Abstract
Cap polyposis is a rare sporadic disorder of the colon recognized by the presence of inflammatory polyps covered by a fibrinopurulent exudative cap. It predominantly affects women in the fifth decade of life but can be seen in both sexes with a wide range age of onset. The exact pathogenesis of this condition is not known but its association with E. coli and H. pylori infection as well as motility disorders of the colon has been reported. Red- and white-capped polyps with a wide range of numbers ranging from one to hundreds of lesions can be detected in the entire colon during the endoscopic exam. Histologically elongated crypts with superficial attenuation of the epithelium are generally reported. Affected individuals could be asymptomatic, although rectal bleeding, diarrhea, and constipation are commonly seen with this condition. Due to the rarity of this disorder, a well-established therapeutic approach is lacking, however, response to antibiotic, anti-inflammatory, and immunosuppressive therapies has been reported in the literature.
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De Petris, G., Rashtak, S. (2016). Inflammatory “Cap” Polyposis. In: Boardman, L. (eds) Intestinal Polyposis Syndromes. Springer, Cham. https://doi.org/10.1007/978-3-319-28103-2_3
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DOI: https://doi.org/10.1007/978-3-319-28103-2_3
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