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Advanced Therapy for Venous Thromboembolism: Understanding the Role of Systemic Fibrinolysis, Catheter-Based Therapy, and Surgery

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Handbook for Venous Thromboembolism

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Abstract

Selection of patients with venous thromboembolism (VTE) for advanced therapies requires recognition of high-risk deep vein thrombosis (DVT) and pulmonary embolism (PE) syndromes. Advanced therapies for acute PE include systemic fibrinolysis, catheter-based “pharmacomechanical” intervention, and surgical pulmonary embolectomy. Choosing a particular advanced therapy depends on the individual patient’s risk for adverse outcomes due to VTE and for major bleeding, specifically intracranial hemorrhage. Multidisciplinary PE Response Teams may facilitate access to advanced therapies and appropriate patient selection.

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Authors and Affiliations

  1. Cardiovascular Division, Harvard Medical School Brigham and Women’s Hospital, Boston, Massachusetts, USA

    Gregory Piazza

  2. Department of Pharmacy Services, Brigham and Women’s Hospital, Boston, Massachusetts, USA

    Benjamin Hohlfelder

  3. Thrombosis Research Group, Harvard Medical School Brigham and Women’s Hospital, Boston, Massachusetts, USA

    Samuel Z. Goldhaber

Authors
  1. Gregory Piazza
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  2. Benjamin Hohlfelder
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  3. Samuel Z. Goldhaber
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Piazza, G., Hohlfelder, B., Goldhaber, S.Z. (2015). Advanced Therapy for Venous Thromboembolism: Understanding the Role of Systemic Fibrinolysis, Catheter-Based Therapy, and Surgery. In: Handbook for Venous Thromboembolism. Springer, Cham. https://doi.org/10.1007/978-3-319-20843-5_7

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  • DOI: https://doi.org/10.1007/978-3-319-20843-5_7

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-20842-8

  • Online ISBN: 978-3-319-20843-5

  • eBook Packages: MedicineMedicine (R0)

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