Skip to main content

Mitral Stenosis After Edge-to-Edge Repair: Is It an Issue?

  • Chapter
Edge-to-Edge Mitral Repair

Abstract

The edge-to-edge (EE) repair, also known as “Alfieri’s stitch” is a reproducible and effective technique to restore mitral valve (MV) competence. When this technique is applied in the central part of the anterior and posterior MV leaflets, two orifices are created and the effective MV area is significantly reduced.3D-computational models and in vitro studies have demonstrated that the hemodynamic performance of a double orifice valve is similar to that of a single orifice one with the same total effective orifice area.Clinical experience and sperimental dataassess that functional MS doesn’t exist. It can be possible to have an anatomical post surgical MS and according to computational models it is important to mantain a residual area larger than 2.5 cm2 in normal size patient.Major risk factors of post EE repair MS are: small native area, large intercommissural width of lesion and extention of surgical suture, restrictiveannuloplasty.All the standard echocardiographic parameters and derived calculation for the assessment of significantMS, described in literature, have some limitations expecially in the intraoperative setting, in wich it is very important to assess the 2D planimetric or 3Dtotal area of the two orefice.The use 3D echocardiography assessment of the double orefice area is becoming the gold standard for the evaluation of possible post surgical repair MS.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 54.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Fedak PWM, McCarthy PM, Bonow RO. Evolving concepts and technologies in mitral valve repair. Circulation. 2008;117:963–74.

    Article  PubMed  Google Scholar 

  2. Maisano F, Schreuder JJ, Oppizzi M, Fiorani B, Fino C, Alfieri O. The double-orifice technique as a standardized approach to treat mitral regurgitation due to severe myxomatous disease: surgical technique. Eur J Cardiothorac Surg. 2000;17:201–5.

    Article  CAS  PubMed  Google Scholar 

  3. De Bonis M, Alfieri O. The edge-to-edge technique for mitral valve repair. HSR Proc Intensive Care Cardiovasc Anesth. 2010;2(1):7–17.

    PubMed Central  PubMed  Google Scholar 

  4. Takeshita K, Inden Y, Murohara T. Coincidental finding of isolated congenital double-orifice mitral valve in two adult patients. Eur J Echocardiogr. 2011;12(3), E26.

    Article  PubMed  Google Scholar 

  5. Patted SV, Halkati PC, Ambar SS, Sattur AG. Successful treatment of double-orifice mitral stenosis with percutaneous balloon mitral commissurotomy. Case Rep Cardiol. 2012;2012:315175.

    PubMed Central  PubMed  Google Scholar 

  6. Trowitzsch E, Bano-Rodrigo A, Burger BM, Colan SD, Sanders SP. Two-dimensional echocardiographic findings in double orifice mitral valve. J Am Coll Cardiol. 1985;6(2):383–7.

    Article  CAS  PubMed  Google Scholar 

  7. Allen HD, Gutgesell HP, Clark EB, Driscoll DJ. Moss and Adams’ heart disease in infants, children, and adolescents: including the fetus and young adult. Lippincott Williams & Wilkins 7th ed. 2008.

    Google Scholar 

  8. Westendorp IC, de Bruin-Bon HA, Hrudova J. Double orifice mitral valve; a coincidental finding. Eur J Echocardiogr. 2006;7(6):463–4.

    Article  PubMed  Google Scholar 

  9. Zalzstein E, Hamilton R, Zucker N, et al. Presentation, natural history, and outcome in children and adolescents with double orifice mitral valve. Am J Cardiol. 2004;93:1067–9.

    Article  PubMed  Google Scholar 

  10. Votta E, Maisano F, Soncini M, Redaelli A, Montevecchi FM, Alfieri O. 3-D computational analysis of the stress distribution on the leaflets after edge-to-edge repair of mitral regurgitation. J Heart Valve Dis. 2002;11:810–22.

    PubMed  Google Scholar 

  11. Maisano F, Redaelli A, Pennati G, et al. The hemodynamic effects of double-orifice valve repair for mitral regurgitation: a 3D computational model. Eur J Cardiothorac Surg. 1999;15:419–25.

    Article  CAS  PubMed  Google Scholar 

  12. De Bonis M, Lapenna E, Lorusso R, Buzzatti N, Gelsomino S, Taramasso M, Vizzardi E, Alfieri O. Very long-term results (up to 17 years) with the double-orifice mitral valve repair combined with ring annuloplasty for degenerative mitral regurgitation. J Thorac Cardiovasc Surg. 2012;144:1019–24.

    Article  PubMed  Google Scholar 

  13. De Bonis M, Lapenna E, Maisano F, Barili F, La Canna G, Buzzatti N, Pappalardo F, Calabrese M, Nisi T, Alfieri O. Long-term results (≤18 years) of the edge-to-edge mitral valve repair without annuloplasty in degenerative mitral regurgitation: implications for the percutaneous approach. Circulation. 2014;130(11 Suppl 1):S19–24.

    Article  PubMed  Google Scholar 

  14. Frapier JM, Sportouch C, Rauzy V, et al. Mitral valve repair by Alfieri’s technique does not limit exercise tolerance more than Carpentier’s correction. Eur J Cardiothorac Surg. 2006;29:1020–5.

    Article  PubMed  Google Scholar 

  15. Bonser DRS, Pagano D, Laverich A. Mitral valve surgery book. Chapter 8. Book Springer 2011. p. 77–84.

    Google Scholar 

  16. Maisano F, Torracca L, Oppizzi M, Stefano PL, D’Addario G, La Canna G, et al. The edge-to-edge technique: a simplified method to correct mitral insufficiency. Eur J Cardiothorac Surg. 1998;13:240–5.

    Article  CAS  PubMed  Google Scholar 

  17. Maisano F, Caldarola A, Blasio A, De Bonis M, La Canna G, Alfieri O. Midterm results of edge-to-edge mitral valve repair without annuloplasty. J Thorac Cardiovasc Surg. 2003;126(6):1987–97.

    Article  PubMed  Google Scholar 

  18. Agricola E, Maisano F, Oppizzi M, La Canna G, Alfieri O. Mitral valve reserve in double-orifice technique: an exercise echocardiographic study. J Heart Valve Dis. 2002;11:637–43.

    PubMed  Google Scholar 

  19. Fedak PWM, McCarthy PM, Patrick M, Bonow RO. Evolving concepts and technologies in Mitral Valve Repair Circulation. 2008;117(7):963–74.

    Google Scholar 

  20. Feldman SK, Rinaldi M, Fail P, Hermiller J, Smalling R, Whitlow PL, et al. Percutaneous mitral repair with the MitraClip system: safety and midterm durability in the initial EVEREST (Endovascular Valve Edge-to-Edge Repair Study) cohort. J Am Coll Cardiol. 2009;54(8):686–94. Ted.

    Article  PubMed  Google Scholar 

  21. Herrmann HC, Rohatgi S, Wasserman HS, Block P, Gray W, Hamilton A, Zunamon A, Homma S, Di Tullio MR, Kraybill K, Merlino J, Martin R, Rodriguez L, Stewart WJ, Whitlow P, Wiegers SE, Silvestry FE, Foster E, Feldman T. Mitral valve hemodynamic effects of percutaneous edge-to-edge repair with the MitraClip device for mitral regurgitation. Catheter Cardiovasc Interv. 2006;68:821–8.

    Article  PubMed  Google Scholar 

  22. Chandrashekhar Y, Westaby S, Narula J. Mitral stenosis. Lancet. 2009;74(9697):1271–83.

    Article  Google Scholar 

  23. Nishimura RA, Otto CM, Bonow RO, Carabello BA, Erwin 3rd JP, Guyton RA, O’Gara PT, Ruiz CE, Skubas NJ, Sorajja P, Sundt 3rd TM, Thomas JD, American College of Cardiology/American Heart Association Task Force on Practice Guidelines. AHA/ACC guideline for the management of patients with valvular heart disease: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2014;63(22):2438–88.

    Article  PubMed  Google Scholar 

  24. Baumgartner H, Hung J, Bermejo J, Chambers JB, Evangelista A, Griffin BP, Iung B, Otto CM, Pellikka PA, Quiñones M, American Society of Echocardiography, European Association of Echocardiography. Echocardiographic assessment of valve stenosis: EAE/ASE recommendations for clinical practise. J Am Soc Echocardiogr. 2009;22(1):1–23.

    Article  PubMed  Google Scholar 

  25. Picano E, Pibarot P, Lancellotti P, Monin JL, Bonow RO. The emerging role of exercise testing and stress echocardiography in valvular heart disease. J Am Coll Cardiol. 2009;54(24):2251–60.

    Article  PubMed  Google Scholar 

  26. Fino C, Iacovoni A, Ferrero P, Senni M, Merlo M, Cugola D, Ferrazzi P, Caputo M, Miceli A, Magne J. Restrictive mitral valve annuloplasty versus mitral valve replacement for functional ischemic mitral regurgitation: an exercise echocardiographic study. J Thorac Cardiovasc Surg. 2014;148(2):447–53.e2. doi:10.1016/j.jtcvs.2013.05.053. Epub 2013 Nov 4.

    Article  PubMed  Google Scholar 

  27. Chan KL, Chen SY, Chan V, Hay K, Mesana T, Lam BK. Functional significance of elevated mitral gradients after repair for degenerative mitral regurgitation. Circ Cardiovasc Imaging. 2013;6(6):1041–7.

    Article  PubMed  Google Scholar 

  28. Riegel AK, Bush R, Segal S, Fox JA, Eltzshing HK, Shernan SK. Evaluation of transmitral pressure gradients in the intraoperative echocardiographic diagnosis of mitral stenosis after mitral valve repair. PLoS One. 2011;6(11), e26559.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  29. Armstrong WF, Ryan T. Feigenbaum’s echocardiography. 7th ed. Philadelphia: Lippincott Williams and Wilkins; 2009.

    Google Scholar 

  30. Savage RM, Aronson S, Thomas JD, Shanewise JS, Shernan SK. Comprehensive textbook of intraoperative transesophageal echocardiography. Philadelphia: Lippincott Williams and Wilkins; 2004.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Giovanna Di Giannuario .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Di Giannuario, G., La Canna, G. (2015). Mitral Stenosis After Edge-to-Edge Repair: Is It an Issue?. In: Alfieri, O., De Bonis, M., La Canna, G. (eds) Edge-to-Edge Mitral Repair. Springer, Cham. https://doi.org/10.1007/978-3-319-19893-4_9

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-19893-4_9

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-19892-7

  • Online ISBN: 978-3-319-19893-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics