Abstract
Coloboma is a developmental abnormality with defects of one or several ocular structures. Defects of the eyelids, cornea, iris, ciliary body, zonules, lens, retina, choroid, and/or optic nerve may be present and are caused by incomplete closure of the embryonic fissure.
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References and Suggested Reading
Kenneth W. Wright. Diseases of the cornea. anterior segment, and iris. In: Pediatric ophthalmology and strabismus, vol. 6. San Francisco: American Academy of Ophthalmology. p. 252, 356.
Warburg M. Classification of microphthalmos and coloboma. J Med Genet. 1993;30(8):664–9.
Stoll C, Alembik Y, Dott B, Roth MP. Epidemiology of congenital eye malformations in 131,760 consecutive births. Ophthalmic Paediatr Genet. 1992;13(3):179–86.
Schubert HD. Structural organization of choroidal colobomas of young and adult patients and mechanism of retinal detachment. Trans Am Ophthalmol Soc. 2005;103:457–72.
Facts About Uveal Coloboma (2012) Retrieved 12 July 2015, from https://nei.nih.gov/health/coloboma/coloboma.
Coloboma (2011) Retrieved 12 July 2015, from http://ghr.nlm.nih.gov/condition/coloboma.
Gregory-Evans CY, Williams MJ, Halford S, Gregory-Evans K. Ocular coloboma: a reassessment in the age of molecular neuroscience. J Med Genet. 2004;41(12):881–91. Review.
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Patel, H.R., Bhaleeya, S. (2016). Coloboma. In: Medina, C., Townsend, J., Singh, A. (eds) Manual of Retinal Diseases. Springer, Cham. https://doi.org/10.1007/978-3-319-20460-4_16
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DOI: https://doi.org/10.1007/978-3-319-20460-4_16
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