrinol. 2011;210:5–14. doi:10.1530/JOE-10-0461.
Hemberger M. Immune balance at the foeto-maternal interface as the fulcrum of reproductive success. J Reprod Immunol. 2013;97:36–42. doi:10.1016/j.jri.2012.10.006.
McMaster MT, Newton RC, Dey SK, Andrews GK. Activation and distribution of inflammatory cells in the mouse uterus during the preimplantation period. J Immunol. 1992;148:1699–705.
Robb L, Li R, Hartley L, et al. Infertility in female mice lacking the receptor for interleukin 11 is due to a defective uterine response to implantation. Nat Med. 1998;4:303–8.
Stewart CL, Kaspar P, Brunet LJ, et al. Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor. Nature. 1992;359:76–9. doi:10.1038/359076a0.
Erlebacher A, Zhang D, Parlow AF, Glimcher LH. Ovarian insufficiency and early pregnancy loss induced by activation of the innate immune system. J Clin Invest. 2004;114:39–48. doi:10.1172/JCI20645.
Cui L-L, Yang G, Pan J, Zhang C. Tumor necrosis factor α knockout increases fertility of mice. Theriogenology. 2011;75:867–76. doi:10.1016/j.theriogenology.2010.10.029.
Norwitz ER, Schust DJ, Fisher SJ. Implantation and the survival of early pregnancy. N Engl J Med. 2001;345:1400–8. doi:10.1056/NEJMra000763.
Solano ME, Jago C, Pincus MK, Arck PC. Highway to health; or how prenatal factors determine disease risks in the later life of the offspring. J Reprod Immunol. 2011;90:3–8. doi:10.1016/j.jri.2011.01.023.
Arck PC, Hecher K. Fetomaternal immune cross-talk and its consequences for maternal and offspring's health. Nat Med. 2013;19:548–56. doi:10.1038/nm.3160.
Hartwig IRV, Pincus MK, Diemert A, et al. Sex-specific effect of first-trimester maternal progesterone on birthweight. Hum Reprod. 2013;28:77–86. doi:10.1093/humrep/des367.
Arck PC, Rücke M, Rose M, et al. Early risk factors for miscarriage: a prospective cohort study in pregnant women. Reprod Biomed Online. 2008;17:101–13.
Bach J-F. The effect of infections on susceptibility to autoimmune and allergic diseases. N Engl J Med. 2002;347:911–20. doi:10.1056/NEJMra020100.
Brannon PM. Vitamin D and adverse pregnancy outcomes: beyond bone health and growth. Proc Nutr Soc. 2012;71:205–12. doi:10.1017/S0029665111003399.
Sherman PW, Flaxman SM. Nausea and vomiting of pregnancy in an evolutionary perspective. Am J Obstet Gynecol. 2002;186:S190–7. doi:10.1067/mob.2002.122593.
Ligaarden SC, Lydersen S, Farup PG. IgG and IgG4 antibodies in subjects with irritable bowel syndrome: a case control study in the general population. BMC Gastroenterol. 2012;12:166. doi:10.1186/1471-230X-12-166.
Speciani AF, Piuri G, Ferrazzi E. IgG levels to food correlate with nutritional exposure to food antigens but a methodological weakness of this research prevents the recognition of yeast- related foods as a possible cause of Irritable Bowel Syndrome (IBS). Comment to IgG and IgG4 antibodies in subjects with irritable bowel syndrome: a case control study in the general population. Published on 2014/02/20. BMC Gastroenterol. 2012;12:166. doi:10.1186/1471-230X-12-166. http://www.biomedcentral.com/1471-230X/12/166/comments
Wisniewski J, Agrawal R, Woodfolk JA. Mechanisms of tolerance induction in allergic disease: integrating current and emerging concepts. Clin Exp Allergy. 2013;43:164–76. doi:10.1111/cea.12016.
van der Neut Kolfschoten M, Schuurman J, Losen M, et al. Anti-inflammatory activity of human IgG4 antibodies by dynamic Fab arm exchange. Science. 2007;317:1554–7. doi:10.1126/science.1144603.
Finkelman FD. Anaphylaxis: lessons from mouse models. J Allergy Clin Immunol. 2007;120:506–15– quiz 516–7. doi: 10.1016/j.jaci.2007.07.033.
Khodoun MV, Strait R, Armstrong L, et al. Identification of markers that distinguish IgE- from IgG-mediated anaphylaxis. Proc Natl Acad Sci U S A. 2011;108:12413–8. doi:10.1073/pnas.1105695108.
Piuri G, Soriano J, Speciani MC, Speciani AF. B cell activating factor (BAFF) and platelet activating factor (PAF) could both be markers of non-IgE-mediated reactions. Clin Transl Allergy. 2013;3:O5. doi:10.1016/j.jaci.2007.07.033.
Piuri G, Bulfoni C, Mastricci AL, Speciani AF, Ferrazzi E. Two innovative inflammation biomarkers for the measurement of inflammation in pregnancy. Paper presented at the 24th European Congress of Perinatal Medicie (ECPM), Florence, 4–7 June 2014.
Speciani AF, Soriano J, Speciani MC, Piuri G. Five great food clusters of specific IgG for 44 common food antigens. A new approach to the epidemiology of food allergy. Clin Transl Allergy. 2013;3:P67. doi:10.1186/2045-7022-3-S3-P67.
Speciani AF, Piuri G, Soriano J, Ferrazzi E. A larger study of food-related IgG confirms the possible new epidemiological approach to non-IgE-mediated reactions and suggests five great food clusters. Paper presented at 3rd Food Allergy and Anaphylaxis Meeting (FAAM), Dublin, 9–11 Oct 2014.
Speciani AF. Measuring biomarkers for an innovative food personal profile. Lesson at 3rd international congress science in nutrition “anti-inflammation, quality of life and sport in nutrition.” Milan 14–15 March 2014.
Roduit C, Frei R, Depner M, et al. Increased food diversity in the first year of life is inversely associated with allergic diseases. J Allergy Clin Immunol. 2014;133:1056–64. doi:10.1016/j.jaci.2013.12.1044.
Nwaru BI, Takkinen H-M, Kaila M, et al. Food diversity in infancy and the risk of childhood asthma and allergies. J Allergy Clin Immunol. 2014;133:1084–91. doi:10.1016/j.jaci.2013.12.1069.
Greer FR, Sicherer SH, Burks AW, Committee on Nutrition and Section on Allergy and Immunology. Effects of Early Nutritional Interventions on the Development of Atopic Disease in Infants and Children: The Role of Maternal Dietary Restriction, Breastfeeding, Timing of Introduction of Complementary Foods, and Hydrolyzed Formulas. Pediatrics. 2008;121:183–91. doi:10.1542/peds. 2007-3022.
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Piuri, G. (2015). Individual Food Clusters Excess and Low-Grade Inflammation in Pregnancy. In: Ferrazzi, E., Sears, B. (eds) Metabolic Syndrome and Complications of Pregnancy. Springer, Cham. https://doi.org/10.1007/978-3-319-16853-1_2
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DOI: https://doi.org/10.1007/978-3-319-16853-1_2
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